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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCAI
Full Name:
Protein SCAI
Alias:
C9orf126; CI126; FLJ11758; FLJ36664; MGC120525; MGC120526; MGC120528; NET40; Suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein
Type:
Transcription, coactivator/corepressor
Mass (Da):
70381
Number AA:
606
UniProt ID:
Q8N9R8
International Prot ID:
IPI00184376
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0035024
GO:0030336
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
R
Q
P
Q
Q
P
R
S
R
L
A
P
R
L
T
Site 2
T20
S
R
L
A
P
R
L
T
G
T
V
E
K
P
P
Site 3
T22
L
A
P
R
L
T
G
T
V
E
K
P
P
R
K
Site 4
S32
K
P
P
R
K
R
R
S
R
T
E
F
A
L
K
Site 5
T34
P
R
K
R
R
S
R
T
E
F
A
L
K
E
I
Site 6
T58
I
P
Q
G
E
R
K
T
V
T
D
F
C
Y
L
Site 7
T60
Q
G
E
R
K
T
V
T
D
F
C
Y
L
L
D
Site 8
Y64
K
T
V
T
D
F
C
Y
L
L
D
K
S
K
Q
Site 9
Y82
G
L
R
D
L
P
Q
Y
G
Q
K
Q
W
Q
S
Site 10
Y90
G
Q
K
Q
W
Q
S
Y
F
G
R
T
F
D
V
Site 11
Y98
F
G
R
T
F
D
V
Y
T
K
L
W
K
F
Q
Site 12
Y116
R
Q
V
L
D
N
R
Y
G
L
K
R
W
Q
I
Site 13
Y134
A
S
K
I
G
Q
L
Y
Y
H
Y
Y
L
R
T
Site 14
Y135
S
K
I
G
Q
L
Y
Y
H
Y
Y
L
R
T
S
Site 15
Y137
I
G
Q
L
Y
Y
H
Y
Y
L
R
T
S
E
T
Site 16
Y138
G
Q
L
Y
Y
H
Y
Y
L
R
T
S
E
T
S
Site 17
S142
Y
H
Y
Y
L
R
T
S
E
T
S
Y
L
N
E
Site 18
S145
Y
L
R
T
S
E
T
S
Y
L
N
E
A
F
S
Site 19
Y146
L
R
T
S
E
T
S
Y
L
N
E
A
F
S
F
Site 20
S152
S
Y
L
N
E
A
F
S
F
Y
S
A
I
R
Q
Site 21
S161
Y
S
A
I
R
Q
R
S
Y
Y
S
Q
V
N
K
Site 22
Y162
S
A
I
R
Q
R
S
Y
Y
S
Q
V
N
K
E
Site 23
Y163
A
I
R
Q
R
S
Y
Y
S
Q
V
N
K
E
D
Site 24
S164
I
R
Q
R
S
Y
Y
S
Q
V
N
K
E
D
R
Site 25
Y181
L
V
V
K
K
L
R
Y
Y
A
R
F
I
V
V
Site 26
S206
K
D
L
V
K
E
L
S
D
E
I
E
D
Y
T
Site 27
Y212
L
S
D
E
I
E
D
Y
T
H
R
F
N
T
E
Site 28
T213
S
D
E
I
E
D
Y
T
H
R
F
N
T
E
D
Site 29
T248
M
V
L
N
D
D
N
T
I
V
I
T
S
N
R
Site 30
S253
D
N
T
I
V
I
T
S
N
R
L
A
E
T
G
Site 31
T259
T
S
N
R
L
A
E
T
G
A
P
L
L
E
Q
Site 32
S313
R
E
P
M
N
L
A
S
Q
M
N
K
P
G
M
Site 33
S323
N
K
P
G
M
Q
E
S
A
D
K
P
T
R
R
Site 34
T328
Q
E
S
A
D
K
P
T
R
R
E
N
P
H
K
Site 35
Y336
R
R
E
N
P
H
K
Y
L
L
Y
K
P
T
F
Site 36
Y339
N
P
H
K
Y
L
L
Y
K
P
T
F
S
Q
L
Site 37
T342
K
Y
L
L
Y
K
P
T
F
S
Q
L
Y
T
F
Site 38
T375
S
A
T
G
V
F
P
T
G
R
S
D
S
E
G
Site 39
S378
G
V
F
P
T
G
R
S
D
S
E
G
P
Y
D
Site 40
S380
F
P
T
G
R
S
D
S
E
G
P
Y
D
F
G
Site 41
Y384
R
S
D
S
E
G
P
Y
D
F
G
G
V
L
T
Site 42
S393
F
G
G
V
L
T
N
S
N
R
D
I
I
N
G
Site 43
Y422
C
L
H
P
G
D
L
Y
P
F
T
R
K
P
L
Site 44
Y461
C
L
L
S
P
T
A
Y
P
K
A
L
Q
D
Q
Site 45
S469
P
K
A
L
Q
D
Q
S
Q
R
G
S
L
F
T
Site 46
S473
Q
D
Q
S
Q
R
G
S
L
F
T
L
F
L
N
Site 47
T476
S
Q
R
G
S
L
F
T
L
F
L
N
N
P
L
Site 48
Y506
L
W
E
K
C
Q
E
Y
L
R
K
I
N
R
D
Site 49
T519
R
D
I
A
Q
L
L
T
H
S
R
S
I
D
Q
Site 50
S523
Q
L
L
T
H
S
R
S
I
D
Q
A
F
L
Q
Site 51
T560
M
H
K
I
F
R
E
T
R
N
Y
P
E
S
Y
Site 52
Y563
I
F
R
E
T
R
N
Y
P
E
S
Y
P
Q
L
Site 53
S566
E
T
R
N
Y
P
E
S
Y
P
Q
L
P
R
D
Site 54
T575
P
Q
L
P
R
D
E
T
V
E
N
P
H
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation