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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF283
Full Name:
Zinc finger protein 283
Alias:
Hzf41; Zinc finger protein 19; Zn283; Znf283
Type:
Intracellular, Nucleus protein
Mass (Da):
77988
Number AA:
679
UniProt ID:
Q8N7M2
International Prot ID:
IPI00167241
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
V
Q
W
C
D
L
G
S
L
Q
A
P
P
P
G
Site 2
Y40
S
L
L
S
S
W
D
Y
S
S
G
F
S
G
F
Site 3
S42
L
S
S
W
D
Y
S
S
G
F
S
G
F
C
A
Site 4
S50
G
F
S
G
F
C
A
S
P
I
E
E
S
H
G
Site 5
S61
E
S
H
G
A
L
I
S
S
C
N
S
R
T
M
Site 6
S62
S
H
G
A
L
I
S
S
C
N
S
R
T
M
T
Site 7
S65
A
L
I
S
S
C
N
S
R
T
M
T
D
G
L
Site 8
T69
S
C
N
S
R
T
M
T
D
G
L
V
T
F
R
Site 9
S83
R
D
V
A
I
D
F
S
Q
E
E
W
E
C
L
Site 10
Y98
D
P
A
Q
R
D
L
Y
V
D
V
M
L
E
N
Site 11
S111
E
N
Y
S
N
L
V
S
L
D
L
E
S
K
T
Site 12
S116
L
V
S
L
D
L
E
S
K
T
Y
E
T
K
K
Site 13
T118
S
L
D
L
E
S
K
T
Y
E
T
K
K
I
F
Site 14
Y119
L
D
L
E
S
K
T
Y
E
T
K
K
I
F
S
Site 15
S144
Q
W
E
M
K
D
K
S
K
T
L
G
L
E
A
Site 16
T146
E
M
K
D
K
S
K
T
L
G
L
E
A
S
I
Site 17
S152
K
T
L
G
L
E
A
S
I
F
R
N
N
W
K
Site 18
Y174
L
K
G
H
Q
E
G
Y
F
S
Q
M
I
I
S
Site 19
Y182
F
S
Q
M
I
I
S
Y
E
K
I
P
S
Y
R
Site 20
S187
I
S
Y
E
K
I
P
S
Y
R
K
S
K
S
L
Site 21
Y188
S
Y
E
K
I
P
S
Y
R
K
S
K
S
L
T
Site 22
S191
K
I
P
S
Y
R
K
S
K
S
L
T
P
H
Q
Site 23
S193
P
S
Y
R
K
S
K
S
L
T
P
H
Q
R
I
Site 24
T195
Y
R
K
S
K
S
L
T
P
H
Q
R
I
H
N
Site 25
Y207
I
H
N
T
E
K
S
Y
V
C
K
E
C
G
K
Site 26
S217
K
E
C
G
K
A
C
S
H
G
S
K
L
V
Q
Site 27
S220
G
K
A
C
S
H
G
S
K
L
V
Q
H
E
R
Site 28
T230
V
Q
H
E
R
T
H
T
A
E
K
H
F
E
C
Site 29
Y244
C
K
E
C
G
K
N
Y
L
S
A
Y
Q
L
N
Site 30
Y248
G
K
N
Y
L
S
A
Y
Q
L
N
V
H
Q
R
Site 31
T258
N
V
H
Q
R
F
H
T
G
E
K
P
Y
E
C
Site 32
Y263
F
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 33
T271
E
C
K
E
C
G
K
T
F
S
W
G
S
S
L
Site 34
S273
K
E
C
G
K
T
F
S
W
G
S
S
L
V
K
Site 35
S276
G
K
T
F
S
W
G
S
S
L
V
K
H
E
R
Site 36
S277
K
T
F
S
W
G
S
S
L
V
K
H
E
R
I
Site 37
T286
V
K
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 38
Y291
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 39
S301
K
E
C
G
K
A
F
S
R
G
Y
H
L
T
Q
Site 40
Y304
G
K
A
F
S
R
G
Y
H
L
T
Q
H
Q
K
Site 41
Y319
I
H
I
G
V
K
S
Y
K
C
K
E
C
G
K
Site 42
S332
G
K
A
F
F
W
G
S
S
L
A
K
H
E
I
Site 43
T342
A
K
H
E
I
I
H
T
G
E
K
P
Y
K
C
Site 44
Y347
I
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 45
Y360
G
K
A
F
S
R
G
Y
Q
L
T
Q
H
Q
K
Site 46
Y375
I
H
T
G
K
K
P
Y
E
C
K
I
C
G
K
Site 47
S416
G
K
A
F
N
C
G
S
S
L
I
Q
H
E
R
Site 48
T426
I
Q
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 49
S441
K
E
C
G
K
A
F
S
R
G
Y
H
L
S
Q
Site 50
Y444
G
K
A
F
S
R
G
Y
H
L
S
Q
H
Q
K
Site 51
S469
K
E
C
G
K
A
F
S
W
G
S
S
L
V
K
Site 52
S472
G
K
A
F
S
W
G
S
S
L
V
K
H
E
R
Site 53
S473
K
A
F
S
W
G
S
S
L
V
K
H
E
R
V
Site 54
T482
V
K
H
E
R
V
H
T
G
E
K
S
H
E
C
Site 55
T495
E
C
K
E
C
G
K
T
F
C
S
G
Y
Q
L
Site 56
S528
G
K
A
F
N
C
G
S
S
L
V
Q
H
E
R
Site 57
T538
V
Q
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 58
T566
T
Q
H
Q
K
I
H
T
G
E
K
P
F
K
C
Site 59
T594
V
K
H
E
R
V
H
T
N
E
K
S
Y
E
C
Site 60
Y599
V
H
T
N
E
K
S
Y
E
C
K
D
C
G
K
Site 61
T622
S
V
H
Q
R
F
H
T
G
E
K
L
Y
Q
R
Site 62
Y627
F
H
T
G
E
K
L
Y
Q
R
K
E
F
G
K
Site 63
T635
Q
R
K
E
F
G
K
T
F
T
H
G
S
K
L
Site 64
S640
G
K
T
F
T
H
G
S
K
L
V
H
E
R
T
Site 65
T647
S
K
L
V
H
E
R
T
H
S
N
D
K
P
Y
Site 66
S649
L
V
H
E
R
T
H
S
N
D
K
P
Y
K
Y
Site 67
Y654
T
H
S
N
D
K
P
Y
K
Y
N
E
C
G
E
Site 68
Y656
S
N
D
K
P
Y
K
Y
N
E
C
G
E
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation