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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPXM2
Full Name:
Inactive carboxypeptidase-like protein X2
Alias:
Type:
Mass (Da):
85870
Number AA:
756
UniProt ID:
Q8N436
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y35
A
A
L
E
D
P
D
Y
Y
G
Q
E
I
W
S
Site 2
Y36
A
L
E
D
P
D
Y
Y
G
Q
E
I
W
S
R
Site 3
Y46
E
I
W
S
R
E
P
Y
Y
A
R
P
E
P
E
Site 4
Y47
I
W
S
R
E
P
Y
Y
A
R
P
E
P
E
L
Site 5
T56
R
P
E
P
E
L
E
T
F
S
P
P
L
P
A
Site 6
S58
E
P
E
L
E
T
F
S
P
P
L
P
A
G
P
Site 7
T83
P
R
P
P
K
R
A
T
K
P
K
K
A
P
K
Site 8
S94
K
A
P
K
R
E
K
S
A
P
E
P
P
P
P
Site 9
T112
S
N
K
K
V
M
R
T
K
S
S
E
K
A
A
Site 10
S114
K
K
V
M
R
T
K
S
S
E
K
A
A
N
D
Site 11
S124
K
A
A
N
D
D
H
S
V
R
V
A
R
E
D
Site 12
S135
A
R
E
D
V
R
E
S
C
P
P
L
G
L
E
Site 13
T155
D
F
Q
L
H
A
S
T
V
K
R
Y
G
L
G
Site 14
Y180
G
I
N
E
N
D
F
Y
D
G
A
W
C
A
G
Site 15
T203
E
V
D
A
R
R
L
T
R
F
T
G
V
I
T
Site 16
T206
A
R
R
L
T
R
F
T
G
V
I
T
Q
G
R
Site 17
T210
T
R
F
T
G
V
I
T
Q
G
R
N
S
L
W
Site 18
S219
G
R
N
S
L
W
L
S
D
W
V
T
S
Y
K
Site 19
Y225
L
S
D
W
V
T
S
Y
K
V
M
V
S
N
D
Site 20
T235
M
V
S
N
D
S
H
T
W
V
T
V
K
N
G
Site 21
T238
N
D
S
H
T
W
V
T
V
K
N
G
S
G
D
Site 22
Y270
P
V
P
M
V
A
R
Y
I
R
I
N
P
Q
S
Site 23
Y301
P
L
P
D
P
N
N
Y
Y
H
R
R
N
E
M
Site 24
Y302
L
P
D
P
N
N
Y
Y
H
R
R
N
E
M
T
Site 25
T309
Y
H
R
R
N
E
M
T
T
T
D
D
L
D
F
Site 26
T310
H
R
R
N
E
M
T
T
T
D
D
L
D
F
K
Site 27
T311
R
R
N
E
M
T
T
T
D
D
L
D
F
K
H
Site 28
Y321
L
D
F
K
H
H
N
Y
K
E
M
R
Q
L
M
Site 29
Y342
C
P
N
I
T
R
I
Y
N
I
G
K
S
H
Q
Site 30
Y354
S
H
Q
G
L
K
L
Y
A
V
E
I
S
D
H
Site 31
S359
K
L
Y
A
V
E
I
S
D
H
P
G
E
H
E
Site 32
Y374
V
G
E
P
E
F
H
Y
I
A
G
A
H
G
N
Site 33
S421
T
R
I
H
V
L
P
S
L
N
P
D
G
Y
E
Site 34
Y427
P
S
L
N
P
D
G
Y
E
K
A
Y
E
G
G
Site 35
Y431
P
D
G
Y
E
K
A
Y
E
G
G
S
E
L
G
Site 36
S435
E
K
A
Y
E
G
G
S
E
L
G
G
W
S
L
Site 37
S441
G
S
E
L
G
G
W
S
L
G
R
W
T
H
D
Site 38
Y480
P
R
K
V
P
N
H
Y
I
A
I
P
E
W
F
Site 39
T493
W
F
L
S
E
N
A
T
V
A
A
E
T
R
A
Site 40
S532
Y
P
Y
D
L
V
R
S
P
W
K
T
Q
E
H
Site 41
T536
L
V
R
S
P
W
K
T
Q
E
H
T
P
T
P
Site 42
T540
P
W
K
T
Q
E
H
T
P
T
P
D
D
H
V
Site 43
T542
K
T
Q
E
H
T
P
T
P
D
D
H
V
F
R
Site 44
S554
V
F
R
W
L
A
Y
S
Y
A
S
T
H
R
L
Site 45
T558
L
A
Y
S
Y
A
S
T
H
R
L
M
T
D
A
Site 46
T563
A
S
T
H
R
L
M
T
D
A
R
R
R
V
C
Site 47
T572
A
R
R
R
V
C
H
T
E
D
F
Q
K
E
E
Site 48
T581
D
F
Q
K
E
E
G
T
V
N
G
A
S
W
H
Site 49
S586
E
G
T
V
N
G
A
S
W
H
T
V
A
G
S
Site 50
T589
V
N
G
A
S
W
H
T
V
A
G
S
L
N
D
Site 51
S593
S
W
H
T
V
A
G
S
L
N
D
F
S
Y
L
Site 52
Y599
G
S
L
N
D
F
S
Y
L
H
T
N
C
F
E
Site 53
Y610
N
C
F
E
L
S
I
Y
V
G
C
D
K
Y
P
Site 54
Y616
I
Y
V
G
C
D
K
Y
P
H
E
S
Q
L
P
Site 55
S651
I
K
G
L
V
R
D
S
H
G
K
G
I
P
N
Site 56
Y678
R
T
A
N
D
G
D
Y
W
R
L
L
N
P
G
Site 57
Y687
R
L
L
N
P
G
E
Y
V
V
T
A
K
A
E
Site 58
T690
N
P
G
E
Y
V
V
T
A
K
A
E
G
F
T
Site 59
S699
K
A
E
G
F
T
A
S
T
K
N
C
M
V
G
Site 60
T717
G
A
T
R
C
D
F
T
L
S
K
T
N
M
A
Site 61
S739
K
F
G
K
Q
P
V
S
L
P
A
R
R
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation