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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC5A8
Full Name:
Sodium-coupled monocarboxylate transporter 1
Alias:
Apical iodide transporter;Electrogenic sodium monocarboxylate cotransporter;Sodium iodide-related cotransporter;Solute carrier family 5 member 8
Type:
Mass (Da):
66578
Number AA:
610
UniProt ID:
Q8N695
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
A
G
G
G
Q
Q
T
S
K
D
F
L
M
G
G
Site 2
Y79
L
G
T
P
S
E
V
Y
R
F
G
A
I
F
S
Site 3
T115
Y
K
L
G
I
T
S
T
Y
E
Y
L
E
L
R
Site 4
Y116
K
L
G
I
T
S
T
Y
E
Y
L
E
L
R
F
Site 5
Y118
G
I
T
S
T
Y
E
Y
L
E
L
R
F
N
K
Site 6
Y222
S
T
I
L
N
D
A
Y
D
G
G
R
L
N
F
Site 7
Y257
T
F
T
W
T
S
I
Y
G
V
N
Q
S
Q
V
Site 8
S262
S
I
Y
G
V
N
Q
S
Q
V
Q
R
Y
I
S
Site 9
Y267
N
Q
S
Q
V
Q
R
Y
I
S
C
K
S
R
F
Site 10
S269
S
Q
V
Q
R
Y
I
S
C
K
S
R
F
Q
A
Site 11
S272
Q
R
Y
I
S
C
K
S
R
F
Q
A
K
L
S
Site 12
Y305
G
L
A
L
Y
S
R
Y
H
D
C
D
P
W
T
Site 13
Y372
V
E
D
L
I
K
P
Y
F
R
S
L
S
E
R
Site 14
S375
L
I
K
P
Y
F
R
S
L
S
E
R
S
L
S
Site 15
S377
K
P
Y
F
R
S
L
S
E
R
S
L
S
W
I
Site 16
S380
F
R
S
L
S
E
R
S
L
S
W
I
S
Q
G
Site 17
S382
S
L
S
E
R
S
L
S
W
I
S
Q
G
M
S
Site 18
S385
E
R
S
L
S
W
I
S
Q
G
M
S
V
V
Y
Site 19
Y463
V
G
I
G
A
Q
I
Y
P
P
L
P
E
R
T
Site 20
T493
E
T
N
L
I
T
T
T
E
M
P
F
T
T
S
Site 21
Y505
T
T
S
V
F
Q
I
Y
N
V
Q
R
T
P
L
Site 22
Y517
T
P
L
M
D
N
W
Y
S
L
S
Y
L
Y
F
Site 23
Y521
D
N
W
Y
S
L
S
Y
L
Y
F
S
T
V
G
Site 24
S542
V
G
I
L
V
S
L
S
T
G
G
R
K
Q
N
Site 25
Y554
K
Q
N
L
D
P
R
Y
I
L
T
K
E
D
F
Site 26
T557
L
D
P
R
Y
I
L
T
K
E
D
F
L
S
N
Site 27
S563
L
T
K
E
D
F
L
S
N
F
D
I
F
K
K
Site 28
S576
K
K
K
K
H
V
L
S
Y
K
S
H
P
V
E
Site 29
S579
K
H
V
L
S
Y
K
S
H
P
V
E
D
G
G
Site 30
T587
H
P
V
E
D
G
G
T
D
N
P
A
F
N
H
Site 31
S602
I
E
L
N
S
D
Q
S
G
K
S
N
G
T
R
Site 32
S605
N
S
D
Q
S
G
K
S
N
G
T
R
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation