KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
IL22RA1
Full Name:
Interleukin-22 receptor subunit alpha-1
Alias:
Cytokine receptor class-II member 9;Cytokine receptor family 2 member 9;ZcytoR11
Type:
Mass (Da):
63077
Number AA:
574
UniProt ID:
Q8N6P7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
R
T
L
L
T
I
L
T
V
Site 2
Y186
L
G
G
K
Q
R
E
Y
E
F
F
G
L
T
P
Site 3
Y215
W
A
K
E
S
A
P
Y
M
C
R
V
K
T
L
Site 4
S230
P
D
R
T
W
T
Y
S
F
S
G
A
F
L
F
Site 5
Y251
A
V
L
C
Y
L
S
Y
R
Y
V
T
K
P
P
Site 6
Y253
L
C
Y
L
S
Y
R
Y
V
T
K
P
P
A
P
Site 7
T255
Y
L
S
Y
R
Y
V
T
K
P
P
A
P
P
N
Site 8
S263
K
P
P
A
P
P
N
S
L
N
V
Q
R
V
L
Site 9
S294
F
D
L
S
G
P
S
S
L
A
Q
P
V
Q
Y
Site 10
Y301
S
L
A
Q
P
V
Q
Y
S
Q
I
R
V
S
G
Site 11
S302
L
A
Q
P
V
Q
Y
S
Q
I
R
V
S
G
P
Site 12
S307
Q
Y
S
Q
I
R
V
S
G
P
R
E
P
A
G
Site 13
S320
A
G
A
P
Q
R
H
S
L
S
E
I
T
Y
L
Site 14
S322
A
P
Q
R
H
S
L
S
E
I
T
Y
L
G
Q
Site 15
Y326
H
S
L
S
E
I
T
Y
L
G
Q
P
D
I
S
Site 16
S333
Y
L
G
Q
P
D
I
S
I
L
Q
P
S
N
V
Site 17
S338
D
I
S
I
L
Q
P
S
N
V
P
P
P
Q
I
Site 18
S347
V
P
P
P
Q
I
L
S
P
L
S
Y
A
P
N
Site 19
S350
P
Q
I
L
S
P
L
S
Y
A
P
N
A
A
P
Site 20
S363
A
P
E
V
G
P
P
S
Y
A
P
Q
V
T
P
Site 21
Y364
P
E
V
G
P
P
S
Y
A
P
Q
V
T
P
E
Site 22
T369
P
S
Y
A
P
Q
V
T
P
E
A
Q
F
P
F
Site 23
Y377
P
E
A
Q
F
P
F
Y
A
P
Q
A
I
S
K
Site 24
S383
F
Y
A
P
Q
A
I
S
K
V
Q
P
S
S
Y
Site 25
S389
I
S
K
V
Q
P
S
S
Y
A
P
Q
A
T
P
Site 26
T395
S
S
Y
A
P
Q
A
T
P
D
S
W
P
P
S
Site 27
S398
A
P
Q
A
T
P
D
S
W
P
P
S
Y
G
V
Site 28
Y403
P
D
S
W
P
P
S
Y
G
V
C
M
E
G
S
Site 29
S410
Y
G
V
C
M
E
G
S
G
K
D
S
P
T
G
Site 30
S414
M
E
G
S
G
K
D
S
P
T
G
T
L
S
S
Site 31
T416
G
S
G
K
D
S
P
T
G
T
L
S
S
P
K
Site 32
T418
G
K
D
S
P
T
G
T
L
S
S
P
K
H
L
Site 33
S420
D
S
P
T
G
T
L
S
S
P
K
H
L
R
P
Site 34
S421
S
P
T
G
T
L
S
S
P
K
H
L
R
P
K
Site 35
S439
Q
K
E
P
P
A
G
S
C
M
L
G
G
L
S
Site 36
S452
L
S
L
Q
E
V
T
S
L
A
M
E
E
S
Q
Site 37
S458
T
S
L
A
M
E
E
S
Q
E
A
K
S
L
H
Site 38
S463
E
E
S
Q
E
A
K
S
L
H
Q
P
L
G
I
Site 39
T472
H
Q
P
L
G
I
C
T
D
R
T
S
D
P
N
Site 40
T475
L
G
I
C
T
D
R
T
S
D
P
N
V
L
H
Site 41
S476
G
I
C
T
D
R
T
S
D
P
N
V
L
H
S
Site 42
S483
S
D
P
N
V
L
H
S
G
E
E
G
T
P
Q
Site 43
T488
L
H
S
G
E
E
G
T
P
Q
Y
L
K
G
Q
Site 44
Y491
G
E
E
G
T
P
Q
Y
L
K
G
Q
L
P
L
Site 45
S500
K
G
Q
L
P
L
L
S
S
V
Q
I
E
G
H
Site 46
S501
G
Q
L
P
L
L
S
S
V
Q
I
E
G
H
P
Site 47
S510
Q
I
E
G
H
P
M
S
L
P
L
Q
P
P
S
Site 48
S517
S
L
P
L
Q
P
P
S
R
P
C
S
P
S
D
Site 49
S521
Q
P
P
S
R
P
C
S
P
S
D
Q
G
P
S
Site 50
S523
P
S
R
P
C
S
P
S
D
Q
G
P
S
P
W
Site 51
S528
S
P
S
D
Q
G
P
S
P
W
G
L
L
E
S
Site 52
S535
S
P
W
G
L
L
E
S
L
V
C
P
K
D
E
Site 53
S545
C
P
K
D
E
A
K
S
P
A
P
E
T
S
D
Site 54
S551
K
S
P
A
P
E
T
S
D
L
E
Q
P
T
E
Site 55
T557
T
S
D
L
E
Q
P
T
E
L
D
S
L
F
R
Site 56
S561
E
Q
P
T
E
L
D
S
L
F
R
G
L
A
L
Site 57
T569
L
F
R
G
L
A
L
T
V
Q
W
E
S
_
_
Site 58
S574
A
L
T
V
Q
W
E
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation