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Updated November 2019
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Protein Info
Short Name:
C10orf12
Full Name:
Uncharacterized protein C10orf12
Alias:
chromosome 10 open reading frame 12; CJ012; DKFZP564P1916; FLJ13022; LOC26148
Type:
Unknown function
Mass (Da):
137223
Number AA:
1247
UniProt ID:
Q8N655
International Prot ID:
IPI00166933
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
Q
S
S
A
L
V
E
S
L
I
T
V
K
M
A
Site 2
S20
V
K
M
A
A
E
N
S
E
E
G
N
T
C
I
Site 3
T25
E
N
S
E
E
G
N
T
C
I
I
P
Q
R
N
Site 4
S38
R
N
L
F
K
A
L
S
E
E
A
W
N
S
G
Site 5
S44
L
S
E
E
A
W
N
S
G
F
M
G
N
S
S
Site 6
S50
N
S
G
F
M
G
N
S
S
R
T
A
D
K
E
Site 7
S51
S
G
F
M
G
N
S
S
R
T
A
D
K
E
N
Site 8
T65
N
T
L
Q
C
P
K
T
P
L
R
Q
D
L
E
Site 9
S88
K
Q
E
N
H
L
H
S
L
G
R
N
K
V
G
Site 10
Y96
L
G
R
N
K
V
G
Y
H
L
H
P
S
D
K
Site 11
S109
D
K
G
Q
F
D
H
S
K
D
G
W
L
G
P
Site 12
T132
A
A
N
G
H
S
R
T
K
M
I
S
T
S
I
Site 13
S136
H
S
R
T
K
M
I
S
T
S
I
K
T
A
R
Site 14
T141
M
I
S
T
S
I
K
T
A
R
K
S
K
R
A
Site 15
S145
S
I
K
T
A
R
K
S
K
R
A
S
G
L
R
Site 16
S149
A
R
K
S
K
R
A
S
G
L
R
I
N
D
Y
Site 17
Y156
S
G
L
R
I
N
D
Y
D
N
Q
C
D
V
V
Site 18
Y164
D
N
Q
C
D
V
V
Y
I
S
Q
P
I
T
E
Site 19
S179
C
H
F
E
N
Q
K
S
I
L
S
S
R
K
T
Site 20
S182
E
N
Q
K
S
I
L
S
S
R
K
T
A
R
K
Site 21
S183
N
Q
K
S
I
L
S
S
R
K
T
A
R
K
S
Site 22
T186
S
I
L
S
S
R
K
T
A
R
K
S
T
R
G
Site 23
S190
S
R
K
T
A
R
K
S
T
R
G
Y
F
F
N
Site 24
T191
R
K
T
A
R
K
S
T
R
G
Y
F
F
N
G
Site 25
Y194
A
R
K
S
T
R
G
Y
F
F
N
G
D
C
C
Site 26
T205
G
D
C
C
E
L
P
T
V
R
T
L
A
R
N
Site 27
T208
C
E
L
P
T
V
R
T
L
A
R
N
L
H
S
Site 28
S215
T
L
A
R
N
L
H
S
Q
E
K
A
S
C
S
Site 29
S220
L
H
S
Q
E
K
A
S
C
S
A
L
A
S
E
Site 30
S222
S
Q
E
K
A
S
C
S
A
L
A
S
E
A
V
Site 31
T237
F
T
P
K
Q
T
L
T
I
P
A
P
R
H
T
Site 32
T244
T
I
P
A
P
R
H
T
V
D
V
Q
L
P
R
Site 33
T263
E
E
P
S
K
E
I
T
S
H
E
E
G
G
G
Site 34
S264
E
P
S
K
E
I
T
S
H
E
E
G
G
G
D
Site 35
S273
E
E
G
G
G
D
V
S
P
R
K
E
P
Q
E
Site 36
T286
Q
E
P
E
V
C
P
T
K
I
K
P
N
L
S
Site 37
S293
T
K
I
K
P
N
L
S
S
S
P
R
S
E
E
Site 38
S294
K
I
K
P
N
L
S
S
S
P
R
S
E
E
T
Site 39
S295
I
K
P
N
L
S
S
S
P
R
S
E
E
T
T
Site 40
S298
N
L
S
S
S
P
R
S
E
E
T
T
A
S
S
Site 41
T301
S
S
P
R
S
E
E
T
T
A
S
S
L
V
W
Site 42
T302
S
P
R
S
E
E
T
T
A
S
S
L
V
W
P
Site 43
S304
R
S
E
E
T
T
A
S
S
L
V
W
P
L
P
Site 44
S305
S
E
E
T
T
A
S
S
L
V
W
P
L
P
A
Site 45
T325
D
L
P
E
G
G
S
T
V
S
A
P
T
A
S
Site 46
S327
P
E
G
G
S
T
V
S
A
P
T
A
S
G
M
Site 47
S332
T
V
S
A
P
T
A
S
G
M
S
S
P
E
H
Site 48
S336
P
T
A
S
G
M
S
S
P
E
H
N
Q
P
P
Site 49
T349
P
P
V
A
L
L
D
T
E
E
M
S
V
P
Q
Site 50
S353
L
L
D
T
E
E
M
S
V
P
Q
D
C
H
L
Site 51
S363
Q
D
C
H
L
L
P
S
T
E
S
F
S
G
G
Site 52
T364
D
C
H
L
L
P
S
T
E
S
F
S
G
G
V
Site 53
S366
H
L
L
P
S
T
E
S
F
S
G
G
V
S
E
Site 54
S368
L
P
S
T
E
S
F
S
G
G
V
S
E
D
V
Site 55
S372
E
S
F
S
G
G
V
S
E
D
V
I
S
R
P
Site 56
S377
G
V
S
E
D
V
I
S
R
P
H
S
P
P
E
Site 57
S381
D
V
I
S
R
P
H
S
P
P
E
I
V
S
R
Site 58
S387
H
S
P
P
E
I
V
S
R
E
E
S
P
Q
C
Site 59
S391
E
I
V
S
R
E
E
S
P
Q
C
S
E
N
Q
Site 60
S395
R
E
E
S
P
Q
C
S
E
N
Q
S
S
P
M
Site 61
S399
P
Q
C
S
E
N
Q
S
S
P
M
G
L
E
P
Site 62
S400
Q
C
S
E
N
Q
S
S
P
M
G
L
E
P
P
Site 63
S409
M
G
L
E
P
P
M
S
L
G
K
A
E
D
N
Site 64
S418
G
K
A
E
D
N
Q
S
I
S
A
E
V
E
S
Site 65
S420
A
E
D
N
Q
S
I
S
A
E
V
E
S
G
D
Site 66
T428
A
E
V
E
S
G
D
T
Q
E
L
N
V
D
P
Site 67
T442
P
L
L
K
E
S
S
T
F
T
D
E
N
P
S
Site 68
T444
L
K
E
S
S
T
F
T
D
E
N
P
S
E
T
Site 69
S449
T
F
T
D
E
N
P
S
E
T
E
E
S
E
A
Site 70
S454
N
P
S
E
T
E
E
S
E
A
A
G
G
I
G
Site 71
S474
D
G
D
V
K
C
L
S
E
K
D
T
Y
D
T
Site 72
T478
K
C
L
S
E
K
D
T
Y
D
T
S
I
D
S
Site 73
Y479
C
L
S
E
K
D
T
Y
D
T
S
I
D
S
L
Site 74
T481
S
E
K
D
T
Y
D
T
S
I
D
S
L
E
E
Site 75
S482
E
K
D
T
Y
D
T
S
I
D
S
L
E
E
N
Site 76
S485
T
Y
D
T
S
I
D
S
L
E
E
N
L
D
K
Site 77
S503
G
K
K
F
P
E
A
S
D
R
C
L
R
S
Q
Site 78
S509
A
S
D
R
C
L
R
S
Q
L
S
D
S
S
S
Site 79
S512
R
C
L
R
S
Q
L
S
D
S
S
S
A
D
R
Site 80
S514
L
R
S
Q
L
S
D
S
S
S
A
D
R
C
L
Site 81
S515
R
S
Q
L
S
D
S
S
S
A
D
R
C
L
R
Site 82
S516
S
Q
L
S
D
S
S
S
A
D
R
C
L
R
N
Site 83
S525
D
R
C
L
R
N
Q
S
S
D
S
S
S
A
C
Site 84
S526
R
C
L
R
N
Q
S
S
D
S
S
S
A
C
L
Site 85
S528
L
R
N
Q
S
S
D
S
S
S
A
C
L
E
I
Site 86
S529
R
N
Q
S
S
D
S
S
S
A
C
L
E
I
K
Site 87
S530
N
Q
S
S
D
S
S
S
A
C
L
E
I
K
V
Site 88
S542
I
K
V
P
K
N
P
S
A
K
R
S
K
K
E
Site 89
S546
K
N
P
S
A
K
R
S
K
K
E
G
H
P
G
Site 90
T556
E
G
H
P
G
G
T
T
P
K
G
L
L
P
D
Site 91
S564
P
K
G
L
L
P
D
S
F
H
T
E
T
L
E
Site 92
T573
H
T
E
T
L
E
D
T
E
K
P
S
V
N
E
Site 93
S577
L
E
D
T
E
K
P
S
V
N
E
R
P
S
E
Site 94
S583
P
S
V
N
E
R
P
S
E
K
D
A
E
Q
E
Site 95
T601
G
G
I
I
T
R
Q
T
L
K
N
M
L
D
K
Site 96
S620
L
R
G
E
I
F
P
S
R
D
P
I
T
T
A
Site 97
T625
F
P
S
R
D
P
I
T
T
A
G
Q
P
L
P
Site 98
T626
P
S
R
D
P
I
T
T
A
G
Q
P
L
P
G
Site 99
Y639
P
G
E
R
L
E
I
Y
V
Q
S
K
M
D
E
Site 100
S696
T
Q
Q
K
D
D
E
S
D
A
P
C
S
S
L
Site 101
S701
D
E
S
D
A
P
C
S
S
L
G
L
S
S
S
Site 102
S702
E
S
D
A
P
C
S
S
L
G
L
S
S
S
G
Site 103
S706
P
C
S
S
L
G
L
S
S
S
G
S
G
D
A
Site 104
S708
S
S
L
G
L
S
S
S
G
S
G
D
A
A
R
Site 105
S710
L
G
L
S
S
S
G
S
G
D
A
A
R
A
P
Site 106
S719
D
A
A
R
A
P
K
S
V
P
R
P
K
R
L
Site 107
T727
V
P
R
P
K
R
L
T
S
S
T
Y
N
L
R
Site 108
S728
P
R
P
K
R
L
T
S
S
T
Y
N
L
R
H
Site 109
S729
R
P
K
R
L
T
S
S
T
Y
N
L
R
H
A
Site 110
T730
P
K
R
L
T
S
S
T
Y
N
L
R
H
A
H
Site 111
S738
Y
N
L
R
H
A
H
S
L
G
S
L
D
A
S
Site 112
S741
R
H
A
H
S
L
G
S
L
D
A
S
K
V
T
Site 113
S745
S
L
G
S
L
D
A
S
K
V
T
S
E
K
E
Site 114
S749
L
D
A
S
K
V
T
S
E
K
E
A
A
Q
V
Site 115
S767
M
P
K
E
N
G
A
S
E
S
G
D
P
L
D
Site 116
S769
K
E
N
G
A
S
E
S
G
D
P
L
D
E
D
Site 117
T780
L
D
E
D
D
V
D
T
V
V
D
E
Q
P
K
Site 118
Y808
I
A
N
F
N
A
Q
Y
M
K
V
Q
K
G
W
Site 119
T825
L
E
K
E
G
Q
P
T
P
R
A
R
N
K
S
Site 120
S832
T
P
R
A
R
N
K
S
D
K
L
K
E
I
W
Site 121
S841
K
L
K
E
I
W
K
S
K
K
R
S
R
K
C
Site 122
S845
I
W
K
S
K
K
R
S
R
K
C
R
S
S
L
Site 123
S850
K
R
S
R
K
C
R
S
S
L
E
S
Q
K
C
Site 124
S851
R
S
R
K
C
R
S
S
L
E
S
Q
K
C
S
Site 125
S854
K
C
R
S
S
L
E
S
Q
K
C
S
P
V
Q
Site 126
S858
S
L
E
S
Q
K
C
S
P
V
Q
M
L
F
M
Site 127
Y910
V
K
H
P
L
Q
K
Y
A
P
S
S
L
Y
P
Site 128
S913
P
L
Q
K
Y
A
P
S
S
L
Y
P
S
S
L
Site 129
S914
L
Q
K
Y
A
P
S
S
L
Y
P
S
S
L
Q
Site 130
Y916
K
Y
A
P
S
S
L
Y
P
S
S
L
Q
A
E
Site 131
S918
A
P
S
S
L
Y
P
S
S
L
Q
A
E
R
L
Site 132
S919
P
S
S
L
Y
P
S
S
L
