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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AADAT
Full Name:
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Alias:
2-aminoadipate aminotransferase;2-aminoadipate transaminase;Alpha-aminoadipate aminotransferase;KAT/AadAT;Kynurenine aminotransferase II;Kynurenine--oxoglutarate aminotransferase II;Kynurenine--oxoglutarate transaminase II
Type:
Mass (Da):
47352
Number AA:
425
UniProt ID:
Q8N5Z0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
N
Y
A
R
F
I
T
A
A
S
A
A
R
N
Site 2
S11
A
R
F
I
T
A
A
S
A
A
R
N
P
S
P
Site 3
S17
A
S
A
A
R
N
P
S
P
I
R
T
M
T
D
Site 4
T21
R
N
P
S
P
I
R
T
M
T
D
I
L
S
R
Site 5
T23
P
S
P
I
R
T
M
T
D
I
L
S
R
G
P
Site 6
S27
R
T
M
T
D
I
L
S
R
G
P
K
S
M
I
Site 7
S32
I
L
S
R
G
P
K
S
M
I
S
L
A
G
G
Site 8
S35
R
G
P
K
S
M
I
S
L
A
G
G
L
P
N
Site 9
T60
I
T
V
E
N
G
K
T
I
Q
F
G
E
E
M
Site 10
S75
M
K
R
A
L
Q
Y
S
P
S
A
G
I
P
E
Site 11
S77
R
A
L
Q
Y
S
P
S
A
G
I
P
E
L
L
Site 12
T99
I
K
L
H
N
P
P
T
I
H
Y
P
P
S
Q
Site 13
Y102
H
N
P
P
T
I
H
Y
P
P
S
Q
G
Q
M
Site 14
S143
L
L
D
E
P
A
Y
S
G
T
L
Q
S
L
H
Site 15
S148
A
Y
S
G
T
L
Q
S
L
H
P
L
G
C
N
Site 16
S170
E
S
G
I
V
P
D
S
L
R
D
I
L
S
R
Site 17
S176
D
S
L
R
D
I
L
S
R
W
K
P
E
D
A
Site 18
T190
A
K
N
P
Q
K
N
T
P
K
F
L
Y
T
V
Site 19
Y195
K
N
T
P
K
F
L
Y
T
V
P
N
G
N
N
Site 20
T196
N
T
P
K
F
L
Y
T
V
P
N
G
N
N
P
Site 21
S207
G
N
N
P
T
G
N
S
L
T
S
E
R
K
K
Site 22
S210
P
T
G
N
S
L
T
S
E
R
K
K
E
I
Y
Site 23
Y217
S
E
R
K
K
E
I
Y
E
L
A
R
K
Y
D
Site 24
Y233
L
I
I
E
D
D
P
Y
Y
F
L
Q
F
N
K
Site 25
Y234
I
I
E
D
D
P
Y
Y
F
L
Q
F
N
K
F
Site 26
T245
F
N
K
F
R
V
P
T
F
L
S
M
D
V
D
Site 27
S260
G
R
V
I
R
A
D
S
F
S
K
I
I
S
S
Site 28
Y326
V
D
R
V
I
D
F
Y
S
N
Q
K
D
A
I
Site 29
Y388
M
L
P
G
N
A
F
Y
V
D
S
S
A
P
S
Site 30
S391
G
N
A
F
Y
V
D
S
S
A
P
S
P
Y
L
Site 31
S392
N
A
F
Y
V
D
S
S
A
P
S
P
Y
L
R
Site 32
S395
Y
V
D
S
S
A
P
S
P
Y
L
R
A
S
F
Site 33
Y397
D
S
S
A
P
S
P
Y
L
R
A
S
F
S
S
Site 34
S401
P
S
P
Y
L
R
A
S
F
S
S
A
S
P
E
Site 35
S403
P
Y
L
R
A
S
F
S
S
A
S
P
E
Q
M
Site 36
S404
Y
L
R
A
S
F
S
S
A
S
P
E
Q
M
D
Site 37
S406
R
A
S
F
S
S
A
S
P
E
Q
M
D
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation