PhosphoNET

           
Protein Info 
   
Short Name:  TMEM52
Full Name:  Transmembrane protein 52
Alias: 
Type: 
Mass (Da):  22122
Number AA:  209
UniProt ID:  Q8NDY8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S37ALGFADGSCDPSDQC
Site 2S41ADGSCDPSDQCPPQA
Site 3S52PPQARWSSLWHVGLI
Site 4S109VIPMDSDSPVHSTVT
Site 5S113DSDSPVHSTVTSYSS
Site 6T114SDSPVHSTVTSYSSV
Site 7T116SPVHSTVTSYSSVQY
Site 8S117PVHSTVTSYSSVQYP
Site 9S119HSTVTSYSSVQYPLG
Site 10S120STVTSYSSVQYPLGM
Site 11Y123TSYSSVQYPLGMRLP
Site 12S140FGELDLDSMAPPAYS
Site 13Y146DSMAPPAYSLYTPEP
Site 14S147SMAPPAYSLYTPEPP
Site 15Y149APPAYSLYTPEPPPS
Site 16T150PPAYSLYTPEPPPSY
Site 17S156YTPEPPPSYDEAVKM
Site 18Y157TPEPPPSYDEAVKMA
Site 19S174REEGPALSQKPSPLL
Site 20S178PALSQKPSPLLGASG
Site 21T188LGASGLETTPVPQES
Site 22T189GASGLETTPVPQESG
Site 23S195TTPVPQESGPNTQLP
Site 24T199PQESGPNTQLPPCSP
Site 25S205NTQLPPCSPGAP___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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