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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF10
Full Name:
RING finger protein 10
Alias:
KIAA0262; RIE2; ring finger 10; ring finger protein 10
Type:
Unknown function
Mass (Da):
89908
Number AA:
811
UniProt ID:
Q8N5U6
International Prot ID:
IPI00550496
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
N
A
A
A
T
A
S
D
M
D
K
N
S
G
Site 2
S19
A
S
D
M
D
K
N
S
G
S
N
S
S
S
A
Site 3
S21
D
M
D
K
N
S
G
S
N
S
S
S
A
S
S
Site 4
S23
D
K
N
S
G
S
N
S
S
S
A
S
S
G
S
Site 5
S24
K
N
S
G
S
N
S
S
S
A
S
S
G
S
S
Site 6
S25
N
S
G
S
N
S
S
S
A
S
S
G
S
S
K
Site 7
S27
G
S
N
S
S
S
A
S
S
G
S
S
K
G
Q
Site 8
S28
S
N
S
S
S
A
S
S
G
S
S
K
G
Q
Q
Site 9
S31
S
S
A
S
S
G
S
S
K
G
Q
Q
P
P
R
Site 10
S39
K
G
Q
Q
P
P
R
S
A
S
A
G
P
A
G
Site 11
S41
Q
Q
P
P
R
S
A
S
A
G
P
A
G
E
S
Site 12
S48
S
A
G
P
A
G
E
S
K
P
K
S
D
G
K
Site 13
S52
A
G
E
S
K
P
K
S
D
G
K
N
S
S
G
Site 14
S58
K
S
D
G
K
N
S
S
G
S
K
R
Y
N
R
Site 15
S60
D
G
K
N
S
S
G
S
K
R
Y
N
R
K
R
Site 16
S70
Y
N
R
K
R
E
L
S
Y
P
K
N
E
S
F
Site 17
Y71
N
R
K
R
E
L
S
Y
P
K
N
E
S
F
N
Site 18
S76
L
S
Y
P
K
N
E
S
F
N
N
Q
S
R
R
Site 19
S81
N
E
S
F
N
N
Q
S
R
R
S
S
S
Q
K
Site 20
S84
F
N
N
Q
S
R
R
S
S
S
Q
K
S
K
T
Site 21
S85
N
N
Q
S
R
R
S
S
S
Q
K
S
K
T
F
Site 22
S86
N
Q
S
R
R
S
S
S
Q
K
S
K
T
F
N
Site 23
S89
R
R
S
S
S
Q
K
S
K
T
F
N
K
M
P
Site 24
T91
S
S
S
Q
K
S
K
T
F
N
K
M
P
P
Q
Site 25
S103
P
P
Q
R
G
G
G
S
S
K
L
F
S
S
S
Site 26
S104
P
Q
R
G
G
G
S
S
K
L
F
S
S
S
F
Site 27
S108
G
G
S
S
K
L
F
S
S
S
F
N
G
G
R
Site 28
S109
G
S
S
K
L
F
S
S
S
F
N
G
G
R
R
Site 29
S110
S
S
K
L
F
S
S
S
F
N
G
G
R
R
D
Site 30
S128
E
A
Q
R
A
E
F
S
P
A
Q
F
S
G
P
Site 31
S133
E
F
S
P
A
Q
F
S
G
P
K
K
I
N
L
Site 32
T147
L
N
H
L
L
N
F
T
F
E
P
R
G
Q
T
Site 33
T154
T
F
E
P
R
G
Q
T
G
H
F
E
G
S
G
Site 34
S160
Q
T
G
H
F
E
G
S
G
H
G
S
W
G
K
Site 35
Y196
V
V
S
E
D
Q
D
Y
T
A
H
F
A
D
P
Site 36
T197
V
S
E
D
Q
D
Y
T
A
H
F
A
D
P
D
Site 37
S219
V
E
Q
V
R
I
C
S
H
E
V
P
S
C
P
Site 38
S256
I
L
H
Y
L
S
L
S
E
K
T
W
S
K
C
Site 39
T259
Y
L
S
L
S
E
K
T
W
S
K
C
P
I
C
Site 40
S268
S
K
C
P
I
C
Y
S
S
V
H
K
K
D
L
Site 41
S277
V
H
K
K
D
L
K
S
V
V
A
T
E
S
H
Site 42
T281
D
L
K
S
V
V
A
T
E
S
H
Q
Y
V
V
Site 43
Y286
V
A
T
E
S
H
Q
Y
V
V
G
D
T
I
T
Site 44
T293
Y
V
V
G
D
T
I
T
M
Q
L
M
K
R
E
Site 45
S327
H
L
G
D
E
Q
H
S
Q
Y
S
K
L
L
L
Site 46
T362
Q
L
A
E
E
K
H
T
P
E
S
C
F
I
E
Site 47
S365
E
E
K
H
T
P
E
S
C
F
I
E
A
A
I
Site 48
S383
K
T
R
E
E
A
L
S
G
L
A
G
S
R
R
Site 49
T393
A
G
S
R
R
E
V
T
G
V
V
A
A
L
E
Site 50
Y423
P
R
K
G
V
L
E
Y
L
S
A
F
D
E
E
Site 51
S425
K
G
V
L
E
Y
L
S
A
F
D
E
E
T
T
Site 52
T431
L
S
A
F
D
E
E
T
T
E
V
C
S
L
D
Site 53
T432
S
A
F
D
E
E
T
T
E
V
C
S
L
D
T
Site 54
S436
E
E
T
T
E
V
C
S
L
D
T
P
S
R
P
Site 55
S456
V
E
E
E
E
A
V
S
E
P
E
P
E
G
L
Site 56
S487
G
T
I
C
T
E
S
S
Q
Q
E
P
I
T
K
Site 57
T493
S
S
Q
Q
E
P
I
T
K
S
G
F
T
R
L
Site 58
S495
Q
Q
E
P
I
T
K
S
G
F
T
R
L
S
S
Site 59
T498
P
I
T
K
S
G
F
T
R
L
S
S
S
P
C
Site 60
S501
K
S
G
F
T
R
L
S
S
S
P
C
Y
Y
F
Site 61
S502
S
G
F
T
R
L
S
S
S
P
C
Y
Y
F
Y
Site 62
S503
G
F
T
R
L
S
S
S
P
C
Y
Y
F
Y
Q
Site 63
Y506
R
L
S
S
S
P
C
Y
Y
F
Y
Q
A
E
D
Site 64
Y507
L
S
S
S
P
C
Y
Y
F
Y
Q
A
E
D
G
Site 65
Y509
S
S
P
C
Y
Y
F
Y
Q
A
E
D
G
Q
H
Site 66
Y531
V
R
C
L
V
R
E
Y
G
S
L
E
R
S
P
Site 67
S533
C
L
V
R
E
Y
G
S
L
E
R
S
P
E
K
Site 68
S537
E
Y
G
S
L
E
R
S
P
E
K
I
S
A
T
Site 69
Y551
T
V
V
E
I
A
G
Y
S
M
S
E
D
V
R
Site 70
S554
E
I
A
G
Y
S
M
S
E
D
V
R
Q
R
H
Site 71
Y563
D
V
R
Q
R
H
R
Y
L
S
H
L
P
L
T
Site 72
S565
R
Q
R
H
R
Y
L
S
H
L
P
L
T
C
E
Site 73
Y629
E
N
K
K
Q
G
K
Y
P
E
V
H
I
P
L
Site 74
S647
Q
Q
F
P
A
F
N
S
Y
T
C
S
S
D
S
Site 75
Y648
Q
F
P
A
F
N
S
Y
T
C
S
S
D
S
A
Site 76
T649
F
P
A
F
N
S
Y
T
C
S
S
D
S
A
L
Site 77
S651
A
F
N
S
Y
T
C
S
S
D
S
A
L
G
P
Site 78
S654
S
Y
T
C
S
S
D
S
A
L
G
P
T
S
T
Site 79
S660
D
S
A
L
G
P
T
S
T
E
G
H
G
A
L
Site 80
T661
S
A
L
G
P
T
S
T
E
G
H
G
A
L
S
Site 81
S668
T
E
G
H
G
A
L
S
I
S
P
L
S
R
S
Site 82
S670
G
H
G
A
L
S
I
S
P
L
S
R
S
P
G
Site 83
S673
A
L
S
I
S
P
L
S
R
S
P
G
S
H
A
Site 84
S675
S
I
S
P
L
S
R
S
P
G
S
H
A
D
F
Site 85
S678
P
L
S
R
S
P
G
S
H
A
D
F
L
L
T
Site 86
S688
D
F
L
L
T
P
L
S
P
T
A
S
Q
G
S
Site 87
S692
T
P
L
S
P
T
A
S
Q
G
S
P
S
F
C
Site 88
S695
S
P
T
A
S
Q
G
S
P
S
F
C
V
G
S
Site 89
S697
T
A
S
Q
G
S
P
S
F
C
V
G
S
L
E
Site 90
S702
S
P
S
F
C
V
G
S
L
E
E
D
S
P
F
Site 91
S707
V
G
S
L
E
E
D
S
P
F
P
S
F
A
Q
Site 92
S711
E
E
D
S
P
F
P
S
F
A
Q
M
L
R
V
Site 93
T729
K
A
D
V
W
P
K
T
A
P
K
K
D
E
N
Site 94
S737
A
P
K
K
D
E
N
S
L
V
P
P
A
P
V
Site 95
S746
V
P
P
A
P
V
D
S
D
G
E
S
D
N
S
Site 96
S750
P
V
D
S
D
G
E
S
D
N
S
D
R
V
P
Site 97
S753
S
D
G
E
S
D
N
S
D
R
V
P
V
P
S
Site 98
S760
S
D
R
V
P
V
P
S
F
Q
N
S
F
S
Q
Site 99
S764
P
V
P
S
F
Q
N
S
F
S
Q
A
I
E
A
Site 100
S766
P
S
F
Q
N
S
F
S
Q
A
I
E
A
A
F
Site 101
T781
M
K
L
D
T
P
A
T
S
D
P
L
S
E
E
Site 102
S782
K
L
D
T
P
A
T
S
D
P
L
S
E
E
K
Site 103
S786
P
A
T
S
D
P
L
S
E
E
K
G
G
K
K
Site 104
S804
Q
K
Q
K
L
L
F
S
T
S
V
V
H
T
K
Site 105
S806
Q
K
L
L
F
S
T
S
V
V
H
T
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation