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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLD5
Full Name:
Inactive phospholipase D5
Alias:
Inactive choline phosphatase 5;Inactive phosphatidylcholine-hydrolyzing phospholipase D5;PLDc
Type:
Mass (Da):
61312
Number AA:
536
UniProt ID:
Q8N7P1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
I
R
Q
H
E
W
L
S
A
S
P
H
E
G
F
Site 2
S12
Q
H
E
W
L
S
A
S
P
H
E
G
F
E
Q
Site 3
S24
F
E
Q
M
R
L
K
S
R
P
K
E
P
S
P
Site 4
S30
K
S
R
P
K
E
P
S
P
S
L
T
R
V
G
Site 5
S32
R
P
K
E
P
S
P
S
L
T
R
V
G
A
N
Site 6
T34
K
E
P
S
P
S
L
T
R
V
G
A
N
F
Y
Site 7
S42
R
V
G
A
N
F
Y
S
S
V
K
Q
Q
D
Y
Site 8
S43
V
G
A
N
F
Y
S
S
V
K
Q
Q
D
Y
S
Site 9
Y49
S
S
V
K
Q
Q
D
Y
S
A
S
V
W
L
R
Site 10
S50
S
V
K
Q
Q
D
Y
S
A
S
V
W
L
R
R
Site 11
S52
K
Q
Q
D
Y
S
A
S
V
W
L
R
R
K
D
Site 12
S64
R
K
D
K
L
E
H
S
Q
Q
K
C
I
V
I
Site 13
S100
G
E
D
E
D
G
L
S
E
K
N
C
Q
N
K
Site 14
Y122
N
I
P
E
G
L
N
Y
S
E
N
A
P
F
H
Site 15
S123
I
P
E
G
L
N
Y
S
E
N
A
P
F
H
L
Site 16
S151
K
K
S
V
D
I
V
S
S
H
W
D
L
N
H
Site 17
S178
E
K
L
L
Q
L
T
S
Q
N
I
E
I
K
L
Site 18
Y208
L
K
G
A
E
V
T
Y
M
N
M
T
A
Y
N
Site 19
Y214
T
Y
M
N
M
T
A
Y
N
K
G
R
L
Q
S
Site 20
S221
Y
N
K
G
R
L
Q
S
S
F
W
I
V
D
K
Site 21
S222
N
K
G
R
L
Q
S
S
F
W
I
V
D
K
Q
Site 22
S242
S
A
G
L
D
W
Q
S
L
G
Q
M
K
E
L
Site 23
S271
Q
R
I
F
A
L
Y
S
S
L
K
F
K
S
R
Site 24
S277
Y
S
S
L
K
F
K
S
R
V
P
Q
T
W
S
Site 25
T282
F
K
S
R
V
P
Q
T
W
S
K
R
L
Y
G
Site 26
S284
S
R
V
P
Q
T
W
S
K
R
L
Y
G
V
Y
Site 27
Y288
Q
T
W
S
K
R
L
Y
G
V
Y
D
N
E
K
Site 28
Y291
S
K
R
L
Y
G
V
Y
D
N
E
K
K
L
Q
Site 29
S306
L
Q
L
N
E
T
K
S
Q
A
F
V
S
N
S
Site 30
S311
T
K
S
Q
A
F
V
S
N
S
P
K
L
F
C
Site 31
S313
S
Q
A
F
V
S
N
S
P
K
L
F
C
P
K
Site 32
Y341
D
D
A
K
Q
Y
V
Y
I
A
V
M
D
Y
L
Site 33
S351
V
M
D
Y
L
P
I
S
S
T
S
T
K
R
T
Site 34
T353
D
Y
L
P
I
S
S
T
S
T
K
R
T
Y
W
Site 35
T355
L
P
I
S
S
T
S
T
K
R
T
Y
W
P
D
Site 36
T358
S
S
T
S
T
K
R
T
Y
W
P
D
L
D
A
Site 37
Y359
S
T
S
T
K
R
T
Y
W
P
D
L
D
A
K
Site 38
S383
V
R
V
R
L
L
L
S
F
W
K
E
T
D
P
Site 39
T392
W
K
E
T
D
P
L
T
F
N
F
I
S
S
L
Site 40
T433
T
K
E
Q
K
N
H
T
F
P
R
L
N
R
N
Site 41
Y442
P
R
L
N
R
N
K
Y
M
V
T
D
G
A
A
Site 42
Y495
D
V
F
E
R
D
W
Y
S
P
Y
A
K
T
L
Site 43
S496
V
F
E
R
D
W
Y
S
P
Y
A
K
T
L
Q
Site 44
T501
W
Y
S
P
Y
A
K
T
L
Q
P
T
K
Q
P
Site 45
S512
T
K
Q
P
N
C
S
S
L
F
K
L
K
P
L
Site 46
S520
L
F
K
L
K
P
L
S
N
K
T
A
T
D
D
Site 47
T528
N
K
T
A
T
D
D
T
G
G
K
D
P
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation