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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LEMD2
Full Name:
LEM domain-containing protein 2
Alias:
DJ482C21.1; LEM domain containing 2; LEM domain-containing protein 2: Putative uncharacterized protein LEMD2; NET25
Type:
Uncharacterized protein
Mass (Da):
56975
Number AA:
503
UniProt ID:
Q8NC56
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005639
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
G
F
Q
P
G
P
I
T
D
T
T
R
D
V
Y
Site 2
T26
Q
P
G
P
I
T
D
T
T
R
D
V
Y
R
N
Site 3
T27
P
G
P
I
T
D
T
T
R
D
V
Y
R
N
K
Site 4
Y31
T
D
T
T
R
D
V
Y
R
N
K
L
R
R
L
Site 5
S82
R
A
R
P
A
A
A
S
P
R
A
E
P
W
L
Site 6
S90
P
R
A
E
P
W
L
S
Q
P
A
S
G
S
A
Site 7
S94
P
W
L
S
Q
P
A
S
G
S
A
Y
A
T
P
Site 8
S96
L
S
Q
P
A
S
G
S
A
Y
A
T
P
G
A
Site 9
Y98
Q
P
A
S
G
S
A
Y
A
T
P
G
A
Y
G
Site 10
T100
A
S
G
S
A
Y
A
T
P
G
A
Y
G
D
I
Site 11
Y104
A
Y
A
T
P
G
A
Y
G
D
I
R
P
S
A
Site 12
S110
A
Y
G
D
I
R
P
S
A
A
S
W
V
G
S
Site 13
S113
D
I
R
P
S
A
A
S
W
V
G
S
R
G
L
Site 14
Y122
V
G
S
R
G
L
A
Y
P
A
R
P
A
Q
L
Site 15
S134
A
Q
L
R
R
R
A
S
V
R
G
S
S
E
E
Site 16
S138
R
R
A
S
V
R
G
S
S
E
E
D
E
D
A
Site 17
S139
R
A
S
V
R
G
S
S
E
E
D
E
D
A
R
Site 18
T147
E
E
D
E
D
A
R
T
P
D
R
A
T
Q
G
Site 19
T152
A
R
T
P
D
R
A
T
Q
G
P
G
L
A
A
Site 20
S166
A
R
R
W
W
A
A
S
P
A
P
A
R
L
P
Site 21
S174
P
A
P
A
R
L
P
S
S
L
L
G
P
D
P
Site 22
S175
A
P
A
R
L
P
S
S
L
L
G
P
D
P
R
Site 23
T188
P
R
P
G
L
R
A
T
R
A
G
P
A
G
A
Site 24
S211
R
R
L
E
R
W
L
S
R
L
L
L
W
A
S
Site 25
T257
P
V
D
C
E
R
K
T
D
E
F
C
Q
A
K
Site 26
S297
G
N
P
E
N
L
K
S
K
C
I
P
V
M
E
Site 27
Y308
P
V
M
E
A
Q
E
Y
I
A
N
V
T
S
S
Site 28
T313
Q
E
Y
I
A
N
V
T
S
S
S
S
A
K
F
Site 29
S344
W
L
K
G
E
D
Q
S
E
L
V
T
T
V
D
Site 30
T348
E
D
Q
S
E
L
V
T
T
V
D
K
V
V
C
Site 31
Y399
G
L
L
I
L
L
K
Y
R
W
R
K
L
E
E
Site 32
Y412
E
E
E
E
Q
A
M
Y
E
M
V
K
K
I
I
Site 33
Y426
I
D
V
V
Q
D
H
Y
V
D
W
E
Q
D
M
Site 34
Y436
W
E
Q
D
M
E
R
Y
P
Y
V
G
I
L
H
Site 35
Y438
Q
D
M
E
R
Y
P
Y
V
G
I
L
H
V
R
Site 36
S447
G
I
L
H
V
R
D
S
L
I
P
P
Q
S
R
Site 37
S453
D
S
L
I
P
P
Q
S
R
R
R
M
K
R
V
Site 38
S470
R
A
V
E
F
L
A
S
N
E
S
R
I
Q
T
Site 39
S473
E
F
L
A
S
N
E
S
R
I
Q
T
E
S
H
Site 40
T477
S
N
E
S
R
I
Q
T
E
S
H
R
V
A
G
Site 41
S479
E
S
R
I
Q
T
E
S
H
R
V
A
G
E
D
Site 42
T493
D
M
L
V
W
R
W
T
K
P
S
S
F
S
D
Site 43
S496
V
W
R
W
T
K
P
S
S
F
S
D
S
E
R
Site 44
S497
W
R
W
T
K
P
S
S
F
S
D
S
E
R
_
Site 45
S499
W
T
K
P
S
S
F
S
D
S
E
R
_
_
_
Site 46
S501
K
P
S
S
F
S
D
S
E
R
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation