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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM63A
Full Name:
Protein FAM63A
Alias:
FAM63a; Family with sequence similarity 63, member A
Type:
Mass (Da):
51805
Number AA:
469
UniProt ID:
Q8N5J2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
P
D
E
H
P
Q
D
T
D
A
R
D
A
D
G
Site 2
S60
A
D
Q
A
L
L
P
S
Q
C
G
D
N
L
E
Site 3
S68
Q
C
G
D
N
L
E
S
P
L
P
E
A
S
S
Site 4
S74
E
S
P
L
P
E
A
S
S
A
P
P
G
P
T
Site 5
S75
S
P
L
P
E
A
S
S
A
P
P
G
P
T
L
Site 6
S95
V
E
T
I
R
A
C
S
M
P
Q
E
L
P
Q
Site 7
S103
M
P
Q
E
L
P
Q
S
P
R
T
R
Q
P
E
Site 8
T106
E
L
P
Q
S
P
R
T
R
Q
P
E
P
D
F
Site 9
T126
I
P
W
K
G
E
Q
T
P
I
I
T
Q
S
T
Site 10
S163
P
Q
K
E
V
I
T
S
D
E
L
M
A
H
L
Site 11
S176
H
L
G
N
C
L
L
S
I
K
P
Q
E
K
S
Site 12
S183
S
I
K
P
Q
E
K
S
E
G
L
Q
L
N
F
Site 13
T215
L
D
V
N
V
R
F
T
G
V
S
D
F
E
Y
Site 14
S218
N
V
R
F
T
G
V
S
D
F
E
Y
T
P
E
Site 15
Y222
T
G
V
S
D
F
E
Y
T
P
E
C
S
V
F
Site 16
T223
G
V
S
D
F
E
Y
T
P
E
C
S
V
F
D
Site 17
S246
G
W
L
V
D
P
Q
S
P
E
A
V
R
A
V
Site 18
S257
V
R
A
V
G
K
L
S
Y
N
Q
L
V
E
R
Site 19
T267
Q
L
V
E
R
I
I
T
C
K
H
S
S
D
T
Site 20
S272
I
I
T
C
K
H
S
S
D
T
N
L
V
T
E
Site 21
S312
A
A
K
E
G
E
L
S
V
F
F
R
N
N
H
Site 22
T324
N
N
H
F
S
T
M
T
K
H
K
S
H
L
Y
Site 23
S328
S
T
M
T
K
H
K
S
H
L
Y
L
L
V
T
Site 24
Y331
T
K
H
K
S
H
L
Y
L
L
V
T
D
Q
G
Site 25
S367
C
D
S
D
F
H
L
S
H
S
L
G
K
G
P
Site 26
S369
S
D
F
H
L
S
H
S
L
G
K
G
P
G
A
Site 27
S382
G
A
E
G
G
S
G
S
P
E
K
Q
L
Q
V
Site 28
S398
Q
D
Y
L
I
A
L
S
L
Q
Q
Q
Q
P
R
Site 29
T437
A
Q
P
V
R
M
R
T
R
V
L
S
L
Q
G
Site 30
S441
R
M
R
T
R
V
L
S
L
Q
G
R
G
A
T
Site 31
T448
S
L
Q
G
R
G
A
T
S
G
R
P
A
G
E
Site 32
S449
L
Q
G
R
G
A
T
S
G
R
P
A
G
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation