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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLJ22626
Full Name:
NF-kappa-B-activating protein
Alias:
Type:
Uncharacterized protein
Mass (Da):
47138
Number AA:
415
UniProt ID:
Q8N5F7
International Prot ID:
IPI00296934
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
P
V
S
G
S
R
S
P
D
R
Site 2
S7
_
M
A
P
V
S
G
S
R
S
P
D
R
E
A
Site 3
S9
A
P
V
S
G
S
R
S
P
D
R
E
A
S
G
Site 4
S15
R
S
P
D
R
E
A
S
G
S
G
G
R
R
R
Site 5
S17
P
D
R
E
A
S
G
S
G
G
R
R
R
S
S
Site 6
S23
G
S
G
G
R
R
R
S
S
S
K
S
P
K
P
Site 7
S24
S
G
G
R
R
R
S
S
S
K
S
P
K
P
S
Site 8
S25
G
G
R
R
R
S
S
S
K
S
P
K
P
S
K
Site 9
S27
R
R
R
S
S
S
K
S
P
K
P
S
K
S
A
Site 10
S31
S
S
K
S
P
K
P
S
K
S
A
R
S
P
R
Site 11
S33
K
S
P
K
P
S
K
S
A
R
S
P
R
G
R
Site 12
S36
K
P
S
K
S
A
R
S
P
R
G
R
R
S
R
Site 13
S42
R
S
P
R
G
R
R
S
R
S
H
S
C
S
R
Site 14
S44
P
R
G
R
R
S
R
S
H
S
C
S
R
S
G
Site 15
S46
G
R
R
S
R
S
H
S
C
S
R
S
G
D
R
Site 16
S48
R
S
R
S
H
S
C
S
R
S
G
D
R
N
G
Site 17
S50
R
S
H
S
C
S
R
S
G
D
R
N
G
L
T
Site 18
T57
S
G
D
R
N
G
L
T
H
Q
L
G
G
L
S
Site 19
S64
T
H
Q
L
G
G
L
S
Q
G
S
R
N
Q
S
Site 20
S67
L
G
G
L
S
Q
G
S
R
N
Q
S
Y
R
S
Site 21
S71
S
Q
G
S
R
N
Q
S
Y
R
S
R
S
R
S
Site 22
Y72
Q
G
S
R
N
Q
S
Y
R
S
R
S
R
S
R
Site 23
S74
S
R
N
Q
S
Y
R
S
R
S
R
S
R
S
R
Site 24
S76
N
Q
S
Y
R
S
R
S
R
S
R
S
R
E
R
Site 25
S78
S
Y
R
S
R
S
R
S
R
S
R
E
R
P
S
Site 26
S80
R
S
R
S
R
S
R
S
R
E
R
P
S
A
P
Site 27
S85
S
R
S
R
E
R
P
S
A
P
R
G
I
P
F
Site 28
S94
P
R
G
I
P
F
A
S
A
S
S
S
V
Y
Y
Site 29
S98
P
F
A
S
A
S
S
S
V
Y
Y
G
S
Y
S
Site 30
Y100
A
S
A
S
S
S
V
Y
Y
G
S
Y
S
R
P
Site 31
Y101
S
A
S
S
S
V
Y
Y
G
S
Y
S
R
P
Y
Site 32
S103
S
S
S
V
Y
Y
G
S
Y
S
R
P
Y
G
S
Site 33
Y104
S
S
V
Y
Y
G
S
Y
S
R
P
Y
G
S
D
Site 34
S105
S
V
Y
Y
G
S
Y
S
R
P
Y
G
S
D
K
Site 35
Y108
Y
G
S
Y
S
R
P
Y
G
S
D
K
P
W
P
Site 36
S110
S
Y
S
R
P
Y
G
S
D
K
P
W
P
S
L
Site 37
S116
G
S
D
K
P
W
P
S
L
L
D
K
E
R
E
Site 38
S125
L
D
K
E
R
E
E
S
L
R
Q
K
R
L
S
Site 39
S132
S
L
R
Q
K
R
L
S
E
R
E
R
I
G
E
Site 40
S149
A
P
E
V
W
G
L
S
P
K
N
P
E
P
D
Site 41
S157
P
K
N
P
E
P
D
S
D
E
H
T
P
V
E
Site 42
T161
E
P
D
S
D
E
H
T
P
V
E
D
E
E
P
Site 43
S171
E
D
E
E
P
K
K
S
T
T
S
A
S
T
S
Site 44
T172
D
E
E
P
K
K
S
T
T
S
A
S
T
S
E
Site 45
S174
E
P
K
K
S
T
T
S
A
S
T
S
E
E
E
Site 46
S176
K
K
S
T
T
S
A
S
T
S
E
E
E
K
K
Site 47
S178
S
T
T
S
A
S
T
S
E
E
E
K
K
K
K
Site 48
S186
E
E
E
K
K
K
K
S
S
R
S
K
E
R
S
Site 49
S187
E
E
K
K
K
K
S
S
R
S
K
E
R
S
K
Site 50
S189
K
K
K
K
S
S
R
S
K
E
R
S
K
K
R
Site 51
S193
S
S
R
S
K
E
R
S
K
K
R
R
K
K
K
Site 52
S201
K
K
R
R
K
K
K
S
S
K
R
K
H
K
K
Site 53
S202
K
R
R
K
K
K
S
S
K
R
K
H
K
K
Y
Site 54
Y209
S
K
R
K
H
K
K
Y
S
E
D
S
D
S
D
Site 55
S210
K
R
K
H
K
K
Y
S
E
D
S
D
S
D
S
Site 56
S213
H
K
K
Y
S
E
D
S
D
S
D
S
D
S
E
Site 57
S215
K
Y
S
E
D
S
D
S
D
S
D
S
E
T
D
Site 58
S217
S
E
D
S
D
S
D
S
D
S
E
T
D
S
S
Site 59
S219
D
S
D
S
D
S
D
S
E
T
D
S
S
D
E
Site 60
T221
D
S
D
S
D
S
E
T
D
S
S
D
E
D
N
Site 61
S223
D
S
D
S
E
T
D
S
S
D
E
D
N
K
R
Site 62
S224
S
D
S
E
T
D
S
S
D
E
D
N
K
R
R
Site 63
S246
E
K
K
K
K
H
R
S
K
K
Y
K
K
K
R
Site 64
Y249
K
K
H
R
S
K
K
Y
K
K
K
R
S
K
K
Site 65
S254
K
K
Y
K
K
K
R
S
K
K
S
R
K
E
S
Site 66
S257
K
K
K
R
S
K
K
S
R
K
E
S
S
D
S
Site 67
S261
S
K
K
S
R
K
E
S
S
D
S
S
S
K
E
Site 68
S262
K
K
S
R
K
E
S
S
D
S
S
S
K
E
S
Site 69
S264
S
R
K
E
S
S
D
S
S
S
K
E
S
Q
E
Site 70
S265
R
K
E
S
S
D
S
S
S
K
E
S
Q
E
E
Site 71
S266
K
E
S
S
D
S
S
S
K
E
S
Q
E
E
F
Site 72
S269
S
D
S
S
S
K
E
S
Q
E
E
F
L
E
N
Site 73
T282
E
N
P
W
K
D
R
T
K
A
E
E
P
S
D
Site 74
S288
R
T
K
A
E
E
P
S
D
L
I
G
P
E
A
Site 75
T298
I
G
P
E
A
P
K
T
L
T
S
Q
D
D
K
Site 76
S301
E
A
P
K
T
L
T
S
Q
D
D
K
P
L
N
Site 77
Y324
E
G
A
A
M
A
E
Y
V
K
A
G
K
R
I
Site 78
T340
R
R
G
E
I
G
L
T
S
E
E
I
A
S
F
Site 79
S341
R
G
E
I
G
L
T
S
E
E
I
A
S
F
E
Site 80
Y352
A
S
F
E
C
S
G
Y
V
M
S
G
S
R
H
Site 81
S355
E
C
S
G
Y
V
M
S
G
S
R
H
R
R
M
Site 82
S357
S
G
Y
V
M
S
G
S
R
H
R
R
M
E
A
Site 83
Y374
L
R
K
E
N
Q
I
Y
S
A
D
E
K
R
A
Site 84
S375
R
K
E
N
Q
I
Y
S
A
D
E
K
R
A
L
Site 85
S384
D
E
K
R
A
L
A
S
F
N
Q
E
E
R
R
Site 86
S400
R
E
N
K
I
L
A
S
F
R
E
M
V
Y
R
Site 87
T409
R
E
M
V
Y
R
K
T
K
G
K
D
D
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation