KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
L3MBTL4
Full Name:
Lethal(3)malignant brain tumor-like protein 4
Alias:
Type:
Mass (Da):
71122
Number AA:
623
UniProt ID:
Q8NA19
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
R
K
L
N
M
D
S
K
E
R
L
D
Q
D
Site 2
S36
E
E
K
K
P
K
D
S
T
T
P
L
S
H
V
Site 3
T37
E
K
K
P
K
D
S
T
T
P
L
S
H
V
P
Site 4
T38
K
K
P
K
D
S
T
T
P
L
S
H
V
P
S
Site 5
S41
K
D
S
T
T
P
L
S
H
V
P
S
A
A
A
Site 6
S45
T
P
L
S
H
V
P
S
A
A
A
Q
G
A
W
Site 7
Y57
G
A
W
S
W
E
W
Y
L
K
E
Q
K
A
V
Site 8
S76
E
L
F
S
K
D
Q
S
F
P
E
H
E
N
G
Site 9
Y121
L
R
L
H
F
D
G
Y
L
S
C
Y
D
F
W
Site 10
S133
D
F
W
T
N
A
G
S
P
D
I
H
P
V
G
Site 11
Y165
D
K
F
V
W
M
D
Y
L
K
A
C
K
L
Q
Site 12
S183
K
K
L
F
R
N
R
S
P
N
G
P
M
S
K
Site 13
S189
R
S
P
N
G
P
M
S
K
E
F
Q
V
G
M
Site 14
Y263
T
L
I
A
P
Q
G
Y
P
N
P
E
N
F
S
Site 15
Y274
E
N
F
S
W
T
E
Y
L
E
A
T
Q
T
N
Site 16
T280
E
Y
L
E
A
T
Q
T
N
A
V
P
A
K
V
Site 17
S345
D
Y
W
V
E
A
D
S
P
D
I
H
P
I
G
Site 18
T381
P
G
Q
A
V
C
P
T
P
G
C
R
G
I
G
Site 19
Y395
G
H
I
R
G
P
R
Y
S
G
H
H
S
A
F
Site 20
S396
H
I
R
G
P
R
Y
S
G
H
H
S
A
F
G
Site 21
S400
P
R
Y
S
G
H
H
S
A
F
G
C
P
Y
S
Site 22
S407
S
A
F
G
C
P
Y
S
D
M
N
L
K
K
E
Site 23
T416
M
N
L
K
K
E
A
T
L
H
D
R
L
R
E
Site 24
T425
H
D
R
L
R
E
Q
T
Q
A
N
L
E
S
D
Site 25
S431
Q
T
Q
A
N
L
E
S
D
S
S
H
S
K
S
Site 26
S433
Q
A
N
L
E
S
D
S
S
H
S
K
S
K
S
Site 27
S434
A
N
L
E
S
D
S
S
H
S
K
S
K
S
L
Site 28
S436
L
E
S
D
S
S
H
S
K
S
K
S
L
C
S
Site 29
S438
S
D
S
S
H
S
K
S
K
S
L
C
S
L
N
Site 30
S440
S
S
H
S
K
S
K
S
L
C
S
L
N
F
N
Site 31
S443
S
K
S
K
S
L
C
S
L
N
F
N
G
K
H
Site 32
S455
G
K
H
E
K
V
N
S
Q
P
R
L
V
Q
Q
Site 33
S493
H
P
R
G
L
E
Y
S
V
E
Q
A
Q
Q
V
Site 34
S506
Q
V
L
H
Q
P
V
S
M
S
T
V
S
A
H
Site 35
S508
L
H
Q
P
V
S
M
S
T
V
S
A
H
P
F
Site 36
T509
H
Q
P
V
S
M
S
T
V
S
A
H
P
F
R
Site 37
T544
A
S
Q
V
A
R
W
T
V
D
E
V
A
E
F
Site 38
S554
E
V
A
E
F
V
Q
S
L
L
G
C
E
E
H
Site 39
S607
S
I
L
M
F
R
H
S
Q
E
L
P
E
E
D
Site 40
S617
L
P
E
E
D
I
A
S
D
Q
E
V
R
G
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation