PhosphoNET

           
Protein Info 
   
Short Name:  RNF149
Full Name:  E3 ubiquitin-protein ligase RNF149
Alias:  DNA polymerase-transactivated protein 2;RING finger protein 149
Type: 
Mass (Da):  43165
Number AA:  400
UniProt ID:  Q8NC42
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9AWRRREASVGARGVL
Site 2Y46SAVVNIEYVDPQTNL
Site 3T51IEYVDPQTNLTVWSV
Site 4T54VDPQTNLTVWSVSES
Site 5S57QTNLTVWSVSESGRF
Site 6S59NLTVWSVSESGRFGD
Site 7S61TVWSVSESGRFGDSS
Site 8S67ESGRFGDSSPKEGAH
Site 9S68SGRFGDSSPKEGAHG
Site 10T94LEGCAPDTRFFVPEP
Site 11T147EERYGNITLPMSHAG
Site 12S151GNITLPMSHAGTGNI
Site 13Y229YYIQRFLYTGSQIGS
Site 14S232QRFLYTGSQIGSQSH
Site 15S236YTGSQIGSQSHRKET
Site 16S238GSQIGSQSHRKETKK
Site 17T243SQSHRKETKKVIGQL
Site 18T254IGQLLLHTVKHGEKG
Site 19S334QEMPAPESPPGRDPA
Site 20S345RDPAANLSLALPDDD
Site 21S354ALPDDDGSDDSSPPS
Site 22S357DDDGSDDSSPPSASP
Site 23S358DDGSDDSSPPSASPA
Site 24S361SDDSSPPSASPAESE
Site 25S363DSSPPSASPAESEPQ
Site 26S367PSASPAESEPQCDPS
Site 27S374SEPQCDPSFKGDAGE
Site 28S391ALLEAGRSDSRHGGP
Site 29S393LEAGRSDSRHGGPIS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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