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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB2
Full Name:
Zinc finger and BTB domain-containing protein 2
Alias:
ZNF437
Type:
Mass (Da):
57337
Number AA:
514
UniProt ID:
Q8N680
International Prot ID:
IPI00166957
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
A
H
K
S
V
L
A
S
F
S
N
Y
F
K
M
Site 2
Y81
S
Y
L
L
H
L
M
Y
T
G
K
M
A
P
Q
Site 3
S115
I
Q
E
A
S
L
A
S
Q
G
A
F
S
H
P
Site 4
S120
L
A
S
Q
G
A
F
S
H
P
D
Q
V
F
P
Site 5
T146
D
H
Q
L
R
Q
A
T
K
I
A
S
A
P
E
Site 6
T163
G
R
D
P
R
P
Q
T
S
R
I
S
Q
E
Q
Site 7
S164
R
D
P
R
P
Q
T
S
R
I
S
Q
E
Q
V
Site 8
S167
R
P
Q
T
S
R
I
S
Q
E
Q
V
P
E
A
Site 9
S175
Q
E
Q
V
P
E
A
S
Q
L
S
Q
L
T
S
Site 10
S178
V
P
E
A
S
Q
L
S
Q
L
T
S
N
L
A
Site 11
S182
S
Q
L
S
Q
L
T
S
N
L
A
Q
V
N
R
Site 12
T193
Q
V
N
R
T
N
M
T
P
S
D
P
L
Q
T
Site 13
S195
N
R
T
N
M
T
P
S
D
P
L
Q
T
S
L
Site 14
S201
P
S
D
P
L
Q
T
S
L
S
P
E
L
V
S
Site 15
S203
D
P
L
Q
T
S
L
S
P
E
L
V
S
T
P
Site 16
S208
S
L
S
P
E
L
V
S
T
P
V
P
P
P
P
Site 17
T209
L
S
P
E
L
V
S
T
P
V
P
P
P
P
P
Site 18
S226
E
T
N
L
E
A
S
S
S
D
E
Q
P
A
S
Site 19
S227
T
N
L
E
A
S
S
S
D
E
Q
P
A
S
L
Site 20
S233
S
S
D
E
Q
P
A
S
L
T
I
A
H
V
K
Site 21
S249
S
I
M
K
R
N
G
S
F
P
K
Y
Y
A
C
Site 22
Y253
R
N
G
S
F
P
K
Y
Y
A
C
H
L
C
G
Site 23
Y254
N
G
S
F
P
K
Y
Y
A
C
H
L
C
G
R
Site 24
T264
H
L
C
G
R
R
F
T
L
R
S
S
L
R
E
Site 25
S267
G
R
R
F
T
L
R
S
S
L
R
E
H
L
Q
Site 26
S268
R
R
F
T
L
R
S
S
L
R
E
H
L
Q
I
Site 27
T277
R
E
H
L
Q
I
H
T
G
V
P
F
T
S
S
Site 28
S283
H
T
G
V
P
F
T
S
S
Q
Q
G
E
S
R
Site 29
S284
T
G
V
P
F
T
S
S
Q
Q
G
E
S
R
V
Site 30
S289
T
S
S
Q
Q
G
E
S
R
V
P
L
T
L
C
Site 31
T294
G
E
S
R
V
P
L
T
L
C
S
N
A
A
D
Site 32
S316
V
P
E
A
G
M
I
S
D
S
E
L
Q
H
I
Site 33
S318
E
A
G
M
I
S
D
S
E
L
Q
H
I
S
D
Site 34
S324
D
S
E
L
Q
H
I
S
D
S
P
I
I
D
G
Site 35
S326
E
L
Q
H
I
S
D
S
P
I
I
D
G
Q
Q
Site 36
S335
I
I
D
G
Q
Q
Q
S
E
T
P
P
P
S
D
Site 37
T337
D
G
Q
Q
Q
S
E
T
P
P
P
S
D
I
A
Site 38
S341
Q
S
E
T
P
P
P
S
D
I
A
D
I
D
N
Site 39
Y363
R
E
V
K
R
R
K
Y
E
C
T
I
C
G
R
Site 40
T386
R
E
H
M
Y
I
H
T
G
K
P
F
K
C
S
Site 41
T394
G
K
P
F
K
C
S
T
C
D
K
S
F
C
R
Site 42
Y418
L
N
Q
S
I
D
T
Y
T
M
V
D
K
Q
T
Site 43
T419
N
Q
S
I
D
T
Y
T
M
V
D
K
Q
T
L
Site 44
T425
Y
T
M
V
D
K
Q
T
L
E
L
C
T
F
E
Site 45
T430
K
Q
T
L
E
L
C
T
F
E
E
G
S
Q
M
Site 46
S435
L
C
T
F
E
E
G
S
Q
M
D
N
M
L
V
Site 47
T456
K
C
N
L
C
D
K
T
F
S
T
P
N
E
V
Site 48
T459
L
C
D
K
T
F
S
T
P
N
E
V
V
K
H
Site 49
S473
H
S
C
Q
N
Q
N
S
D
V
F
A
L
D
E
Site 50
S488
G
R
S
I
L
L
G
S
G
D
S
E
V
T
E
Site 51
S491
I
L
L
G
S
G
D
S
E
V
T
E
P
D
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation