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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAMTSL1
Full Name:
ADAMTS-like protein 1
Alias:
Punctin-1
Type:
Mass (Da):
58416
Number AA:
525
UniProt ID:
Q8N6G6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
L
A
F
L
L
L
S
S
R
T
A
R
S
E
E
Site 2
S28
L
S
S
R
T
A
R
S
E
E
D
R
D
G
L
Site 3
T48
P
W
S
E
C
S
R
T
C
G
G
G
A
S
Y
Site 4
S54
R
T
C
G
G
G
A
S
Y
S
L
R
R
C
L
Site 5
S56
C
G
G
G
A
S
Y
S
L
R
R
C
L
S
S
Site 6
S62
Y
S
L
R
R
C
L
S
S
K
S
C
E
G
R
Site 7
S63
S
L
R
R
C
L
S
S
K
S
C
E
G
R
N
Site 8
S65
R
R
C
L
S
S
K
S
C
E
G
R
N
I
R
Site 9
T75
G
R
N
I
R
Y
R
T
C
S
N
V
D
C
P
Site 10
Y106
V
K
H
H
G
Q
F
Y
E
W
L
P
V
S
N
Site 11
S120
N
D
P
D
N
P
C
S
L
K
C
Q
A
K
G
Site 12
T142
A
P
K
V
L
D
G
T
R
C
Y
T
E
S
L
Site 13
Y145
V
L
D
G
T
R
C
Y
T
E
S
L
D
M
C
Site 14
T146
L
D
G
T
R
C
Y
T
E
S
L
D
M
C
I
Site 15
S183
G
V
C
N
G
D
G
S
T
C
R
L
V
R
G
Site 16
T184
V
C
N
G
D
G
S
T
C
R
L
V
R
G
Q
Site 17
Y192
C
R
L
V
R
G
Q
Y
K
S
Q
L
S
A
T
Site 18
S194
L
V
R
G
Q
Y
K
S
Q
L
S
A
T
K
S
Site 19
S197
G
Q
Y
K
S
Q
L
S
A
T
K
S
D
D
T
Site 20
S201
S
Q
L
S
A
T
K
S
D
D
T
V
V
A
I
Site 21
T204
S
A
T
K
S
D
D
T
V
V
A
I
P
Y
G
Site 22
Y226
L
K
G
P
D
H
L
Y
L
E
T
K
T
L
Q
Site 23
T229
P
D
H
L
Y
L
E
T
K
T
L
Q
G
T
K
Site 24
S240
Q
G
T
K
G
E
N
S
L
S
S
T
G
T
F
Site 25
S242
T
K
G
E
N
S
L
S
S
T
G
T
F
L
V
Site 26
S243
K
G
E
N
S
L
S
S
T
G
T
F
L
V
D
Site 27
T244
G
E
N
S
L
S
S
T
G
T
F
L
V
D
N
Site 28
T246
N
S
L
S
S
T
G
T
F
L
V
D
N
S
S
Site 29
S252
G
T
F
L
V
D
N
S
S
V
D
F
Q
K
F
Site 30
S253
T
F
L
V
D
N
S
S
V
D
F
Q
K
F
P
Site 31
S287
R
N
S
G
S
A
D
S
T
V
Q
F
I
F
Y
Site 32
T288
N
S
G
S
A
D
S
T
V
Q
F
I
F
Y
Q
Site 33
Y317
S
A
T
C
G
G
G
Y
Q
L
T
S
A
E
C
Site 34
Y325
Q
L
T
S
A
E
C
Y
D
L
R
S
N
R
V
Site 35
S329
A
E
C
Y
D
L
R
S
N
R
V
V
A
D
Q
Site 36
Y337
N
R
V
V
A
D
Q
Y
C
H
Y
Y
P
E
N
Site 37
Y341
A
D
Q
Y
C
H
Y
Y
P
E
N
I
K
P
K
Site 38
Y365
P
C
P
A
S
D
G
Y
K
Q
I
M
P
Y
D
Site 39
Y371
G
Y
K
Q
I
M
P
Y
D
L
Y
H
P
L
P
Site 40
Y374
Q
I
M
P
Y
D
L
Y
H
P
L
P
R
W
E
Site 41
T383
P
L
P
R
W
E
A
T
P
W
T
A
C
S
S
Site 42
S390
T
P
W
T
A
C
S
S
S
C
G
G
G
I
Q
Site 43
S391
P
W
T
A
C
S
S
S
C
G
G
G
I
Q
S
Site 44
S402
G
I
Q
S
R
A
V
S
C
V
E
E
D
I
Q
Site 45
T449
A
Q
E
W
S
P
C
T
V
T
C
G
Q
G
L
Site 46
T471
I
D
H
R
G
M
H
T
G
G
C
S
P
K
T
Site 47
S475
G
M
H
T
G
G
C
S
P
K
T
K
P
H
I
Site 48
T478
T
G
G
C
S
P
K
T
K
P
H
I
K
E
E
Site 49
T490
K
E
E
C
I
V
P
T
P
C
Y
K
P
K
E
Site 50
Y493
C
I
V
P
T
P
C
Y
K
P
K
E
K
L
P
Site 51
S521
L
E
E
G
A
A
V
S
E
E
P
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation