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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC17
Full Name:
Leucine-rich repeat-containing protein 17
Alias:
37 kDa leucine-rich repeat (LRR) protein; H_RG318M05.3; Leucine rich repeat containing 17; LRC17; P37NB
Type:
Unknown function
Mass (Da):
51800
Number AA:
441
UniProt ID:
Q8N6Y2
International Prot ID:
IPI00171160
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0048539
GO:0045671
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
A
A
E
L
R
K
A
S
P
G
S
V
R
S
R
Site 2
S25
L
R
K
A
S
P
G
S
V
R
S
R
V
N
H
Site 3
S28
A
S
P
G
S
V
R
S
R
V
N
H
G
R
A
Site 4
S42
A
G
G
G
R
R
G
S
N
P
V
K
R
Y
A
Site 5
Y48
G
S
N
P
V
K
R
Y
A
P
G
L
P
C
D
Site 6
Y57
P
G
L
P
C
D
V
Y
T
Y
L
H
E
K
Y
Site 7
T58
G
L
P
C
D
V
Y
T
Y
L
H
E
K
Y
L
Site 8
Y59
L
P
C
D
V
Y
T
Y
L
H
E
K
Y
L
D
Site 9
Y64
Y
T
Y
L
H
E
K
Y
L
D
C
Q
E
R
K
Site 10
Y74
C
Q
E
R
K
L
V
Y
V
L
P
G
W
P
Q
Site 11
T95
L
A
R
N
K
I
R
T
L
K
N
N
M
F
S
Site 12
S109
S
K
F
K
K
L
K
S
L
D
L
Q
Q
N
E
Site 13
S118
D
L
Q
Q
N
E
I
S
K
I
E
S
E
A
F
Site 14
S122
N
E
I
S
K
I
E
S
E
A
F
F
G
L
N
Site 15
T133
F
G
L
N
K
L
T
T
L
L
L
Q
H
N
Q
Site 16
T145
H
N
Q
I
K
V
L
T
E
E
V
F
I
Y
T
Site 17
Y157
I
Y
T
P
L
L
S
Y
L
R
L
Y
D
N
P
Site 18
Y161
L
L
S
Y
L
R
L
Y
D
N
P
W
H
C
T
Site 19
Y189
R
N
R
N
L
G
N
Y
A
K
C
E
S
P
Q
Site 20
S194
G
N
Y
A
K
C
E
S
P
Q
E
Q
K
N
K
Site 21
S208
K
K
L
R
Q
I
K
S
E
Q
L
C
N
E
E
Site 22
S227
L
D
P
K
P
Q
V
S
G
R
P
P
V
I
K
Site 23
S276
D
I
V
K
L
D
L
S
Y
N
K
I
N
Q
L
Site 24
Y277
I
V
K
L
D
L
S
Y
N
K
I
N
Q
L
R
Site 25
S301
L
K
K
L
N
L
S
S
N
G
I
E
F
I
D
Site 26
S324
H
L
E
E
L
D
L
S
N
N
S
L
Q
N
F
Site 27
S327
E
L
D
L
S
N
N
S
L
Q
N
F
D
Y
G
Site 28
Y333
N
S
L
Q
N
F
D
Y
G
V
L
E
D
L
Y
Site 29
T380
F
N
G
L
E
C
K
T
P
E
E
Y
K
G
W
Site 30
Y384
E
C
K
T
P
E
E
Y
K
G
W
S
V
G
K
Site 31
Y392
K
G
W
S
V
G
K
Y
I
R
S
Y
Y
E
E
Site 32
S395
S
V
G
K
Y
I
R
S
Y
Y
E
E
C
P
K
Site 33
Y396
V
G
K
Y
I
R
S
Y
Y
E
E
C
P
K
D
Site 34
Y397
G
K
Y
I
R
S
Y
Y
E
E
C
P
K
D
K
Site 35
Y408
P
K
D
K
L
P
A
Y
P
E
S
F
D
Q
D
Site 36
S411
K
L
P
A
Y
P
E
S
F
D
Q
D
T
E
D
Site 37
T416
P
E
S
F
D
Q
D
T
E
D
D
E
W
E
K
Site 38
T429
E
K
K
H
R
D
H
T
A
K
K
Q
S
V
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation