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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NBPF15
Full Name:
Neuroblastoma breakpoint family member 15
Alias:
Type:
Mass (Da):
77563
Number AA:
670
UniProt ID:
Q8N660
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
V
V
S
A
G
P
L
S
S
E
K
A
E
M
N
Site 2
S10
V
S
A
G
P
L
S
S
E
K
A
E
M
N
I
Site 3
Y60
N
R
Q
K
K
Y
K
Y
E
E
C
K
D
L
I
Site 4
Y95
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
A
Q
Site 5
T107
H
A
Q
E
R
E
L
T
Q
L
R
E
K
L
R
Site 6
S120
L
R
E
G
R
D
A
S
R
S
L
N
E
H
L
Site 7
S122
E
G
R
D
A
S
R
S
L
N
E
H
L
Q
A
Site 8
T132
E
H
L
Q
A
L
L
T
P
D
E
P
D
K
S
Site 9
S139
T
P
D
E
P
D
K
S
Q
G
Q
D
L
Q
E
Site 10
T155
L
A
E
G
C
R
L
T
Q
H
L
V
Q
K
L
Site 11
S163
Q
H
L
V
Q
K
L
S
P
E
N
D
N
D
D
Site 12
S185
V
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
Site 13
S186
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
K
Site 14
S203
E
K
E
V
P
E
D
S
L
E
E
C
A
I
T
Site 15
T210
S
L
E
E
C
A
I
T
C
S
N
S
H
G
P
Site 16
Y218
C
S
N
S
H
G
P
Y
D
S
N
Q
P
H
K
Site 17
S220
N
S
H
G
P
Y
D
S
N
Q
P
H
K
K
T
Site 18
T230
P
H
K
K
T
K
I
T
F
E
E
D
K
V
D
Site 19
S238
F
E
E
D
K
V
D
S
T
L
I
G
S
S
S
Site 20
T239
E
E
D
K
V
D
S
T
L
I
G
S
S
S
H
Site 21
S245
S
T
L
I
G
S
S
S
H
V
E
W
E
D
A
Site 22
S273
E
E
E
K
G
P
V
S
P
R
N
L
Q
E
S
Site 23
S280
S
P
R
N
L
Q
E
S
E
E
E
E
V
P
Q
Site 24
S289
E
E
E
V
P
Q
E
S
W
D
E
G
Y
S
T
Site 25
Y294
Q
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
Site 26
S295
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
Site 27
T296
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
M
Site 28
S298
D
E
G
Y
S
T
L
S
I
P
P
E
M
L
A
Site 29
S306
I
P
P
E
M
L
A
S
Y
Q
S
Y
S
S
T
Site 30
Y307
P
P
E
M
L
A
S
Y
Q
S
Y
S
S
T
F
Site 31
S309
E
M
L
A
S
Y
Q
S
Y
S
S
T
F
H
S
Site 32
Y310
M
L
A
S
Y
Q
S
Y
S
S
T
F
H
S
L
Site 33
S311
L
A
S
Y
Q
S
Y
S
S
T
F
H
S
L
E
Site 34
S312
A
S
Y
Q
S
Y
S
S
T
F
H
S
L
E
E
Site 35
T313
S
Y
Q
S
Y
S
S
T
F
H
S
L
E
E
Q
Site 36
S316
S
Y
S
S
T
F
H
S
L
E
E
Q
Q
V
C
Site 37
S349
E
A
T
G
P
R
L
S
R
E
L
L
D
E
K
Site 38
S364
E
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 39
Y369
Q
D
S
L
D
R
C
Y
S
T
P
S
G
C
L
Site 40
S370
D
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
Site 41
T371
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
L
Site 42
S373
D
R
C
Y
S
T
P
S
G
C
L
E
L
T
D
Site 43
T379
P
S
G
C
L
E
L
T
D
S
C
Q
P
Y
R
Site 44
S381
G
C
L
E
L
T
D
S
C
Q
P
Y
R
S
A
Site 45
Y385
L
T
D
S
C
Q
P
Y
R
S
A
F
Y
V
L
Site 46
Y390
Q
P
Y
R
S
A
F
Y
V
L
E
Q
Q
R
V
Site 47
Y409
D
M
D
E
I
E
K
Y
Q
E
V
E
E
D
Q
Site 48
S419
V
E
E
D
Q
D
P
S
C
P
R
L
S
R
E
Site 49
S424
D
P
S
C
P
R
L
S
R
E
L
L
D
E
K
Site 50
Y444
Q
D
S
L
D
R
C
Y
S
T
P
S
D
Y
L
Site 51
S445
D
S
L
D
R
C
Y
S
T
P
S
D
Y
L
E
Site 52
T446
S
L
D
R
C
Y
S
T
P
S
D
Y
L
E
L
Site 53
S448
D
R
C
Y
S
T
P
S
D
Y
L
E
L
P
D
Site 54
Y450
C
Y
S
T
P
S
D
Y
L
E
L
P
D
L
G
Site 55
Y460
L
P
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
Site 56
S461
P
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
E
Site 57
S462
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
E
E
Site 58
S466
P
Y
S
S
A
V
Y
S
L
E
E
Q
Y
L
G
Site 59
S499
G
P
P
C
P
R
L
S
R
E
L
L
E
V
V
Site 60
Y519
Q
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
Site 61
S520
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Site 62
T521
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Q
Site 63
S524
R
C
Y
S
T
P
S
S
C
L
E
Q
P
D
S
Site 64
S531
S
C
L
E
Q
P
D
S
C
Q
P
Y
G
S
S
Site 65
Y535
Q
P
D
S
C
Q
P
Y
G
S
S
F
Y
A
L
Site 66
S538
S
C
Q
P
Y
G
S
S
F
Y
A
L
E
E
K
Site 67
S550
E
E
K
H
V
G
F
S
L
D
V
G
E
I
E
Site 68
S570
K
K
R
R
G
R
R
S
K
K
K
R
R
R
G
Site 69
Y592
N
P
P
C
P
R
L
Y
G
V
L
M
E
V
E
Site 70
Y612
Q
D
S
L
D
R
C
Y
S
T
P
S
M
Y
F
Site 71
S613
D
S
L
D
R
C
Y
S
T
P
S
M
Y
F
E
Site 72
T614
S
L
D
R
C
Y
S
T
P
S
M
Y
F
E
Q
Site 73
Y618
C
Y
S
T
P
S
M
Y
F
E
Q
P
D
S
F
Site 74
Y628
Q
P
D
S
F
Q
H
Y
R
S
V
F
Y
S
F
Site 75
S630
D
S
F
Q
H
Y
R
S
V
F
Y
S
F
E
E
Site 76
S634
H
Y
R
S
V
F
Y
S
F
E
E
E
H
I
S
Site 77
S641
S
F
E
E
E
H
I
S
F
A
L
Y
V
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation