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Updated November 2019
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Protein Info
Short Name:
LOC643677
Full Name:
Uncharacterized protein C13orf40
Alias:
similar to temporarily assigned gene name family member (tag-58)
Type:
Mass (Da):
277951
Number AA:
2452
UniProt ID:
Q8NDH2
International Prot ID:
IPI00886969
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
Q
K
D
K
A
N
I
S
E
K
S
V
M
H
P
Site 2
S15
K
A
N
I
S
E
K
S
V
M
H
P
E
Y
I
Site 3
Y21
K
S
V
M
H
P
E
Y
I
A
V
K
A
E
K
Site 4
S32
K
A
E
K
S
P
L
S
H
I
L
K
T
K
E
Site 5
S45
K
E
L
Q
V
N
I
S
Q
Q
G
E
K
A
Q
Site 6
S79
S
A
F
L
E
L
D
S
I
K
E
E
E
G
E
Site 7
T90
E
E
G
E
P
R
I
T
R
S
F
M
P
H
L
Site 8
S92
G
E
P
R
I
T
R
S
F
M
P
H
L
E
I
Site 9
S102
P
H
L
E
I
Q
E
S
L
P
S
R
Q
T
A
Site 10
S105
E
I
Q
E
S
L
P
S
R
Q
T
A
P
T
K
Site 11
T108
E
S
L
P
S
R
Q
T
A
P
T
K
P
T
E
Site 12
T111
P
S
R
Q
T
A
P
T
K
P
T
E
S
L
V
Site 13
S116
A
P
T
K
P
T
E
S
L
V
K
K
E
K
Q
Site 14
T134
Q
K
E
D
R
V
Q
T
V
S
M
H
G
L
M
Site 15
S136
E
D
R
V
Q
T
V
S
M
H
G
L
M
H
P
Site 16
T162
P
P
Q
V
F
S
I
T
E
H
S
P
L
S
K
Site 17
S165
V
F
S
I
T
E
H
S
P
L
S
K
R
K
E
Site 18
S168
I
T
E
H
S
P
L
S
K
R
K
E
P
Q
W
Site 19
T188
A
G
Q
K
Q
D
R
T
G
R
P
H
V
I
L
Site 20
S204
K
T
H
P
F
M
P
S
L
S
H
H
R
F
S
Site 21
S206
H
P
F
M
P
S
L
S
H
H
R
F
S
P
S
Site 22
S211
S
L
S
H
H
R
F
S
P
S
Q
P
K
L
P
Site 23
S213
S
H
H
R
F
S
P
S
Q
P
K
L
P
I
S
Site 24
S220
S
Q
P
K
L
P
I
S
S
G
A
G
K
S
R
Site 25
S226
I
S
S
G
A
G
K
S
R
L
A
N
S
N
E
Site 26
S231
G
K
S
R
L
A
N
S
N
E
G
I
S
S
H
Site 27
S237
N
S
N
E
G
I
S
S
H
K
V
I
L
K
A
Site 28
S290
L
C
N
G
K
N
Y
S
L
H
I
E
E
Q
G
Site 29
S314
P
G
V
V
P
R
K
S
A
S
F
P
P
P
P
Site 30
S316
V
V
P
R
K
S
A
S
F
P
P
P
P
F
Y
Site 31
Y323
S
F
P
P
P
P
F
Y
L
N
C
D
T
R
R
Site 32
T328
P
F
Y
L
N
C
D
T
R
R
N
E
K
E
G
Site 33
T336
R
R
N
E
K
E
G
T
L
G
K
T
Q
F
S
Site 34
T340
K
E
G
T
L
G
K
T
Q
F
S
F
P
P
L
Site 35
S343
T
L
G
K
T
Q
F
S
F
P
P
L
K
I
Q
Site 36
S352
P
P
L
K
I
Q
D
S
S
D
S
G
K
K
A
Site 37
S353
P
L
K
I
Q
D
S
S
D
S
G
K
K
A
Y
Site 38
Y360
S
D
S
G
K
K
A
Y
T
E
S
L
H
G
Y
Site 39
T361
D
S
G
K
K
A
Y
T
E
S
L
H
G
Y
T
Site 40
S363
G
K
K
A
Y
T
E
S
L
H
G
Y
T
L
S
Site 41
Y367
Y
T
E
S
L
H
G
Y
T
L
S
N
S
K
G
Site 42
T368
T
E
S
L
H
G
Y
T
L
S
N
S
K
G
P
Site 43
S370
S
L
H
G
Y
T
L
S
N
S
K
G
P
V
Q
Site 44
S372
H
G
Y
T
L
S
N
S
K
G
P
V
Q
P
T
Site 45
S411
K
A
K
Q
L
L
L
S
D
I
L
N
T
K
K
Site 46
S423
T
K
K
L
Q
W
K
S
K
E
Q
K
R
K
I
Site 47
S443
K
Q
V
K
G
L
P
S
I
N
T
S
L
L
T
Site 48
T446
K
G
L
P
S
I
N
T
S
L
L
T
P
P
Y
Site 49
T450
S
I
N
T
S
L
L
T
P
P
Y
L
K
F
D
Site 50
Y453
T
S
L
L
T
P
P
Y
L
K
F
D
T
T
E
Site 51
T458
P
P
Y
L
K
F
D
T
T
E
G
Q
E
N
V
Site 52
T459
P
Y
L
K
F
D
T
T
E
G
Q
E
N
V
I
Site 53
S472
V
I
R
I
A
K
V
S
L
P
Q
S
R
S
K
Site 54
S476
A
K
V
S
L
P
Q
S
R
S
K
E
S
S
D
Site 55
S478
V
S
L
P
Q
S
R
S
K
E
S
S
D
A
G
Site 56
S482
Q
S
R
S
K
E
S
S
D
A
G
R
I
A
C
Site 57
S499
A
T
H
G
E
L
S
S
D
V
K
Q
L
K
A
Site 58
T523
R
E
K
V
A
D
M
T
S
V
L
D
P
N
K
Site 59
Y532
V
L
D
P
N
K
M
Y
L
K
A
K
K
S
P
Site 60
S538
M
Y
L
K
A
K
K
S
P
V
L
H
T
H
S
Site 61
T543
K
K
S
P
V
L
H
T
H
S
F
S
D
L
Q
Site 62
S545
S
P
V
L
H
T
H
S
F
S
D
L
Q
W
K
Site 63
S566
E
K
V
Q
K
V
K
S
G
P
G
V
M
L
S
Site 64
S573
S
G
P
G
V
M
L
S
K
S
P
S
R
S
S
Site 65
S575
P
G
V
M
L
S
K
S
P
S
R
S
S
P
L
Site 66
S577
V
M
L
S
K
S
P
S
R
S
S
P
L
H
L
Site 67
S579
L
S
K
S
P
S
R
S
S
P
L
H
L
N
V
Site 68
S580
S
K
S
P
S
R
S
S
P
L
H
L
N
V
N
Site 69
S594
N
T
G
F
Q
E
E
S
I
P
I
L
T
R
P
Site 70
S611
P
L
V
K
L
Q
V
S
P
D
T
E
G
G
T
Site 71
T614
K
L
Q
V
S
P
D
T
E
G
G
T
C
I
R
Site 72
S638
L
Q
K
G
K
H
V
S
Q
N
K
E
E
D
D
Site 73
T674
G
E
P
G
V
V
L
T
K
S
T
S
L
P
S
Site 74
S681
T
K
S
T
S
L
P
S
L
S
Q
L
E
L
D
Site 75
S683
S
T
S
L
P
S
L
S
Q
L
E
L
D
K
E
Site 76
S709
R
P
I
L
R
R
I
S
H
I
G
E
T
V
H
Site 77
T714
R
I
S
H
I
G
E
T
V
H
R
E
S
V
V
Site 78
S719
G
E
T
V
H
R
E
S
V
V
G
D
I
P
K
Site 79
T752
K
I
I
D
M
R
G
T
D
I
T
L
K
S
K
Site 80
T755
D
M
R
G
T
D
I
T
L
K
S
K
K
S
P
Site 81
S758
G
T
D
I
T
L
K
S
K
K
S
P
R
S
C
Site 82
S761
I
T
L
K
S
K
K
S
P
R
S
C
M
L
H
Site 83
S764
K
S
K
K
S
P
R
S
C
M
L
H
R
T
E
Site 84
S808
L
F
S
K
P
L
P
S
N
L
K
L
E
R
A
Site 85
T816
N
L
K
L
E
R
A
T
H
A
D
E
E
R
L
Site 86
T827
E
E
R
L
G
G
K
T
S
F
V
L
P
L
M
Site 87
S862
R
K
G
K
P
H
R
S
Q
K
E
N
R
H
E
Site 88
T872
E
N
R
H
E
V
K
T
I
D
M
R
F
R
I
Site 89
S887
H
C
Q
E
A
R
I
S
P
M
S
H
I
L
N
Site 90
S890
E
A
R
I
S
P
M
S
H
I
L
N
A
K
E
Site 91
Y934
I
P
S
A
P
P
L
Y
L
D
S
G
N
K
T
Site 92
S937
A
P
P
L
Y
L
D
S
G
N
K
T
D
K
D
Site 93
T941
Y
L
D
S
G
N
K
T
D
K
D
T
P
G
I
Site 94
T945
G
N
K
T
D
K
D
T
P
G
I
T
G
S
S
Site 95
S951
D
T
P
G
I
T
G
S
S
C
P
Q
R
T
L
Site 96
S952
T
P
G
I
T
G
S
S
C
P
Q
R
T
L
H
Site 97
T957
G
S
S
C
P
Q
R
T
L
H
V
P
S
N
T
Site 98
T968
P
S
N
T
Q
K
I
T
N
R
D
S
V
E
G
Site 99
S972
Q
K
I
T
N
R
D
S
V
E
G
V
D
K
N
Site 100
Y987
V
V
K
Q
A
E
Q
Y
V
P
R
P
E
A
E
Site 101
T998
P
E
A
E
Q
Q
L
T
S
N
F
M
I
S
V
Site 102
S1012
V
Q
Q
R
N
Q
P
S
R
V
R
S
E
E
D
Site 103
S1016
N
Q
P
S
R
V
R
S
E
E
D
L
N
Q
L
Site 104
Y1033
N
S
R
D
E
D
I
Y
F
T
G
F
G
T
I
Site 105
T1039
I
Y
F
T
G
F
G
T
I
R
S
G
K
R
P
Site 106
S1042
T
G
F
G
T
I
R
S
G
K
R
P
E
W
L
Site 107
T1051
K
R
P
E
W
L
F
T
G
K
K
A
Q
P
V
Site 108
T1064
P
V
K
Y
K
T
E
T
L
T
A
F
L
S
Y
Site 109
T1066
K
Y
K
T
E
T
L
T
A
F
L
S
Y
P
T
Site 110
T1077
S
Y
P
T
M
D
A
T
K
M
G
G
L
E
E
Site 111
S1097
D
N
L
N
H
K
I
S
P
K
A
S
V
S
L
Site 112
S1101
H
K
I
S
P
K
A
S
V
S
L
I
R
K
I
Site 113
S1103
I
S
P
K
A
S
V
S
L
I
R
K
I
S
K
Site 114
Y1113
R
K
I
S
K
E
L
Y
V
T
L
G
T
P
A
Site 115
T1115
I
S
K
E
L
Y
V
T
L
G
T
P
A
N
S
Site 116
T1118
E
L
Y
V
T
L
G
T
P
A
N
S
K
G
F
Site 117
S1122
T
L
G
T
P
A
N
S
K
G
F
S
V
S
E
Site 118
S1126
P
A
N
S
K
G
F
S
V
S
E
R
Y
A
H
Site 119
S1128
N
S
K
G
F
S
V
S
E
R
Y
A
H
Q
Q
Site 120
S1138
Y
A
H
Q
Q
E
T
S
S
K
V
S
P
E
L
Site 121
S1142
Q
E
T
S
S
K
V
S
P
E
L
A
G
S
C
Site 122
S1148
V
S
P
E
L
A
G
S
C
K
F
D
K
P
K
Site 123
S1160
K
P
K
E
D
G
Q
S
N
D
R
I
S
K
M
Site 124
S1165
G
Q
S
N
D
R
I
S
K
M
F
S
P
K
V
Site 125
S1169
D
R
I
S
K
M
F
S
P
K
V
L
A
P
Q
Site 126
T1217
R
C
E
H
G
H
K
T
R
T
N
T
I
L
S
Site 127
T1219
E
H
G
H
K
T
R
T
N
T
I
L
S
K
F
Site 128
T1221
G
H
K
T
R
T
N
T
I
L
S
K
F
P
L
Site 129
S1224
T
R
T
N
T
I
L
S
K
F
P
L
Q
S
G
Site 130
S1230
L
S
K
F
P
L
Q
S
G
K
Q
K
T
P
S
Site 131
T1235
L
Q
S
G
K
Q
K
T
P
S
E
T
D
V
D
Site 132
S1237
S
G
K
Q
K
T
P
S
E
T
D
V
D
K
K
Site 133
T1245
E
T
D
V
D
K
K
T
T
A
H
L
S
L
Q
Site 134
S1250
K
K
T
T
A
H
L
S
L
Q
M
L
P
G
I
Site 135
T1262
P
G
I
H
M
D
M
T
E
I
D
P
A
K
G
Site 136
S1278
R
K
Q
A
L
L
I
S
E
Q
E
E
G
V
L
Site 137
T1297
K
S
L
F
P
P
W
T
F
Q
F
Q
S
G
D
Site 138
T1311
D
L
E
E
K
H
Q
T
D
A
N
T
N
I
N
Site 139
S1330
K
L
E
M
D
N
D
S
T
V
N
Q
K
E
G
Site 140
T1331
L
E
M
D
N
D
S
T
V
N
Q
K
E
G
K
Site 141
T1343
E
G
K
L
K
I
G
T
N
R
A
L
H
L
Q
Site 142
T1354
L
H
L
Q
E
E
K
T
E
M
H
K
A
R
T
Site 143
T1361
T
E
M
H
K
A
R
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S2433
S
S
S
W
N
I
W
S
S
S
K
K
L
L
G
Site 296
S2434
S
S
W
N
I
W
S
S
S
K
K
L
L
G
S
Site 297
S2435
S
W
N
I
W
S
S
S
K
K
L
L
G
S
L
Site 298
S2441
S
S
K
K
L
L
G
S
L
S
G
S
L
T
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation