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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
JMY
Full Name:
Junction-mediating and -regulatory protein
Alias:
FLJ37870; Junction mediating and regulatory protein, p53 cofactor; Junction-mediating and regulatory protein
Type:
Transcription, coactivator/corepressor; Apoptosis
Mass (Da):
111445
Number AA:
988
UniProt ID:
Q8N9B5
International Prot ID:
IPI00182739
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003712
GO:0003713
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
L
E
E
T
L
E
S
D
W
V
A
V
R
P
Site 2
S56
R
T
A
Q
R
Q
R
S
G
S
R
E
Q
A
G
Site 3
S58
A
Q
R
Q
R
S
G
S
R
E
Q
A
G
A
R
Site 4
S75
A
E
A
G
G
A
A
S
D
G
S
R
G
P
G
Site 5
S78
G
G
A
A
S
D
G
S
R
G
P
G
S
P
A
Site 6
S83
D
G
S
R
G
P
G
S
P
A
G
R
G
R
P
Site 7
S95
G
R
P
E
A
T
A
S
A
T
L
V
R
S
P
Site 8
T97
P
E
A
T
A
S
A
T
L
V
R
S
P
G
P
Site 9
S101
A
S
A
T
L
V
R
S
P
G
P
R
R
S
S
Site 10
S107
R
S
P
G
P
R
R
S
S
A
W
A
E
G
G
Site 11
S108
S
P
G
P
R
R
S
S
A
W
A
E
G
G
S
Site 12
S115
S
A
W
A
E
G
G
S
P
R
S
T
R
S
L
Site 13
S118
A
E
G
G
S
P
R
S
T
R
S
L
L
G
D
Site 14
T119
E
G
G
S
P
R
S
T
R
S
L
L
G
D
P
Site 15
S121
G
S
P
R
S
T
R
S
L
L
G
D
P
R
L
Site 16
S130
L
G
D
P
R
L
R
S
P
G
S
K
G
A
E
Site 17
S133
P
R
L
R
S
P
G
S
K
G
A
E
S
R
L
Site 18
S138
P
G
S
K
G
A
E
S
R
L
R
S
P
V
R
Site 19
S142
G
A
E
S
R
L
R
S
P
V
R
A
K
P
I
Site 20
S155
P
I
P
G
Q
K
T
S
E
A
D
D
A
A
G
Site 21
S178
A
P
R
E
A
Q
V
S
S
V
R
I
V
S
A
Site 22
S179
P
R
E
A
Q
V
S
S
V
R
I
V
S
A
S
Site 23
S209
D
E
A
P
L
A
L
S
D
A
E
Q
P
P
P
Site 24
T218
A
E
Q
P
P
P
A
T
E
L
E
S
P
A
E
Site 25
S222
P
P
A
T
E
L
E
S
P
A
E
E
C
S
W
Site 26
S228
E
S
P
A
E
E
C
S
W
A
G
L
F
S
F
Site 27
S247
A
V
H
Q
Q
L
C
S
V
N
S
Q
L
E
P
Site 28
S250
Q
Q
L
C
S
V
N
S
Q
L
E
P
C
L
P
Site 29
T268
E
E
P
S
G
M
W
T
V
L
F
G
G
A
P
Site 30
T284
M
T
E
Q
E
I
D
T
L
C
Y
Q
L
Q
V
Site 31
T313
S
Q
V
L
F
T
E
T
D
D
P
E
E
Y
Y
Site 32
Y319
E
T
D
D
P
E
E
Y
Y
E
S
L
S
E
L
Site 33
Y320
T
D
D
P
E
E
Y
Y
E
S
L
S
E
L
R
Site 34
S322
D
P
E
E
Y
Y
E
S
L
S
E
L
R
Q
K
Site 35
S324
E
E
Y
Y
E
S
L
S
E
L
R
Q
K
G
Y
Site 36
Y331
S
E
L
R
Q
K
G
Y
E
E
V
L
Q
R
A
Site 37
Y362
M
V
E
L
L
D
L
Y
Q
M
E
D
E
A
Y
Site 38
Y369
Y
Q
M
E
D
E
A
Y
S
S
L
A
E
A
T
Site 39
S371
M
E
D
E
A
Y
S
S
L
A
E
A
T
T
E
Site 40
Y380
A
E
A
T
T
E
L
Y
Q
Y
L
L
Q
P
F
Site 41
Y382
A
T
T
E
L
Y
Q
Y
L
L
Q
P
F
R
D
Site 42
Y409
K
I
S
M
E
N
D
Y
L
G
P
R
R
I
E
Site 43
S417
L
G
P
R
R
I
E
S
L
Q
K
E
D
A
D
Site 44
Y455
A
K
A
Q
K
A
V
Y
D
R
M
R
A
D
Q
Site 45
Y482
E
R
M
E
K
L
Q
Y
A
V
S
K
E
T
L
Site 46
S485
E
K
L
Q
Y
A
V
S
K
E
T
L
Q
M
M
Site 47
S512
A
L
K
E
E
M
Q
S
L
R
G
G
T
E
A
Site 48
T517
M
Q
S
L
R
G
G
T
E
A
I
A
R
L
D
Site 49
Y530
L
D
Q
L
E
A
D
Y
Y
D
L
Q
L
Q
L
Site 50
Y531
D
Q
L
E
A
D
Y
Y
D
L
Q
L
Q
L
Y
Site 51
T553
K
C
E
E
L
L
L
T
A
Q
L
E
S
I
K
Site 52
S564
E
S
I
K
R
L
I
S
E
K
R
D
E
V
V
Site 53
Y572
E
K
R
D
E
V
V
Y
Y
D
T
Y
E
S
M
Site 54
Y573
K
R
D
E
V
V
Y
Y
D
T
Y
E
S
M
E
Site 55
T575
D
E
V
V
Y
Y
D
T
Y
E
S
M
E
A
M
Site 56
Y576
E
V
V
Y
Y
D
T
Y
E
S
M
E
A
M
L
Site 57
Y593
E
E
M
A
A
S
A
Y
L
Q
R
E
E
L
Q
Site 58
S617
E
A
R
R
G
R
V
S
A
K
K
S
Y
L
R
Site 59
S621
G
R
V
S
A
K
K
S
Y
L
R
N
K
K
E
Site 60
Y622
R
V
S
A
K
K
S
Y
L
R
N
K
K
E
I
Site 61
Y648
R
T
R
I
E
D
E
Y
R
T
H
H
T
V
Q
Site 62
S669
H
D
E
E
E
R
K
S
A
W
V
S
Q
E
R
Site 63
S673
E
R
K
S
A
W
V
S
Q
E
R
Q
R
T
L
Site 64
T679
V
S
Q
E
R
Q
R
T
L
D
R
L
R
T
F
Site 65
T685
R
T
L
D
R
L
R
T
F
K
Q
R
Y
P
G
Site 66
Y690
L
R
T
F
K
Q
R
Y
P
G
Q
V
I
L
K
Site 67
S698
P
G
Q
V
I
L
K
S
T
R
L
R
L
A
H
Site 68
S713
A
R
R
K
G
A
A
S
P
V
L
Q
E
D
H
Site 69
S723
L
Q
E
D
H
C
D
S
L
P
S
V
L
Q
V
Site 70
S747
G
R
V
K
R
G
P
S
Q
T
T
E
P
Q
S
Site 71
T749
V
K
R
G
P
S
Q
T
T
E
P
Q
S
L
V
Site 72
T750
K
R
G
P
S
Q
T
T
E
P
Q
S
L
V
Q
Site 73
S754
S
Q
T
T
E
P
Q
S
L
V
Q
L
E
D
T
Site 74
S785
S
E
L
P
P
T
I
S
L
P
L
L
N
N
N
Site 75
S797
N
N
N
L
E
P
C
S
V
T
I
N
P
L
P
Site 76
T799
N
L
E
P
C
S
V
T
I
N
P
L
P
S
P
Site 77
S805
V
T
I
N
P
L
P
S
P
L
P
P
T
P
P
Site 78
T810
L
P
S
P
L
P
P
T
P
P
P
P
P
P
P
Site 79
S832
P
L
P
V
A
K
D
S
G
P
E
T
L
E
K
Site 80
T836
A
K
D
S
G
P
E
T
L
E
K
D
L
P
R
Site 81
S854
N
E
K
R
I
P
K
S
A
S
A
P
S
A
H
Site 82
S856
K
R
I
P
K
S
A
S
A
P
S
A
H
L
F
Site 83
S859
P
K
S
A
S
A
P
S
A
H
L
F
D
S
S
Site 84
S865
P
S
A
H
L
F
D
S
S
Q
L
V
S
A
R
Site 85
S866
S
A
H
L
F
D
S
S
Q
L
V
S
A
R
K
Site 86
S870
F
D
S
S
Q
L
V
S
A
R
K
K
L
R
K
Site 87
T878
A
R
K
K
L
R
K
T
A
E
G
L
Q
R
R
Site 88
S888
G
L
Q
R
R
R
V
S
S
P
M
D
E
V
L
Site 89
S889
L
Q
R
R
R
V
S
S
P
M
D
E
V
L
A
Site 90
S897
P
M
D
E
V
L
A
S
L
K
R
G
S
F
H
Site 91
S902
L
A
S
L
K
R
G
S
F
H
L
K
K
V
E
Site 92
T912
L
K
K
V
E
Q
R
T
L
P
P
F
P
D
E
Site 93
S922
P
F
P
D
E
D
D
S
N
N
I
L
A
Q
I
Site 94
S946
Q
K
D
V
L
R
E
S
F
T
L
L
P
D
T
Site 95
T948
D
V
L
R
E
S
F
T
L
L
P
D
T
D
P
Site 96
T953
S
F
T
L
L
P
D
T
D
P
L
T
R
S
I
Site 97
T957
L
P
D
T
D
P
L
T
R
S
I
H
E
A
L
Site 98
S959
D
T
D
P
L
T
R
S
I
H
E
A
L
R
R
Site 99
S971
L
R
R
I
K
E
A
S
P
E
S
E
D
E
E
Site 100
S974
I
K
E
A
S
P
E
S
E
D
E
E
E
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation