KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PRR18
Full Name:
Proline-rich protein 18
Alias:
Type:
Mass (Da):
30926
Number AA:
295
UniProt ID:
Q8N4B5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
Q
R
P
E
G
L
L
S
S
S
W
P
S
A
T
Site 2
S46
R
P
E
G
L
L
S
S
S
W
P
S
A
T
L
Site 3
S47
P
E
G
L
L
S
S
S
W
P
S
A
T
L
K
Site 4
S50
L
L
S
S
S
W
P
S
A
T
L
K
R
P
P
Site 5
T52
S
S
S
W
P
S
A
T
L
K
R
P
P
A
R
Site 6
T67
R
G
P
G
L
D
R
T
Q
P
P
A
P
P
G
Site 7
S76
P
P
A
P
P
G
V
S
P
Q
A
L
P
S
R
Site 8
S82
V
S
P
Q
A
L
P
S
R
A
R
A
P
A
T
Site 9
T89
S
R
A
R
A
P
A
T
C
A
P
P
R
P
A
Site 10
S98
A
P
P
R
P
A
G
S
G
H
S
P
A
R
T
Site 11
S101
R
P
A
G
S
G
H
S
P
A
R
T
T
Y
A
Site 12
T105
S
G
H
S
P
A
R
T
T
Y
A
A
T
S
A
Site 13
T106
G
H
S
P
A
R
T
T
Y
A
A
T
S
A
G
Site 14
Y107
H
S
P
A
R
T
T
Y
A
A
T
S
A
G
T
Site 15
S123
T
T
A
A
G
T
S
S
G
A
G
P
C
P
D
Site 16
S131
G
A
G
P
C
P
D
S
A
A
R
F
S
L
N
Site 17
S136
P
D
S
A
A
R
F
S
L
N
L
T
P
E
A
Site 18
S166
R
P
R
R
P
F
P
S
P
S
A
E
P
R
R
Site 19
S168
R
R
P
F
P
S
P
S
A
E
P
R
R
L
L
Site 20
S193
P
R
R
G
G
P
A
S
D
P
D
A
P
P
T
Site 21
T200
S
D
P
D
A
P
P
T
A
G
Q
G
R
R
A
Site 22
S225
G
L
Q
V
P
Q
L
S
P
R
P
G
A
L
R
Site 23
Y246
L
L
N
E
R
H
R
Y
D
D
V
E
Y
E
E
Site 24
Y251
H
R
Y
D
D
V
E
Y
E
E
E
P
E
A
V
Site 25
T267
E
G
L
V
R
K
C
T
E
W
L
R
G
V
E
Site 26
S288
G
R
A
G
A
L
D
S
R
R
H
L
S
T
L
Site 27
T294
D
S
R
R
H
L
S
T
L
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation