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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD52
Full Name:
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Alias:
Ankyrin repeat domain 52; ANR52; FLJ34236; PP6-ARS-C; Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Type:
Unknown function
Mass (Da):
115058
Number AA:
1076
UniProt ID:
Q8NB46
International Prot ID:
IPI00398957
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
G
I
L
S
I
T
D
Q
P
P
L
Site 2
T7
_
M
G
I
L
S
I
T
D
Q
P
P
L
V
Q
Site 3
S18
P
L
V
Q
A
I
F
S
R
D
V
E
E
V
R
Site 4
S26
R
D
V
E
E
V
R
S
L
L
S
Q
K
E
N
Site 5
S29
E
E
V
R
S
L
L
S
Q
K
E
N
I
N
V
Site 6
T43
V
L
D
Q
E
R
R
T
P
L
H
A
A
A
Y
Site 7
T72
A
N
V
N
A
K
D
T
L
W
L
T
P
L
H
Site 8
T76
A
K
D
T
L
W
L
T
P
L
H
R
A
A
A
Site 9
T109
A
R
D
K
L
W
Q
T
P
L
H
V
A
A
A
Site 10
S139
S
L
N
V
A
D
R
S
G
R
S
A
L
H
H
Site 11
S165
L
L
L
N
K
G
A
S
L
N
V
C
D
K
K
Site 12
Y207
G
C
K
D
R
K
G
Y
G
L
L
H
T
A
A
Site 13
T274
Q
P
N
D
K
G
F
T
P
L
H
V
A
A
V
Site 14
Y301
N
N
G
A
D
V
N
Y
Q
V
P
E
G
K
S
Site 15
S308
Y
Q
V
P
E
G
K
S
P
L
H
M
A
A
I
Site 16
S322
I
H
G
R
F
T
R
S
Q
I
L
I
Q
N
G
Site 17
S330
Q
I
L
I
Q
N
G
S
E
I
D
C
A
D
K
Site 18
T341
C
A
D
K
F
G
N
T
P
L
H
V
A
A
R
Site 19
T365
L
M
T
N
G
A
D
T
A
R
R
G
I
H
D
Site 20
S393
D
C
C
R
K
L
L
S
S
G
Q
L
Y
S
I
Site 21
Y398
L
L
S
S
G
Q
L
Y
S
I
V
S
S
L
S
Site 22
S402
G
Q
L
Y
S
I
V
S
S
L
S
N
E
H
V
Site 23
T418
S
A
G
F
D
I
N
T
P
D
N
L
G
R
T
Site 24
S444
E
C
L
N
L
L
L
S
S
G
A
D
L
R
R
Site 25
T458
R
R
D
K
F
G
R
T
P
L
H
Y
A
A
A
Site 26
Y462
F
G
R
T
P
L
H
Y
A
A
A
N
G
S
Y
Site 27
S491
E
A
D
C
K
G
C
S
P
L
H
Y
A
A
A
Site 28
Y495
K
G
C
S
P
L
H
Y
A
A
A
S
D
T
Y
Site 29
S499
P
L
H
Y
A
A
A
S
D
T
Y
R
R
A
E
Site 30
T501
H
Y
A
A
A
S
D
T
Y
R
R
A
E
P
H
Site 31
Y502
Y
A
A
A
S
D
T
Y
R
R
A
E
P
H
T
Site 32
T509
Y
R
R
A
E
P
H
T
P
S
S
H
D
A
E
Site 33
S512
A
E
P
H
T
P
S
S
H
D
A
E
E
D
E
Site 34
S544
L
D
N
G
A
D
P
S
L
R
D
R
Q
G
Y
Site 35
Y551
S
L
R
D
R
Q
G
Y
T
A
V
H
Y
A
A
Site 36
Y556
Q
G
Y
T
A
V
H
Y
A
A
A
Y
G
N
R
Site 37
T626
R
T
A
L
F
L
A
T
E
R
G
S
T
E
C
Site 38
T654
K
E
R
K
R
K
W
T
P
L
H
A
A
A
A
Site 39
S667
A
A
S
G
H
T
D
S
L
H
L
L
I
D
S
Site 40
S674
S
L
H
L
L
I
D
S
G
E
R
A
D
I
T
Site 41
T681
S
G
E
R
A
D
I
T
D
V
M
D
A
Y
G
Site 42
T713
L
L
L
E
K
G
S
T
A
D
A
A
D
L
R
Site 43
T723
A
A
D
L
R
G
R
T
A
L
H
R
G
A
V
Site 44
T756
C
R
D
F
K
G
R
T
P
I
H
L
A
S
A
Site 45
Y789
P
L
D
A
G
V
D
Y
S
G
Y
S
P
M
H
Site 46
Y792
A
G
V
D
Y
S
G
Y
S
P
M
H
W
A
S
Site 47
S817
L
L
E
H
S
P
F
S
Y
L
E
G
N
P
F
Site 48
Y818
L
E
H
S
P
F
S
Y
L
E
G
N
P
F
T
Site 49
T838
V
I
N
N
Q
D
S
T
T
E
M
L
L
G
A
Site 50
T839
I
N
N
Q
D
S
T
T
E
M
L
L
G
A
L
Site 51
S853
L
G
A
K
I
V
N
S
R
D
A
K
G
R
T
Site 52
T860
S
R
D
A
K
G
R
T
P
L
H
A
A
A
F
Site 53
T887
H
Q
A
E
V
N
A
T
D
H
T
G
R
T
A
Site 54
T890
E
V
N
A
T
D
H
T
G
R
T
A
L
M
T
Site 55
T897
T
G
R
T
A
L
M
T
A
A
E
N
G
Q
T
Site 56
T904
T
A
A
E
N
G
Q
T
A
A
V
E
F
L
L
Site 57
Y912
A
A
V
E
F
L
L
Y
R
G
K
A
D
L
T
Site 58
T919
Y
R
G
K
A
D
L
T
V
L
D
E
N
K
N
Site 59
T927
V
L
D
E
N
K
N
T
A
L
H
L
A
C
S
Site 60
S934
T
A
L
H
L
A
C
S
K
G
H
E
K
C
A
Site 61
T996
A
V
D
E
E
G
H
T
P
A
L
A
C
A
P
Site 62
S1016
D
C
L
A
L
I
L
S
T
M
K
P
F
P
P
Site 63
T1017
C
L
A
L
I
L
S
T
M
K
P
F
P
P
K
Site 64
S1028
F
P
P
K
D
A
V
S
P
F
S
F
S
L
L
Site 65
S1031
K
D
A
V
S
P
F
S
F
S
L
L
K
N
C
Site 66
S1057
G
A
L
P
H
G
A
S
C
P
Y
S
Q
E
R
Site 67
S1061
H
G
A
S
C
P
Y
S
Q
E
R
P
G
A
I
Site 68
Y1074
A
I
G
L
D
G
C
Y
S
E
_
_
_
_
_
Site 69
S1075
I
G
L
D
G
C
Y
S
E
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation