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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX51
Full Name:
ATP-dependent RNA helicase DDX51
Alias:
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51; DEAD box protein 51
Type:
EC 3.6.1.-; Hydrolase
Mass (Da):
72457
Number AA:
666
UniProt ID:
Q8N8A6
International Prot ID:
IPI00217541
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008026
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S40
A
L
L
E
R
L
Q
S
R
A
R
E
R
Q
Q
Site 2
T54
Q
Q
R
E
P
A
Q
T
E
A
A
A
S
T
E
Site 3
S59
A
Q
T
E
A
A
A
S
T
E
P
A
T
R
R
Site 4
T64
A
A
S
T
E
P
A
T
R
R
R
R
R
P
R
Site 5
S83
V
N
D
A
E
P
G
S
P
E
A
P
Q
G
K
Site 6
S103
G
E
D
A
G
A
E
S
N
E
E
A
P
G
E
Site 7
S112
E
E
A
P
G
E
P
S
A
G
S
S
E
E
A
Site 8
S115
P
G
E
P
S
A
G
S
S
E
E
A
P
G
E
Site 9
S116
G
E
P
S
A
G
S
S
E
E
A
P
G
E
P
Site 10
S128
G
E
P
S
A
G
S
S
E
E
A
P
G
E
R
Site 11
S136
E
E
A
P
G
E
R
S
T
S
A
S
A
E
A
Site 12
T137
E
A
P
G
E
R
S
T
S
A
S
A
E
A
A
Site 13
S138
A
P
G
E
R
S
T
S
A
S
A
E
A
A
P
Site 14
S140
G
E
R
S
T
S
A
S
A
E
A
A
P
D
G
Site 15
T193
N
C
V
R
R
N
V
T
E
D
L
V
P
I
E
Site 16
S219
Q
L
R
A
H
G
I
S
S
Y
F
P
V
Q
A
Site 17
S250
G
R
G
G
Y
R
P
S
D
L
C
V
S
A
P
Site 18
S255
R
P
S
D
L
C
V
S
A
P
T
G
S
G
K
Site 19
Y304
V
S
K
V
F
N
I
Y
T
D
A
T
P
L
R
Site 20
T305
S
K
V
F
N
I
Y
T
D
A
T
P
L
R
V
Site 21
S313
D
A
T
P
L
R
V
S
L
V
T
G
Q
K
S
Site 22
T316
P
L
R
V
S
L
V
T
G
Q
K
S
L
A
K
Site 23
S320
S
L
V
T
G
Q
K
S
L
A
K
E
Q
E
S
Site 24
S327
S
L
A
K
E
Q
E
S
L
V
Q
K
T
A
D
Site 25
T357
L
V
D
H
I
D
Q
T
P
G
F
S
L
Q
Q
Site 26
T433
Q
K
L
L
F
S
A
T
L
T
Q
N
P
E
K
Site 27
T435
L
L
F
S
A
T
L
T
Q
N
P
E
K
L
Q
Site 28
S453
L
H
Q
P
R
L
F
S
T
G
L
A
H
R
G
Site 29
T464
A
H
R
G
L
E
D
T
D
G
D
G
D
S
G
Site 30
S470
D
T
D
G
D
G
D
S
G
K
Y
A
F
P
V
Site 31
Y473
G
D
G
D
S
G
K
Y
A
F
P
V
G
L
T
Site 32
S487
T
H
H
Y
V
P
C
S
L
S
S
K
P
L
V
Site 33
T511
F
S
R
V
L
C
F
T
N
S
R
E
N
S
H
Site 34
S513
R
V
L
C
F
T
N
S
R
E
N
S
H
R
L
Site 35
S517
F
T
N
S
R
E
N
S
H
R
L
F
L
L
V
Site 36
S536
G
V
D
V
A
E
F
S
S
R
Y
G
P
G
Q
Site 37
T562
K
I
Q
L
L
I
S
T
D
A
T
A
R
G
I
Site 38
Y580
G
V
E
L
V
V
N
Y
D
A
P
Q
Y
L
R
Site 39
Y585
V
N
Y
D
A
P
Q
Y
L
R
T
Y
V
H
R
Site 40
Y589
A
P
Q
Y
L
R
T
Y
V
H
R
V
G
R
T
Site 41
T622
R
R
F
L
R
M
L
T
E
A
G
A
P
E
L
Site 42
S635
E
L
Q
R
H
E
L
S
S
K
L
L
Q
P
L
Site 43
S636
L
Q
R
H
E
L
S
S
K
L
L
Q
P
L
V
Site 44
Y646
L
Q
P
L
V
P
R
Y
E
E
A
L
S
Q
L
Site 45
S651
P
R
Y
E
E
A
L
S
Q
L
E
E
S
V
K
Site 46
S656
A
L
S
Q
L
E
E
S
V
K
E
E
R
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation