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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
USHBP1
Full Name:
Usher syndrome type-1C protein-binding protein 1
Alias:
AIE-75-binding protein;MCC-2
Type:
Mass (Da):
76068
Number AA:
703
UniProt ID:
Q8N6Y0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
S
A
R
A
T
R
P
R
S
R
R
G
Site 2
S10
A
R
A
T
R
P
R
S
R
R
G
R
H
A
P
Site 3
S28
L
D
P
V
A
E
S
S
E
E
V
E
A
A
S
Site 4
S35
S
E
E
V
E
A
A
S
G
S
S
K
P
S
F
Site 5
S37
E
V
E
A
A
S
G
S
S
K
P
S
F
A
P
Site 6
S41
A
S
G
S
S
K
P
S
F
A
P
P
P
V
S
Site 7
S48
S
F
A
P
P
P
V
S
S
G
L
E
Q
L
G
Site 8
S61
L
G
P
M
E
E
V
S
G
Q
G
L
G
S
R
Site 9
S77
D
K
K
M
D
G
G
S
G
R
E
L
A
S
A
Site 10
S83
G
S
G
R
E
L
A
S
A
P
E
V
P
H
K
Site 11
T108
A
A
L
Q
Y
K
E
T
V
P
P
G
N
G
A
Site 12
T121
G
A
P
D
V
F
Q
T
L
Q
H
T
L
S
S
Site 13
S127
Q
T
L
Q
H
T
L
S
S
L
E
A
A
A
A
Site 14
S142
A
W
R
H
Q
P
P
S
H
S
G
P
M
E
F
Site 15
S144
R
H
Q
P
P
S
H
S
G
P
M
E
F
E
G
Site 16
T152
G
P
M
E
F
E
G
T
S
E
G
G
A
G
S
Site 17
S153
P
M
E
F
E
G
T
S
E
G
G
A
G
S
L
Site 18
S159
T
S
E
G
G
A
G
S
L
G
K
Q
E
G
A
Site 19
S168
G
K
Q
E
G
A
G
S
C
Q
R
E
A
A
R
Site 20
S188
A
W
L
R
L
A
L
S
S
R
E
D
E
L
V
Site 21
S189
W
L
R
L
A
L
S
S
R
E
D
E
L
V
R
Site 22
T197
R
E
D
E
L
V
R
T
Q
A
S
L
E
A
I
Site 23
S200
E
L
V
R
T
Q
A
S
L
E
A
I
R
A
E
Site 24
T210
A
I
R
A
E
K
E
T
L
Q
K
E
V
Q
E
Site 25
S221
E
V
Q
E
L
Q
D
S
L
L
R
L
E
P
C
Site 26
S232
L
E
P
C
P
H
L
S
H
N
Q
A
G
G
S
Site 27
S239
S
H
N
Q
A
G
G
S
G
S
G
S
S
S
S
Site 28
S241
N
Q
A
G
G
S
G
S
G
S
S
S
S
E
A
Site 29
S243
A
G
G
S
G
S
G
S
S
S
S
E
A
D
R
Site 30
S245
G
S
G
S
G
S
S
S
S
E
A
D
R
E
P
Site 31
S246
S
G
S
G
S
S
S
S
E
A
D
R
E
P
W
Site 32
T255
A
D
R
E
P
W
E
T
Q
D
S
F
S
L
A
Site 33
S258
E
P
W
E
T
Q
D
S
F
S
L
A
H
P
L
Site 34
S260
W
E
T
Q
D
S
F
S
L
A
H
P
L
L
R
Site 35
S271
P
L
L
R
R
L
R
S
H
S
S
T
Q
I
L
Site 36
S273
L
R
R
L
R
S
H
S
S
T
Q
I
L
G
S
Site 37
S274
R
R
L
R
S
H
S
S
T
Q
I
L
G
S
L
Site 38
T275
R
L
R
S
H
S
S
T
Q
I
L
G
S
L
P
Site 39
S280
S
S
T
Q
I
L
G
S
L
P
N
Q
P
L
S
Site 40
S287
S
L
P
N
Q
P
L
S
P
E
M
H
I
M
E
Site 41
S303
Q
M
E
Q
L
R
G
S
I
E
K
L
K
C
F
Site 42
S315
K
C
F
N
R
L
L
S
A
V
L
Q
G
Y
K
Site 43
S329
K
G
R
C
E
G
L
S
M
Q
L
G
Q
R
E
Site 44
T340
G
Q
R
E
A
E
A
T
A
L
H
L
A
L
Q
Site 45
S349
L
H
L
A
L
Q
Y
S
E
H
C
E
E
A
Y
Site 46
S367
L
A
L
R
E
A
D
S
G
A
G
D
E
A
P
Site 47
S376
A
G
D
E
A
P
M
S
D
L
Q
A
A
E
K
Site 48
S407
A
Q
Q
N
P
Q
P
S
P
E
G
S
S
V
D
Site 49
S411
P
Q
P
S
P
E
G
S
S
V
D
K
P
T
P
Site 50
S412
Q
P
S
P
E
G
S
S
V
D
K
P
T
P
Q
Site 51
T417
G
S
S
V
D
K
P
T
P
Q
E
V
A
F
Q
Site 52
Y428
V
A
F
Q
L
R
S
Y
V
Q
R
L
Q
E
R
Site 53
S437
Q
R
L
Q
E
R
R
S
L
M
K
I
L
S
E
Site 54
S443
R
S
L
M
K
I
L
S
E
P
G
P
T
L
A
Site 55
S545
L
Q
A
G
G
A
N
S
S
G
G
H
S
S
G
Site 56
S546
Q
A
G
G
A
N
S
S
G
G
H
S
S
G
G
Site 57
S550
A
N
S
S
G
G
H
S
S
G
G
G
S
S
G
Site 58
S551
N
S
S
G
G
H
S
S
G
G
G
S
S
G
D
Site 59
S555
G
H
S
S
G
G
G
S
S
G
D
E
E
E
W
Site 60
S556
H
S
S
G
G
G
S
S
G
D
E
E
E
W
Y
Site 61
Y563
S
G
D
E
E
E
W
Y
Q
G
L
P
A
V
P
Site 62
S574
P
A
V
P
G
G
T
S
G
I
D
G
G
Q
V
Site 63
S610
D
L
Q
E
Q
L
Q
S
L
R
R
E
L
E
Q
Site 64
S627
Q
K
G
R
A
R
R
S
Q
S
A
E
L
N
R
Site 65
S629
G
R
A
R
R
S
Q
S
A
E
L
N
R
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation