PhosphoNET

           
Protein Info 
   
Short Name:  SPRYD3
Full Name:  SPRY domain-containing protein 3
Alias:  SPRY3
Type: 
Mass (Da):  49694
Number AA:  442
UniProt ID:  Q8NCJ5
International Prot ID:  IPI00385992
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y22MDDLNLHYRFLNWRR
Site 2Y42REVRAFRYQERFKHI
Site 3T55HILVDGDTLSYHGNS
Site 4S57LVDGDTLSYHGNSGE
Site 5Y58VDGDTLSYHGNSGEV
Site 6Y68NSGEVGCYVASRPLT
Site 7S71EVGCYVASRPLTKDS
Site 8T75YVASRPLTKDSNYFE
Site 9S78SRPLTKDSNYFEVSI
Site 10Y80PLTKDSNYFEVSIVD
Site 11S84DSNYFEVSIVDSGVR
Site 12Y102AVGLVPQYYSLDHQP
Site 13Y103VGLVPQYYSLDHQPG
Site 14S104GLVPQYYSLDHQPGW
Site 15S115QPGWLPDSVAYHADD
Site 16Y126HADDGKLYNGRAKGR
Site 17S137AKGRQFGSKCNSGDR
Site 18S141QFGSKCNSGDRIGCG
Site 19S172KNGKRVGSTIMPMSP
Site 20T173NGKRVGSTIMPMSPD
Site 21S209ELGREDDSVMMVDSY
Site 22S215DSVMMVDSYEDEWGR
Site 23Y216SVMMVDSYEDEWGRL
Site 24S255AQARHPLSTRSHYFE
Site 25T256QARHPLSTRSHYFEV
Site 26Y260PLSTRSHYFEVEIVD
Site 27Y283LGLARKDYPKNRHPG
Site 28S292KNRHPGWSRGSVAYH
Site 29S295HPGWSRGSVAYHADD
Site 30Y298WSRGSVAYHADDGKI
Site 31S309DGKIFHGSGVGDPFG
Site 32Y335GIMFPRDYILDSEGD
Site 33S339PRDYILDSEGDSDDS
Site 34S343ILDSEGDSDDSCDTV
Site 35S346SEGDSDDSCDTVILS
Site 36T349DSDDSCDTVILSPTA
Site 37Y367RNVRNVMYLHQEGEE
Site 38S441KVDLHPLSG______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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