Q
A
E
R
L
K
Site 133
T936
L
K
K
F
P
G
A
T
P
A
K
N
N
W
K
Site 134
S964
Q
V
E
P
E
D
G
S
D
V
S
P
G
P
N
Site 135
S967
P
E
D
G
S
D
V
S
P
G
P
N
S
E
D
Site 136
S972
D
V
S
P
G
P
N
S
E
D
S
I
E
E
V
Site 137
S975
P
G
P
N
S
E
D
S
I
E
E
V
K
E
D
Site 138
S985
E
V
K
E
D
R
N
S
H
P
P
A
N
L
P
Site 139
T993
H
P
P
A
N
L
P
T
P
A
S
T
R
I
L
Site 140
S996
A
N
L
P
T
P
A
S
T
R
I
L
R
K
Y
Site 141
Y1003
S
T
R
I
L
R
K
Y
S
N
I
R
G
K
L
Site 142
S1004
T
R
I
L
R
K
Y
S
N
I
R
G
K
L
R
Site 143
S1032
P
D
A
L
A
V
E
S
K
P
S
R
K
S
V
Site 144
S1035
L
A
V
E
S
K
P
S
R
K
S
V
C
I
N
Site 145
S1038
E
S
K
P
S
R
K
S
V
C
I
N
P
L
M
Site 146
S1064
G
F
P
V
K
P
K
S
T
E
G
M
K
G
R
Site 147
S1077
G
R
K
G
K
Q
V
S
E
I
L
P
K
A
E
Site 148
S1087
L
P
K
A
E
V
Q
S
K
R
K
R
T
E
G
Site 149
T1092
V
Q
S
K
R
K
R
T
E
G
S
S
P
P
D
Site 150
S1095
K
R
K
R
T
E
G
S
S
P
P
D
S
K
N
Site 151
S1096
R
K
R
T
E
G
S
S
P
P
D
S
K
N
K
Site 152
S1100
E
G
S
S
P
P
D
S
K
N
K
G
P
T
V
Site 153
T1106
D
S
K
N
K
G
P
T
V
K
A
S
K
E
K
Site 154
S1110
K
G
P
T
V
K
A
S
K
E
K
H
A
D
G
Site 155
T1119
E
K
H
A
D
G
A
T
K
T
P
A
A
K
R
Site 156
T1121
H
A
D
G
A
T
K
T
P
A
A
K
R
P
A
Site 157
S1133
R
P
A
A
R
D
R
S
S
Q
P
P
K
K
T
Site 158
S1134
P
A
A
R
D
R
S
S
Q
P
P
K
K
T
S
Site 159
S1153
K
V
K
I
P
K
K
S
A
G
K
S
C
P
P
Site 160
S1157
P
K
K
S
A
G
K
S
C
P
P
S
R
K
E
Site 161
S1161
A
G
K
S
C
P
P
S
R
K
E
K
E
N
T
Site 162
T1168
S
R
K
E
K
E
N
T
N
K
R
P
S
Q
S
Site 163
S1173
E
N
T
N
K
R
P
S
Q
S
I
A
S
E
T
Site 164
S1175
T
N
K
R
P
S
Q
S
I
A
S
E
T
L
T
Site 165
T1182
S
I
A
S
E
T
L
T
K
P
A
K
Q
K
G
Site 166
S1194
Q
K
G
A
G
E
S
S
S
R
P
Q
K
A
T
Site 167
S1195
K
G
A
G
E
S
S
S
R
P
Q
K
A
T
N
Site 168
T1201
S
S
R
P
Q
K
A
T
N
R
K
Q
S
S
G
Site 169
S1206
K
A
T
N
R
K
Q
S
S
G
K
T
R
A
R
Site 170
T1210
R
K
Q
S
S
G
K
T
R
A
R
P
S
T
K
Site 171
S1215
G
K
T
R
A
R
P
S
T
K
T
P
E
S
S
Site 172
T1216
K
T
R
A
R
P
S
T
K
T
P
E
S
S
A
Site 173
T1218
R
A
R
P
S
T
K
T
P
E
S
S
A
A
Q
Site 174
S1221
P
S
T
K
T
P
E
S
S
A
A
Q
R
K
R
Site 175
S1237
L
K
A
K
L
D
C
S
H
S
K
R
R
R
L
Site 176
S1239
A
K
L
D
C
S
H
S
K
R
R
R
L
D
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation