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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL6
Full Name:
F-box/LRR-repeat protein 6
Alias:
F-box and leucine-rich repeat protein 6;F-box protein FBL6;FBL6A
Type:
Mass (Da):
58588
Number AA:
539
UniProt ID:
Q8N531
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
P
A
S
R
Q
V
R
R
R
A
Site 2
S21
R
A
A
P
R
P
R
S
A
E
D
W
W
W
D
Site 3
S35
D
R
L
A
P
R
G
S
G
Y
H
L
L
Q
S
Site 4
S50
D
S
M
L
L
V
L
S
E
P
G
P
A
R
P
Site 5
S64
P
R
A
Q
R
R
A
S
R
R
T
P
R
Q
P
Site 6
T67
Q
R
R
A
S
R
R
T
P
R
Q
P
P
R
G
Site 7
S76
R
Q
P
P
R
G
P
S
A
A
A
K
P
K
A
Site 8
T100
P
A
P
A
P
A
P
T
P
T
P
E
E
G
P
Site 9
T102
P
A
P
A
P
T
P
T
P
E
E
G
P
D
A
Site 10
S152
R
R
W
Q
E
A
A
S
Q
P
A
L
W
H
T
Site 11
T159
S
Q
P
A
L
W
H
T
V
T
L
S
S
P
L
Site 12
S194
W
L
M
P
N
R
F
S
Q
L
Q
R
L
T
L
Site 13
T200
F
S
Q
L
Q
R
L
T
L
I
H
W
K
S
Q
Site 14
S256
H
S
L
D
L
Q
H
S
M
V
E
S
T
A
V
Site 15
S272
S
F
L
E
E
A
G
S
R
M
R
K
L
W
L
Site 16
T280
R
M
R
K
L
W
L
T
Y
S
S
Q
T
T
A
Site 17
S282
R
K
L
W
L
T
Y
S
S
Q
T
T
A
I
L
Site 18
S313
S
T
G
I
N
R
N
S
I
P
L
Q
L
P
V
Site 19
S372
S
S
T
C
N
F
V
S
N
E
V
L
G
R
L
Site 20
S383
L
G
R
L
L
H
G
S
P
N
L
R
L
L
D
Site 21
Y418
E
Q
L
H
L
G
L
Y
G
T
S
D
R
L
T
Site 22
S421
H
L
G
L
Y
G
T
S
D
R
L
T
L
A
K
Site 23
T425
Y
G
T
S
D
R
L
T
L
A
K
E
G
S
P
Site 24
S431
L
T
L
A
K
E
G
S
P
F
L
T
Q
K
W
Site 25
T435
K
E
G
S
P
F
L
T
Q
K
W
C
H
T
L
Site 26
T441
L
T
Q
K
W
C
H
T
L
R
E
L
D
L
S
Site 27
S448
T
L
R
E
L
D
L
S
G
Q
G
F
S
E
K
Site 28
T467
A
L
A
A
F
L
S
T
P
G
G
S
H
P
A
Site 29
S477
G
S
H
P
A
L
C
S
L
N
L
R
G
T
R
Site 30
T483
C
S
L
N
L
R
G
T
R
V
T
P
S
T
V
Site 31
T486
N
L
R
G
T
R
V
T
P
S
T
V
S
S
V
Site 32
S488
R
G
T
R
V
T
P
S
T
V
S
S
V
I
S
Site 33
T489
G
T
R
V
T
P
S
T
V
S
S
V
I
S
S
Site 34
Y519
P
R
G
L
K
R
A
Y
R
G
L
E
E
V
Q
Site 35
T534
W
C
L
E
Q
L
L
T
S
P
S
P
S
_
_
Site 36
S535
C
L
E
Q
L
L
T
S
P
S
P
S
_
_
_
Site 37
S537
E
Q
L
L
T
S
P
S
P
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation