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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NPEPL1
Full Name:
Probable aminopeptidase NPEPL1
Alias:
Aminopeptidase-like 1
Type:
Mass (Da):
55843
Number AA:
523
UniProt ID:
Q8NDH3
International Prot ID:
IPI00100292
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004177
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
G
L
Q
F
Q
A
S
A
G
D
S
D
P
Q
Site 2
S15
F
Q
A
S
A
G
D
S
D
P
Q
S
R
P
L
Site 3
S19
A
G
D
S
D
P
Q
S
R
P
L
L
L
L
G
Site 4
T48
G
K
L
Q
P
R
V
T
E
E
L
W
Q
A
A
Site 5
S57
E
L
W
Q
A
A
L
S
T
L
N
P
N
P
T
Site 6
T58
L
W
Q
A
A
L
S
T
L
N
P
N
P
T
D
Site 7
T64
S
T
L
N
P
N
P
T
D
S
C
P
L
Y
L
Site 8
S66
L
N
P
N
P
T
D
S
C
P
L
Y
L
N
Y
Site 9
S84
A
A
L
P
C
R
V
S
R
H
N
S
P
S
A
Site 10
S88
C
R
V
S
R
H
N
S
P
S
A
A
H
F
I
Site 11
S90
V
S
R
H
N
S
P
S
A
A
H
F
I
T
R
Site 12
T96
P
S
A
A
H
F
I
T
R
L
V
R
T
C
L
Site 13
T135
A
R
A
F
P
L
F
T
H
R
S
G
A
S
R
Site 14
S138
F
P
L
F
T
H
R
S
G
A
S
R
R
L
E
Site 15
T148
S
R
R
L
E
K
K
T
V
T
V
E
F
F
L
Site 16
T187
L
A
A
R
I
V
D
T
P
C
N
E
M
N
T
Site 17
T222
I
R
D
E
E
L
K
T
R
G
F
G
G
I
Y
Site 18
Y229
T
R
G
F
G
G
I
Y
G
V
G
K
A
A
L
Site 19
T266
G
K
G
I
V
Y
D
T
G
G
L
S
I
K
G
Site 20
S270
V
Y
D
T
G
G
L
S
I
K
G
K
T
T
M
Site 21
Y331
P
D
D
I
H
L
L
Y
S
G
K
T
V
E
I
Site 22
T335
H
L
L
Y
S
G
K
T
V
E
I
N
N
T
D
Site 23
T341
K
T
V
E
I
N
N
T
D
A
E
G
R
L
V
Site 24
Y382
Q
G
I
A
T
G
K
Y
H
A
A
V
L
T
N
Site 25
S424
L
H
F
S
E
F
T
S
A
V
A
D
M
K
N
Site 26
S432
A
V
A
D
M
K
N
S
V
A
D
R
D
N
S
Site 27
S439
S
V
A
D
R
D
N
S
P
S
S
C
A
G
L
Site 28
S441
A
D
R
D
N
S
P
S
S
C
A
G
L
F
I
Site 29
S442
D
R
D
N
S
P
S
S
C
A
G
L
F
I
A
Site 30
S517
E
G
D
L
G
R
D
S
K
R
R
R
L
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation