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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD53
Full Name:
Ankyrin repeat domain-containing protein 53
Alias:
Type:
Mass (Da):
59531
Number AA:
530
UniProt ID:
Q8N9V6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
A
S
A
G
S
T
A
R
R
A
G
S
G
Site 2
S13
S
T
A
R
R
A
G
S
G
S
W
H
S
E
R
Site 3
S15
A
R
R
A
G
S
G
S
W
H
S
E
R
G
E
Site 4
S18
A
G
S
G
S
W
H
S
E
R
G
E
G
R
G
Site 5
T31
R
G
A
R
P
Q
P
T
P
S
G
S
M
Q
Q
Site 6
S33
A
R
P
Q
P
T
P
S
G
S
M
Q
Q
A
N
Site 7
T47
N
K
V
S
L
K
A
T
W
T
D
A
E
S
K
Site 8
T49
V
S
L
K
A
T
W
T
D
A
E
S
K
Q
P
Site 9
S53
A
T
W
T
D
A
E
S
K
Q
P
S
Q
P
L
Site 10
S57
D
A
E
S
K
Q
P
S
Q
P
L
P
D
L
A
Site 11
T72
D
H
L
S
A
Q
A
T
A
L
A
R
P
R
R
Site 12
S82
A
R
P
R
R
P
A
S
L
T
P
P
R
A
D
Site 13
T84
P
R
R
P
A
S
L
T
P
P
R
A
D
P
S
Site 14
S91
T
P
P
R
A
D
P
S
P
S
K
E
S
D
Q
Site 15
S93
P
R
A
D
P
S
P
S
K
E
S
D
Q
T
A
Site 16
T99
P
S
K
E
S
D
Q
T
A
I
D
Q
T
A
I
Site 17
T104
D
Q
T
A
I
D
Q
T
A
I
G
S
Y
Y
Q
Site 18
S130
L
R
F
C
L
N
Q
S
L
R
E
I
P
T
D
Site 19
T171
K
F
P
V
D
L
L
T
N
N
S
Q
T
P
L
Site 20
T208
G
A
D
L
N
A
Q
T
C
N
G
S
T
P
L
Site 21
T213
A
Q
T
C
N
G
S
T
P
L
H
L
A
A
R
Site 22
T280
K
D
F
A
R
E
M
T
K
M
K
M
F
K
S
Site 23
T290
K
M
F
K
S
Q
L
T
L
M
E
H
N
Y
L
Site 24
Y296
L
T
L
M
E
H
N
Y
L
I
E
Y
Q
K
E
Site 25
Y300
E
H
N
Y
L
I
E
Y
Q
K
E
H
K
I
L
Site 26
S325
G
K
L
H
P
G
H
S
L
V
S
N
T
K
Q
Site 27
T336
N
T
K
Q
A
R
A
T
A
L
S
K
T
P
E
Site 28
S339
Q
A
R
A
T
A
L
S
K
T
P
E
Q
R
E
Site 29
T341
R
A
T
A
L
S
K
T
P
E
Q
R
E
S
Q
Site 30
S347
K
T
P
E
Q
R
E
S
Q
R
S
R
S
F
H
Site 31
S350
E
Q
R
E
S
Q
R
S
R
S
F
H
P
S
V
Site 32
S352
R
E
S
Q
R
S
R
S
F
H
P
S
V
D
A
Site 33
S356
R
S
R
S
F
H
P
S
V
D
A
R
L
Q
C
Site 34
T368
L
Q
C
I
P
Q
P
T
E
M
P
K
P
I
Y
Site 35
Y375
T
E
M
P
K
P
I
Y
R
K
P
T
V
K
R
Site 36
T379
K
P
I
Y
R
K
P
T
V
K
R
P
T
M
W
Site 37
T384
K
P
T
V
K
R
P
T
M
W
N
V
S
N
N
Site 38
T397
N
N
P
A
R
P
P
T
T
Q
I
S
H
S
Q
Site 39
T398
N
P
A
R
P
P
T
T
Q
I
S
H
S
Q
G
Site 40
S401
R
P
P
T
T
Q
I
S
H
S
Q
G
I
R
L
Site 41
S403
P
T
T
Q
I
S
H
S
Q
G
I
R
L
G
V
Site 42
T415
L
G
V
H
P
D
P
T
P
E
H
D
F
S
S
Site 43
S421
P
T
P
E
H
D
F
S
S
F
L
E
V
R
P
Site 44
S422
T
P
E
H
D
F
S
S
F
L
E
V
R
P
D
Site 45
Y460
E
V
L
L
R
M
L
Y
P
R
V
W
P
Y
R
Site 46
Y466
L
Y
P
R
V
W
P
Y
R
M
K
V
P
Q
G
Site 47
Y475
M
K
V
P
Q
G
F
Y
P
I
S
M
R
E
V
Site 48
S478
P
Q
G
F
Y
P
I
S
M
R
E
V
P
R
K
Site 49
T492
K
R
H
L
G
D
N
T
F
W
T
D
T
L
A
Site 50
T522
R
S
H
Q
G
L
P
T
P
P
S
P
Q
T
N
Site 51
S525
Q
G
L
P
T
P
P
S
P
Q
T
N
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation