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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR21C
Full Name:
DDB1- and CUL4-associated factor 4-like protein 2
Alias:
WD repeat domain 21C; WD repeat-containing 21C; WD21C
Type:
Mass (Da):
43747
Number AA:
395
UniProt ID:
Q8NA75
International Prot ID:
IPI00167925
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
E
S
K
R
P
R
L
L
E
Site 2
T18
E
A
D
K
Q
K
K
T
V
R
V
G
L
N
A
Site 3
S52
I
A
R
E
L
R
V
S
C
M
Q
R
K
K
V
Site 4
S63
R
K
K
V
Q
I
H
S
W
D
P
S
S
L
A
Site 5
S67
Q
I
H
S
W
D
P
S
S
L
A
S
D
R
F
Site 6
S68
I
H
S
W
D
P
S
S
L
A
S
D
R
F
N
Site 7
S71
W
D
P
S
S
L
A
S
D
R
F
N
R
I
L
Site 8
T81
F
N
R
I
L
A
N
T
N
T
D
Q
L
F
T
Site 9
T83
R
I
L
A
N
T
N
T
D
Q
L
F
T
V
N
Site 10
Y99
V
E
A
G
G
S
K
Y
G
I
I
T
M
R
G
Site 11
T103
G
S
K
Y
G
I
I
T
M
R
G
L
T
T
P
Site 12
T109
I
T
M
R
G
L
T
T
P
E
L
R
V
Y
P
Site 13
Y115
T
T
P
E
L
R
V
Y
P
H
K
T
L
Y
V
Site 14
T119
L
R
V
Y
P
H
K
T
L
Y
V
P
N
R
K
Site 15
Y121
V
Y
P
H
K
T
L
Y
V
P
N
R
K
V
N
Site 16
S167
P
A
S
L
F
I
G
S
F
P
G
M
R
R
P
Site 17
S199
L
S
I
H
A
Y
H
S
F
S
T
G
L
S
Q
Site 18
S201
I
H
A
Y
H
S
F
S
T
G
L
S
Q
Q
V
Site 19
S205
H
S
F
S
T
G
L
S
Q
Q
V
L
L
T
N
Site 20
S220
V
V
T
G
H
Q
Q
S
F
G
T
S
S
D
V
Site 21
S224
H
Q
Q
S
F
G
T
S
S
D
V
L
A
Q
Q
Site 22
S225
Q
Q
S
F
G
T
S
S
D
V
L
A
Q
Q
F
Site 23
S275
S
H
D
S
A
V
T
S
L
Q
I
L
Q
D
G
Site 24
S287
Q
D
G
Q
F
L
V
S
S
D
M
T
G
T
I
Site 25
S288
D
G
Q
F
L
V
S
S
D
M
T
G
T
I
K
Site 26
Y317
G
H
V
N
N
S
A
Y
L
P
V
H
V
N
E
Site 27
Y337
A
A
V
G
Q
D
C
Y
T
R
I
W
S
L
R
Site 28
T350
L
R
H
G
H
L
L
T
T
I
P
S
P
Y
P
Site 29
S354
H
L
L
T
T
I
P
S
P
Y
P
A
S
E
N
Site 30
S359
I
P
S
P
Y
P
A
S
E
N
D
I
P
S
V
Site 31
S365
A
S
E
N
D
I
P
S
V
A
F
S
S
R
L
Site 32
S369
D
I
P
S
V
A
F
S
S
R
L
G
G
F
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation