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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAMD3
Full Name:
Sterile alpha motif domain-containing protein 3
Alias:
Type:
Mass (Da):
61237
Number AA:
520
UniProt ID:
Q8N6K7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y63
L
M
D
L
I
K
K
Y
K
Q
N
T
Q
G
L
Site 2
S72
Q
N
T
Q
G
L
K
S
P
E
N
P
K
K
A
Site 3
Y91
Q
T
E
A
A
R
D
Y
R
D
E
E
S
S
S
Site 4
S96
R
D
Y
R
D
E
E
S
S
S
P
A
R
H
G
Site 5
S97
D
Y
R
D
E
E
S
S
S
P
A
R
H
G
E
Site 6
S98
Y
R
D
E
E
S
S
S
P
A
R
H
G
E
Q
Site 7
S108
R
H
G
E
Q
M
P
S
F
Y
P
A
E
N
L
Site 8
Y110
G
E
Q
M
P
S
F
Y
P
A
E
N
L
D
N
Site 9
S146
K
A
L
Q
W
T
K
S
Y
V
L
P
E
F
P
Site 10
Y147
A
L
Q
W
T
K
S
Y
V
L
P
E
F
P
Y
Site 11
T183
E
F
L
Q
A
D
M
T
K
Y
L
E
G
S
L
Site 12
Y185
L
Q
A
D
M
T
K
Y
L
E
G
S
L
Y
P
Site 13
S189
M
T
K
Y
L
E
G
S
L
Y
P
S
T
Q
Q
Site 14
Y191
K
Y
L
E
G
S
L
Y
P
S
T
Q
Q
Y
N
Site 15
S193
L
E
G
S
L
Y
P
S
T
Q
Q
Y
N
D
V
Site 16
T194
E
G
S
L
Y
P
S
T
Q
Q
Y
N
D
V
V
Site 17
Y197
L
Y
P
S
T
Q
Q
Y
N
D
V
V
N
A
L
Site 18
Y231
A
L
K
D
R
F
K
Y
V
R
R
P
I
E
D
Site 19
T256
F
G
H
R
R
G
Q
T
R
K
S
L
A
D
I
Site 20
S259
R
R
G
Q
T
R
K
S
L
A
D
I
R
F
D
Site 21
S282
E
E
A
V
C
F
D
S
E
L
D
E
H
I
K
Site 22
Y295
I
K
W
F
Q
Q
E
Y
V
K
T
E
K
D
W
Site 23
S310
R
E
I
D
K
R
M
S
Q
T
L
E
I
R
R
Site 24
T312
I
D
K
R
M
S
Q
T
L
E
I
R
R
K
M
Site 25
S322
I
R
R
K
M
I
G
S
R
T
P
L
K
D
I
Site 26
T324
R
K
M
I
G
S
R
T
P
L
K
D
I
L
K
Site 27
Y340
F
P
F
L
K
C
P
Y
Q
M
F
R
E
F
Q
Site 28
Y355
L
L
T
R
T
D
I
Y
K
K
T
R
H
I
L
Site 29
S364
K
T
R
H
I
L
E
S
Y
S
E
N
I
L
T
Site 30
S366
R
H
I
L
E
S
Y
S
E
N
I
L
T
S
F
Site 31
T371
S
Y
S
E
N
I
L
T
S
F
S
V
V
D
N
Site 32
S372
Y
S
E
N
I
L
T
S
F
S
V
V
D
N
P
Site 33
Y399
T
D
E
D
M
L
K
Y
M
K
M
T
A
T
C
Site 34
T431
N
E
Q
V
Q
V
S
T
P
V
L
E
V
K
N
Site 35
Y450
E
V
C
E
F
S
L
Y
L
E
R
E
R
L
T
Site 36
T457
Y
L
E
R
E
R
L
T
K
V
D
D
C
V
T
Site 37
S485
I
E
C
P
R
R
L
S
Q
T
F
N
F
L
E
Site 38
T487
C
P
R
R
L
S
Q
T
F
N
F
L
E
T
L
Site 39
Y502
I
F
D
M
H
S
P
Y
F
P
S
L
K
E
K
Site 40
S505
M
H
S
P
Y
F
P
S
L
K
E
K
E
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation