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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPFIBP2
Full Name:
Liprin-beta-2
Alias:
Cclp1; LIPB2; liprin beta 2; liprin-beta-2; protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF interacting protein, binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
Type:
Adaptor/scaffold
Mass (Da):
98445
Number AA:
876
UniProt ID:
Q8ND30
International Prot ID:
IPI00301689
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008907
PhosphoSite+
KinaseNET
Biological Process:
GO:0015074
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
D
A
S
H
A
L
E
Site 2
S30
T
K
T
G
A
D
L
S
D
G
T
C
E
P
G
Site 3
T33
G
A
D
L
S
D
G
T
C
E
P
G
L
A
S
Site 4
S40
T
C
E
P
G
L
A
S
P
A
S
Y
M
N
P
Site 5
S75
Q
E
R
A
A
L
L
S
Q
I
P
G
P
T
A
Site 6
T81
L
S
Q
I
P
G
P
T
A
A
Y
I
K
E
W
Site 7
Y84
I
P
G
P
T
A
A
Y
I
K
E
W
F
E
E
Site 8
S94
E
W
F
E
E
S
L
S
Q
V
N
H
H
S
A
Site 9
S100
L
S
Q
V
N
H
H
S
A
A
S
N
E
T
Y
Site 10
Y107
S
A
A
S
N
E
T
Y
Q
E
R
L
A
R
L
Site 11
S120
R
L
E
G
D
K
E
S
L
I
L
Q
V
S
V
Site 12
S166
M
L
Q
Q
E
L
L
S
R
T
S
L
E
T
Q
Site 13
S169
Q
E
L
L
S
R
T
S
L
E
T
Q
K
L
D
Site 14
T172
L
S
R
T
S
L
E
T
Q
K
L
D
L
M
T
Site 15
T179
T
Q
K
L
D
L
M
T
E
V
S
E
L
K
L
Site 16
S182
L
D
L
M
T
E
V
S
E
L
K
L
K
L
V
Site 17
Y229
L
E
N
E
R
N
Q
Y
E
W
K
L
K
A
T
Site 18
S259
A
E
I
E
R
L
H
S
Q
L
S
R
T
A
A
Site 19
S262
E
R
L
H
S
Q
L
S
R
T
A
A
L
H
S
Site 20
S269
S
R
T
A
A
L
H
S
E
S
H
T
E
R
D
Site 21
T273
A
L
H
S
E
S
H
T
E
R
D
Q
E
I
Q
Site 22
T304
D
R
R
I
E
E
L
T
G
L
L
N
Q
Y
R
Site 23
Y310
L
T
G
L
L
N
Q
Y
R
K
V
K
E
I
V
Site 24
T320
V
K
E
I
V
M
V
T
Q
G
P
S
E
R
T
Site 25
S324
V
M
V
T
Q
G
P
S
E
R
T
L
S
I
N
Site 26
S329
G
P
S
E
R
T
L
S
I
N
E
E
E
P
E
Site 27
S340
E
E
P
E
G
G
F
S
K
W
N
A
T
N
K
Site 28
S362
Q
E
M
P
P
R
C
S
S
P
T
V
G
P
P
Site 29
S363
E
M
P
P
R
C
S
S
P
T
V
G
P
P
P
Site 30
T365
P
P
R
C
S
S
P
T
V
G
P
P
P
L
P
Site 31
S375
P
P
P
L
P
Q
K
S
L
E
T
R
A
Q
K
Site 32
S385
T
R
A
Q
K
K
L
S
C
S
L
E
D
L
R
Site 33
S387
A
Q
K
K
L
S
C
S
L
E
D
L
R
S
E
Site 34
S393
C
S
L
E
D
L
R
S
E
S
V
D
K
C
M
Site 35
S395
L
E
D
L
R
S
E
S
V
D
K
C
M
D
G
Site 36
S414
P
V
L
E
P
K
D
S
P
F
L
A
E
H
K
Site 37
Y422
P
F
L
A
E
H
K
Y
P
T
L
P
G
K
L
Site 38
T424
L
A
E
H
K
Y
P
T
L
P
G
K
L
S
G
Site 39
S430
P
T
L
P
G
K
L
S
G
A
T
P
N
G
E
Site 40
T433
P
G
K
L
S
G
A
T
P
N
G
E
A
A
K
Site 41
S441
P
N
G
E
A
A
K
S
P
P
T
I
C
Q
P
Site 42
T444
E
A
A
K
S
P
P
T
I
C
Q
P
D
A
T
Site 43
S454
Q
P
D
A
T
G
S
S
L
L
R
L
R
D
T
Site 44
T461
S
L
L
R
L
R
D
T
E
S
G
W
D
D
T
Site 45
S463
L
R
L
R
D
T
E
S
G
W
D
D
T
A
V
Site 46
T468
T
E
S
G
W
D
D
T
A
V
V
N
D
L
S
Site 47
S475
T
A
V
V
N
D
L
S
S
T
S
S
G
T
E
Site 48
S476
A
V
V
N
D
L
S
S
T
S
S
G
T
E
S
Site 49
S479
N
D
L
S
S
T
S
S
G
T
E
S
G
P
Q
Site 50
S483
S
T
S
S
G
T
E
S
G
P
Q
S
P
L
T
Site 51
S487
G
T
E
S
G
P
Q
S
P
L
T
P
D
G
K
Site 52
T490
S
G
P
Q
S
P
L
T
P
D
G
K
R
N
P
Site 53
T510
F
W
G
K
I
R
R
T
Q
S
G
N
F
Y
T
Site 54
S512
G
K
I
R
R
T
Q
S
G
N
F
Y
T
D
T
Site 55
Y516
R
T
Q
S
G
N
F
Y
T
D
T
L
G
M
A
Site 56
T519
S
G
N
F
Y
T
D
T
L
G
M
A
E
F
R
Site 57
T533
R
R
G
G
L
R
A
T
A
G
P
R
L
S
R
Site 58
S539
A
T
A
G
P
R
L
S
R
T
R
D
S
K
G
Site 59
T541
A
G
P
R
L
S
R
T
R
D
S
K
G
Q
K
Site 60
S544
R
L
S
R
T
R
D
S
K
G
Q
K
S
D
A
Site 61
S549
R
D
S
K
G
Q
K
S
D
A
N
A
P
F
A
Site 62
S585
F
A
R
Q
W
V
S
S
G
H
T
L
L
T
A
Site 63
T588
Q
W
V
S
S
G
H
T
L
L
T
A
T
P
Q
Site 64
T591
S
S
G
H
T
L
L
T
A
T
P
Q
D
M
E
Site 65
T593
G
H
T
L
L
T
A
T
P
Q
D
M
E
K
E
Site 66
Y647
D
D
I
G
L
P
Q
Y
K
D
Q
F
H
E
S
Site 67
Y663
V
D
G
R
M
L
Q
Y
L
T
V
N
D
L
L
Site 68
S708
H
R
R
P
A
D
E
S
N
L
S
P
S
E
V
Site 69
S711
P
A
D
E
S
N
L
S
P
S
E
V
V
Q
W
Site 70
S713
D
E
S
N
L
S
P
S
E
V
V
Q
W
S
N
Site 71
S729
R
V
M
E
W
L
R
S
V
D
L
A
E
Y
A
Site 72
Y735
R
S
V
D
L
A
E
Y
A
P
N
L
R
G
S
Site 73
T771
L
N
I
P
P
Q
K
T
L
L
R
R
H
L
T
Site 74
S799
E
K
R
E
K
M
A
S
P
A
Y
T
P
L
T
Site 75
T803
K
M
A
S
P
A
Y
T
P
L
T
T
T
A
K
Site 76
T806
S
P
A
Y
T
P
L
T
T
T
A
K
V
R
P
Site 77
S819
R
P
R
K
L
G
F
S
H
F
G
N
I
R
K
Site 78
Y835
K
F
D
E
S
T
D
Y
I
C
P
M
E
P
S
Site 79
S842
Y
I
C
P
M
E
P
S
D
G
V
S
D
S
H
Site 80
S846
M
E
P
S
D
G
V
S
D
S
H
R
V
Y
S
Site 81
S848
P
S
D
G
V
S
D
S
H
R
V
Y
S
G
Y
Site 82
Y852
V
S
D
S
H
R
V
Y
S
G
Y
R
G
L
S
Site 83
S853
S
D
S
H
R
V
Y
S
G
Y
R
G
L
S
P
Site 84
Y855
S
H
R
V
Y
S
G
Y
R
G
L
S
P
L
D
Site 85
S859
Y
S
G
Y
R
G
L
S
P
L
D
A
P
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation