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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABTB2
Full Name:
Ankyrin repeat and BTB/POZ domain-containing protein 2
Alias:
Type:
Mass (Da):
93290
Number AA:
839
UniProt ID:
Q8N961
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
D
G
L
R
R
G
K
S
A
R
C
G
L
T
F
Site 2
S63
I
R
A
R
V
M
A
S
H
S
P
D
G
G
G
Site 3
S65
A
R
V
M
A
S
H
S
P
D
G
G
G
A
G
Site 4
S112
K
N
A
N
G
V
L
S
L
P
A
Y
F
S
P
Site 5
Y120
L
P
A
Y
F
S
P
Y
N
G
G
S
L
G
H
Site 6
Y134
H
D
E
R
A
D
A
Y
A
Q
L
E
L
R
T
Site 7
T141
Y
A
Q
L
E
L
R
T
L
E
Q
S
L
L
A
Site 8
S162
S
E
L
S
D
L
V
S
R
A
M
H
H
M
Q
Site 9
S179
H
P
L
C
P
G
A
S
P
A
R
Q
A
R
Q
Site 10
T192
R
Q
P
P
Q
P
I
T
W
S
P
D
A
L
H
Site 11
S194
P
P
Q
P
I
T
W
S
P
D
A
L
H
T
L
Site 12
T200
W
S
P
D
A
L
H
T
L
Y
Y
F
L
R
C
Site 13
Y202
P
D
A
L
H
T
L
Y
Y
F
L
R
C
P
Q
Site 14
S212
L
R
C
P
Q
M
E
S
M
E
N
P
N
L
D
Site 15
T224
N
L
D
P
P
R
M
T
L
N
N
E
R
P
F
Site 16
Y247
W
M
R
V
A
I
T
Y
A
E
H
R
R
S
L
Site 17
S253
T
Y
A
E
H
R
R
S
L
T
V
D
S
G
D
Site 18
T255
A
E
H
R
R
S
L
T
V
D
S
G
D
I
R
Site 19
S286
L
K
P
E
H
C
F
S
S
F
R
R
L
D
A
Site 20
S287
K
P
E
H
C
F
S
S
F
R
R
L
D
A
R
Site 21
T297
R
L
D
A
R
A
A
T
E
K
F
N
Q
D
L
Site 22
T331
L
G
P
D
G
V
N
T
M
D
D
Q
G
M
T
Site 23
S368
N
L
D
I
Q
V
P
S
N
S
P
R
H
P
S
Site 24
S370
D
I
Q
V
P
S
N
S
P
R
H
P
S
I
H
Site 25
S375
S
N
S
P
R
H
P
S
I
H
P
D
S
R
H
Site 26
S380
H
P
S
I
H
P
D
S
R
H
W
T
S
L
T
Site 27
T384
H
P
D
S
R
H
W
T
S
L
T
F
A
V
L
Site 28
S385
P
D
S
R
H
W
T
S
L
T
F
A
V
L
H
Site 29
T387
S
R
H
W
T
S
L
T
F
A
V
L
H
G
H
Site 30
S411
A
G
A
H
V
E
G
S
A
V
N
G
G
E
D
Site 31
S419
A
V
N
G
G
E
D
S
Y
A
E
T
P
L
Q
Site 32
Y420
V
N
G
G
E
D
S
Y
A
E
T
P
L
Q
L
Site 33
T423
G
E
D
S
Y
A
E
T
P
L
Q
L
A
S
A
Site 34
S450
R
G
A
D
P
L
L
S
M
L
E
A
H
G
M
Site 35
S508
L
A
E
G
V
E
E
S
D
A
S
S
Q
G
S
Site 36
S511
G
V
E
E
S
D
A
S
S
Q
G
S
G
S
E
Site 37
S512
V
E
E
S
D
A
S
S
Q
G
S
G
S
E
G
Site 38
S515
S
D
A
S
S
Q
G
S
G
S
E
G
P
V
R
Site 39
S517
A
S
S
Q
G
S
G
S
E
G
P
V
R
L
S
Site 40
S524
S
E
G
P
V
R
L
S
R
T
R
T
K
A
L
Site 41
T528
V
R
L
S
R
T
R
T
K
A
L
Q
E
A
M
Site 42
Y536
K
A
L
Q
E
A
M
Y
Y
S
A
E
H
G
Y
Site 43
Y537
A
L
Q
E
A
M
Y
Y
S
A
E
H
G
Y
V
Site 44
Y543
Y
Y
S
A
E
H
G
Y
V
D
I
T
M
E
L
Site 45
T547
E
H
G
Y
V
D
I
T
M
E
L
R
A
L
G
Site 46
S565
K
L
H
I
W
I
E
S
L
R
T
S
F
S
Q
Site 47
T568
I
W
I
E
S
L
R
T
S
F
S
Q
S
R
Y
Site 48
S569
W
I
E
S
L
R
T
S
F
S
Q
S
R
Y
S
Site 49
S571
E
S
L
R
T
S
F
S
Q
S
R
Y
S
V
V
Site 50
S573
L
R
T
S
F
S
Q
S
R
Y
S
V
V
Q
S
Site 51
Y575
T
S
F
S
Q
S
R
Y
S
V
V
Q
S
L
L
Site 52
S576
S
F
S
Q
S
R
Y
S
V
V
Q
S
L
L
R
Site 53
S580
S
R
Y
S
V
V
Q
S
L
L
R
D
F
S
S
Site 54
S586
Q
S
L
L
R
D
F
S
S
I
R
E
E
E
Y
Site 55
S587
S
L
L
R
D
F
S
S
I
R
E
E
E
Y
N
Site 56
T599
E
Y
N
E
E
L
V
T
E
G
L
Q
L
M
F
Site 57
S612
M
F
D
I
L
K
T
S
K
N
D
S
V
I
Q
Site 58
S616
L
K
T
S
K
N
D
S
V
I
Q
Q
L
A
T
Site 59
T626
Q
Q
L
A
T
I
F
T
H
C
Y
G
S
S
P
Site 60
S632
F
T
H
C
Y
G
S
S
P
I
P
S
I
P
E
Site 61
S636
Y
G
S
S
P
I
P
S
I
P
E
I
R
K
T
Site 62
T643
S
I
P
E
I
R
K
T
L
P
A
R
L
D
P
Site 63
S659
F
L
N
N
K
E
M
S
D
V
T
F
L
V
E
Site 64
T662
N
K
E
M
S
D
V
T
F
L
V
E
G
K
L
Site 65
T686
T
A
S
N
R
F
K
T
L
M
T
N
K
S
E
Site 66
S692
K
T
L
M
T
N
K
S
E
Q
D
G
D
S
S
Site 67
S698
K
S
E
Q
D
G
D
S
S
K
T
I
E
I
S
Site 68
S699
S
E
Q
D
G
D
S
S
K
T
I
E
I
S
D
Site 69
T701
Q
D
G
D
S
S
K
T
I
E
I
S
D
M
K
Site 70
S726
L
Y
Y
G
G
T
E
S
M
E
I
P
T
T
D
Site 71
S758
R
H
C
E
I
L
C
S
Q
T
L
S
M
E
S
Site 72
T769
S
M
E
S
A
V
N
T
Y
K
Y
A
K
I
H
Site 73
Y772
S
A
V
N
T
Y
K
Y
A
K
I
H
N
A
P
Site 74
Y807
D
A
F
R
Q
L
I
Y
G
R
S
S
K
V
Q
Site 75
S810
R
Q
L
I
Y
G
R
S
S
K
V
Q
G
L
D
Site 76
S811
Q
L
I
Y
G
R
S
S
K
V
Q
G
L
D
P
Site 77
T825
P
L
Q
D
L
Q
N
T
L
A
E
R
V
H
S
Site 78
Y834
A
E
R
V
H
S
V
Y
I
T
S
R
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation