PhosphoNET

           
Protein Info 
   
Short Name:  ZNRF1
Full Name:  E3 ubiquitin-protein ligase ZNRF1
Alias:  DKFZp434E229; FLJ14846; Nerve injury-induced 283; Nerve injury-induced gene 283 protein; NIN283; Zinc and ring finger 1; Zinc/RING finger protein 1
Type:  EC 6.3.2.-; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Mass (Da):  23783
Number AA:  227
UniProt ID:  Q8ND25
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0031410  GO:0005768 Uniprot OncoNet
Molecular Function:  GO:0016874  GO:0005515  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0019941     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MGGKQSTAARSRG
Site 2T7_MGGKQSTAARSRGP
Site 3S11KQSTAARSRGPFPGV
Site 4S19RGPFPGVSTDDSAVP
Site 5S23PGVSTDDSAVPPPGG
Site 6Y37GAPHFGHYRTGGGAM
Site 7S48GGAMGLRSRSVSSVA
Site 8S50AMGLRSRSVSSVAGM
Site 9S52GLRSRSVSSVAGMGM
Site 10S53LRSRSVSSVAGMGMD
Site 11Y72GGVPFGLYTPASRGT
Site 12T73GVPFGLYTPASRGTG
Site 13S76FGLYTPASRGTGDSE
Site 14T79YTPASRGTGDSERAP
Site 15S82ASRGTGDSERAPGGG
Site 16S91RAPGGGGSASDSTYA
Site 17S93PGGGGSASDSTYAHG
Site 18S95GGGSASDSTYAHGNG
Site 19T96GGSASDSTYAHGNGY
Site 20Y97GSASDSTYAHGNGYQ
Site 21Y103TYAHGNGYQETGGGH
Site 22T106HGNGYQETGGGHHRD
Site 23Y117HHRDGMLYLGSRASL
Site 24S123LYLGSRASLADALPL
Site 25S149GFKCPICSKSVASDE
Site 26S151KCPICSKSVASDEME
Site 27S154ICSKSVASDEMEMHF
Site 28S171CLSKPRLSYNDDVLT
Site 29Y172LSKPRLSYNDDVLTK
Site 30T178SYNDDVLTKDAGECV
Site 31S220SWFEVNRSCPEHPAD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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