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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF527
Full Name:
Zinc finger protein 527
Alias:
Type:
Mass (Da):
67334
Number AA:
577
UniProt ID:
Q8NB42
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
R
D
V
A
L
D
F
S
Q
E
E
W
E
W
L
Site 2
Y39
K
P
S
Q
K
D
L
Y
R
D
V
M
L
E
N
Site 3
Y47
R
D
V
M
L
E
N
Y
R
N
L
V
W
L
D
Site 4
S76
F
I
D
E
D
E
I
S
Q
E
M
V
M
E
R
Site 5
S86
M
V
M
E
R
L
A
S
H
G
L
E
C
S
S
Site 6
S92
A
S
H
G
L
E
C
S
S
F
R
E
A
W
K
Site 7
S93
S
H
G
L
E
C
S
S
F
R
E
A
W
K
Y
Site 8
Y100
S
F
R
E
A
W
K
Y
K
G
E
F
E
L
H
Site 9
S134
G
K
R
D
N
E
F
S
N
S
G
R
S
I
P
Site 10
S136
R
D
N
E
F
S
N
S
G
R
S
I
P
L
K
Site 11
S139
E
F
S
N
S
G
R
S
I
P
L
K
S
V
F
Site 12
S144
G
R
S
I
P
L
K
S
V
F
L
T
Q
Q
K
Site 13
Y164
Q
V
H
K
F
D
I
Y
D
K
L
F
P
Q
N
Site 14
S172
D
K
L
F
P
Q
N
S
V
I
I
E
Y
K
R
Site 15
S198
E
C
E
E
F
N
Q
S
T
Y
L
S
K
D
I
Site 16
Y200
E
E
F
N
Q
S
T
Y
L
S
K
D
I
G
I
Site 17
S202
F
N
Q
S
T
Y
L
S
K
D
I
G
I
P
P
Site 18
Y214
I
P
P
G
E
K
P
Y
E
S
H
D
F
S
K
Site 19
S216
P
G
E
K
P
Y
E
S
H
D
F
S
K
L
L
Site 20
S220
P
Y
E
S
H
D
F
S
K
L
L
S
F
H
S
Site 21
S224
H
D
F
S
K
L
L
S
F
H
S
L
F
T
Q
Site 22
S227
S
K
L
L
S
F
H
S
L
F
T
Q
H
Q
T
Site 23
Y244
F
G
K
L
P
H
G
Y
D
E
C
G
D
A
F
Site 24
Y254
C
G
D
A
F
S
C
Y
S
F
F
T
Q
P
Q
Site 25
S255
G
D
A
F
S
C
Y
S
F
F
T
Q
P
Q
R
Site 26
S265
T
Q
P
Q
R
I
H
S
G
E
K
P
Y
A
C
Site 27
S280
N
D
C
G
K
A
F
S
H
D
F
F
L
S
E
Site 28
T291
F
L
S
E
H
Q
R
T
H
I
G
E
K
P
Y
Site 29
Y298
T
H
I
G
E
K
P
Y
E
C
K
E
C
N
K
Site 30
T321
A
Q
H
Q
R
I
H
T
G
E
K
P
F
A
C
Site 31
S336
N
E
C
G
K
A
F
S
R
Y
A
F
L
V
E
Site 32
Y338
C
G
K
A
F
S
R
Y
A
F
L
V
E
H
Q
Site 33
T349
V
E
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 34
Y354
I
H
T
G
E
K
P
Y
E
C
K
E
C
N
K
Site 35
T377
N
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 36
Y382
I
H
T
G
E
K
P
Y
E
C
N
Q
C
G
K
Site 37
S392
N
Q
C
G
K
A
F
S
R
R
I
A
L
T
L
Site 38
T398
F
S
R
R
I
A
L
T
L
H
Q
R
I
H
T
Site 39
T405
T
L
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 40
S413
G
E
K
P
F
K
C
S
E
C
G
K
T
F
G
Site 41
T418
K
C
S
E
C
G
K
T
F
G
Y
R
S
H
L
Site 42
Y421
E
C
G
K
T
F
G
Y
R
S
H
L
N
Q
H
Site 43
S423
G
K
T
F
G
Y
R
S
H
L
N
Q
H
Q
R
Site 44
Y438
I
H
T
G
E
K
P
Y
E
C
I
K
C
G
K
Site 45
T449
K
C
G
K
F
F
R
T
D
S
Q
L
N
R
H
Site 46
S451
G
K
F
F
R
T
D
S
Q
L
N
R
H
H
R
Site 47
T461
N
R
H
H
R
I
H
T
G
E
R
P
F
E
C
Site 48
S469
G
E
R
P
F
E
C
S
K
C
G
K
A
F
S
Site 49
Y494
S
H
A
G
E
K
P
Y
E
C
N
K
C
G
K
Site 50
S507
G
K
A
F
S
C
G
S
Y
L
N
Q
H
Q
R
Site 51
Y508
K
A
F
S
C
G
S
Y
L
N
Q
H
Q
R
I
Site 52
Y522
I
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 53
S536
K
A
F
H
Q
I
L
S
L
R
L
H
Q
R
I
Site 54
Y550
I
H
A
G
E
K
P
Y
K
C
N
E
C
G
N
Site 55
S560
N
E
C
G
N
N
F
S
C
V
S
A
L
R
R
Site 56
S563
G
N
N
F
S
C
V
S
A
L
R
R
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation