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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF540
Full Name:
Zinc finger protein 540
Alias:
Type:
Mass (Da):
77094
Number AA:
660
UniProt ID:
Q8NDQ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
E
W
E
C
L
D
T
T
Q
R
K
L
Y
R
D
Site 2
Y31
D
T
T
Q
R
K
L
Y
R
D
V
M
L
E
N
Site 3
Y39
R
D
V
M
L
E
N
Y
N
N
L
V
S
L
G
Site 4
S44
E
N
Y
N
N
L
V
S
L
G
Y
S
G
S
K
Site 5
T56
G
S
K
P
D
V
I
T
L
L
E
Q
G
K
E
Site 6
T85
G
L
L
S
R
H
K
T
K
K
L
S
S
E
K
Site 7
S90
H
K
T
K
K
L
S
S
E
K
D
I
H
E
I
Site 8
S98
E
K
D
I
H
E
I
S
L
S
K
E
S
I
I
Site 9
S100
D
I
H
E
I
S
L
S
K
E
S
I
I
E
K
Site 10
S108
K
E
S
I
I
E
K
S
K
T
L
R
L
K
G
Site 11
T110
S
I
I
E
K
S
K
T
L
R
L
K
G
S
I
Site 12
S116
K
T
L
R
L
K
G
S
I
F
R
N
E
W
Q
Site 13
S126
R
N
E
W
Q
N
K
S
E
F
E
G
Q
Q
G
Site 14
S140
G
L
K
E
R
S
I
S
Q
K
K
I
V
S
K
Site 15
S146
I
S
Q
K
K
I
V
S
K
K
M
S
T
D
R
Site 16
S150
K
I
V
S
K
K
M
S
T
D
R
K
R
P
S
Site 17
T151
I
V
S
K
K
M
S
T
D
R
K
R
P
S
F
Site 18
S157
S
T
D
R
K
R
P
S
F
T
L
N
Q
R
I
Site 19
T159
D
R
K
R
P
S
F
T
L
N
Q
R
I
H
N
Site 20
S167
L
N
Q
R
I
H
N
S
E
K
S
C
D
S
H
Site 21
S170
R
I
H
N
S
E
K
S
C
D
S
H
L
V
Q
Site 22
S173
N
S
E
K
S
C
D
S
H
L
V
Q
H
G
K
Site 23
S225
E
K
C
G
K
V
F
S
H
S
Y
Q
L
T
L
Site 24
T231
F
S
H
S
Y
Q
L
T
L
H
Q
R
F
H
T
Site 25
T238
T
L
H
Q
R
F
H
T
G
E
K
P
Y
E
C
Site 26
Y243
F
H
T
G
E
K
P
Y
E
C
Q
E
C
G
K
Site 27
T251
E
C
Q
E
C
G
K
T
F
T
L
Y
P
Q
L
Site 28
T253
Q
E
C
G
K
T
F
T
L
Y
P
Q
L
N
R
Site 29
Y255
C
G
K
T
F
T
L
Y
P
Q
L
N
R
H
Q
Site 30
S282
K
C
D
K
G
F
F
S
R
L
E
L
T
Q
H
Site 31
T287
F
F
S
R
L
E
L
T
Q
H
K
R
I
H
T
Site 32
T294
T
Q
H
K
R
I
H
T
G
K
K
S
Y
E
C
Site 33
Y299
I
H
T
G
K
K
S
Y
E
C
K
E
C
G
K
Site 34
Y313
K
V
F
Q
L
I
F
Y
F
K
E
H
E
R
I
Site 35
T322
K
E
H
E
R
I
H
T
G
K
K
P
Y
E
C
Site 36
Y327
I
H
T
G
K
K
P
Y
E
C
K
E
C
G
K
Site 37
S337
K
E
C
G
K
A
F
S
V
C
G
Q
L
T
R
Site 38
Y355
I
H
T
G
V
K
P
Y
E
C
K
E
C
G
K
Site 39
T363
E
C
K
E
C
G
K
T
F
R
L
S
F
Y
L
Site 40
S367
C
G
K
T
F
R
L
S
F
Y
L
T
E
H
R
Site 41
Y369
K
T
F
R
L
S
F
Y
L
T
E
H
R
R
T
Site 42
T371
F
R
L
S
F
Y
L
T
E
H
R
R
T
H
A
Site 43
T376
Y
L
T
E
H
R
R
T
H
A
G
K
K
P
Y
Site 44
Y383
T
H
A
G
K
K
P
Y
E
C
K
E
C
G
K
Site 45
S391
E
C
K
E
C
G
K
S
F
N
V
R
G
Q
L
Site 46
T403
G
Q
L
N
R
H
K
T
I
H
T
G
I
K
P
Site 47
S421
K
V
C
E
K
A
F
S
Y
S
G
D
L
R
V
Site 48
S430
S
G
D
L
R
V
H
S
R
I
H
T
G
E
K
Site 49
T434
R
V
H
S
R
I
H
T
G
E
K
P
Y
E
C
Site 50
Y439
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 51
S452
G
K
A
F
M
L
R
S
V
L
T
E
H
Q
R
Site 52
T455
F
M
L
R
S
V
L
T
E
H
Q
R
L
H
T
Site 53
T462
T
E
H
Q
R
L
H
T
G
V
K
P
Y
E
C
Site 54
Y467
L
H
T
G
V
K
P
Y
E
C
K
E
C
G
K
Site 55
T475
E
C
K
E
C
G
K
T
F
R
V
R
S
Q
I
Site 56
S480
G
K
T
F
R
V
R
S
Q
I
S
L
H
K
K
Site 57
S483
F
R
V
R
S
Q
I
S
L
H
K
K
I
H
T
Site 58
Y495
I
H
T
D
V
K
P
Y
K
C
V
R
C
G
K
Site 59
T518
T
E
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 60
Y523
I
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 61
Y551
I
H
S
G
L
K
P
Y
D
C
K
E
C
G
K
Site 62
S559
D
C
K
E
C
G
K
S
F
S
R
R
G
Q
F
Site 63
S561
K
E
C
G
K
S
F
S
R
R
G
Q
F
T
E
Site 64
T567
F
S
R
R
G
Q
F
T
E
H
Q
K
I
H
T
Site 65
S589
K
E
C
G
K
A
F
S
R
S
V
D
L
R
I
Site 66
S591
C
G
K
A
F
S
R
S
V
D
L
R
I
H
Q
Site 67
T602
R
I
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 68
Y607
I
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 69
S620
G
K
A
F
R
L
N
S
H
L
T
E
H
Q
R
Site 70
T623
F
R
L
N
S
H
L
T
E
H
Q
R
I
H
T
Site 71
T630
T
E
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 72
Y647
C
R
K
A
F
R
Q
Y
S
H
L
Y
Q
H
Q
Site 73
Y651
F
R
Q
Y
S
H
L
Y
Q
H
Q
K
T
H
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation