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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VWA5B2
Full Name:
von Willebrand factor A domain-containing protein 5B2
Alias:
Type:
Mass (Da):
132764
Number AA:
1253
UniProt ID:
Q8N398
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
P
G
L
Y
C
P
S
S
W
T
P
L
P
L
T
Site 2
T11
L
Y
C
P
S
S
W
T
P
L
P
L
T
D
S
Site 3
T16
S
W
T
P
L
P
L
T
D
S
W
V
R
A
C
Site 4
S18
T
P
L
P
L
T
D
S
W
V
R
A
C
A
N
Site 5
T36
L
S
V
R
A
R
L
T
Y
R
N
P
Q
P
Q
Site 6
Y37
S
V
R
A
R
L
T
Y
R
N
P
Q
P
Q
P
Site 7
S72
E
A
A
G
R
R
V
S
F
Q
L
Q
S
R
R
Site 8
S77
R
V
S
F
Q
L
Q
S
R
R
R
S
Q
A
A
Site 9
S81
Q
L
Q
S
R
R
R
S
Q
A
A
C
C
R
A
Site 10
T95
A
L
G
P
G
L
G
T
P
T
P
R
R
C
A
Site 11
T97
G
P
G
L
G
T
P
T
P
R
R
C
A
Q
G
Site 12
T133
A
A
G
T
M
T
V
T
L
H
S
S
R
E
L
Site 13
S136
T
M
T
V
T
L
H
S
S
R
E
L
P
S
R
Site 14
S142
H
S
S
R
E
L
P
S
R
P
D
G
V
L
H
Site 15
S284
L
E
I
L
L
H
P
S
E
P
H
Q
P
H
L
Site 16
S297
H
L
M
L
E
G
G
S
L
S
S
A
E
Y
E
Site 17
S299
M
L
E
G
G
S
L
S
S
A
E
Y
E
A
R
Site 18
Y303
G
S
L
S
S
A
E
Y
E
A
R
V
R
A
R
Site 19
S321
Q
R
L
Q
R
R
D
S
D
G
D
R
Q
V
W
Site 20
S353
L
S
F
C
P
D
L
S
S
K
P
G
H
L
G
Site 21
S354
S
F
C
P
D
L
S
S
K
P
G
H
L
G
T
Site 22
T361
S
K
P
G
H
L
G
T
A
T
R
E
L
L
F
Site 23
S410
V
Q
P
L
F
P
E
S
R
P
C
S
D
D
A
Site 24
S414
F
P
E
S
R
P
C
S
D
D
A
V
Q
L
I
Site 25
Y453
G
Q
P
Q
H
R
A
Y
P
R
Q
L
F
L
L
Site 26
S503
H
Q
L
L
Q
G
L
S
A
L
S
R
G
Q
A
Site 27
Y511
A
L
S
R
G
Q
A
Y
F
L
R
P
G
Q
R
Site 28
S536
K
A
L
E
P
A
L
S
D
I
S
V
D
W
F
Site 29
S539
E
P
A
L
S
D
I
S
V
D
W
F
V
P
D
Site 30
T547
V
D
W
F
V
P
D
T
V
E
A
L
L
T
P
Site 31
Y561
P
R
E
I
P
A
L
Y
P
G
D
Q
L
L
G
Site 32
S580
F
R
V
D
G
F
R
S
R
P
P
G
G
Q
E
Site 33
S592
G
Q
E
P
G
W
Q
S
S
G
G
S
V
F
P
Site 34
S593
Q
E
P
G
W
Q
S
S
G
G
S
V
F
P
S
Site 35
S596
G
W
Q
S
S
G
G
S
V
F
P
S
P
E
E
Site 36
S600
S
G
G
S
V
F
P
S
P
E
E
A
P
S
A
Site 37
S606
P
S
P
E
E
A
P
S
A
A
S
P
G
T
E
Site 38
S609
E
E
A
P
S
A
A
S
P
G
T
E
P
T
G
Site 39
T617
P
G
T
E
P
T
G
T
S
E
P
L
G
T
G
Site 40
T623
G
T
S
E
P
L
G
T
G
T
V
S
A
E
L
Site 41
T625
S
E
P
L
G
T
G
T
V
S
A
E
L
S
S
Site 42
S627
P
L
G
T
G
T
V
S
A
E
L
S
S
P
W
Site 43
S631
G
T
V
S
A
E
L
S
S
P
W
A
A
R
D
Site 44
S632
T
V
S
A
E
L
S
S
P
W
A
A
R
D
S
Site 45
S639
S
P
W
A
A
R
D
S
E
Q
S
T
D
A
L
Site 46
S642
A
A
R
D
S
E
Q
S
T
D
A
L
T
D
P
Site 47
T643
A
R
D
S
E
Q
S
T
D
A
L
T
D
P
V
Site 48
T647
E
Q
S
T
D
A
L
T
D
P
V
T
D
P
G
Site 49
T651
D
A
L
T
D
P
V
T
D
P
G
P
N
P
S
Site 50
S658
T
D
P
G
P
N
P
S
D
T
A
I
W
R
R
Site 51
T660
P
G
P
N
P
S
D
T
A
I
W
R
R
I
F
Site 52
Y671
R
R
I
F
Q
S
S
Y
I
R
E
Q
Y
V
L
Site 53
Y676
S
S
Y
I
R
E
Q
Y
V
L
T
H
C
S
A
Site 54
T679
I
R
E
Q
Y
V
L
T
H
C
S
A
S
P
E
Site 55
S682
Q
Y
V
L
T
H
C
S
A
S
P
E
P
G
P
Site 56
S684
V
L
T
H
C
S
A
S
P
E
P
G
P
G
S
Site 57
S691
S
P
E
P
G
P
G
S
T
G
S
S
E
S
P
Site 58
T692
P
E
P
G
P
G
S
T
G
S
S
E
S
P
G
Site 59
S694
P
G
P
G
S
T
G
S
S
E
S
P
G
S
Q
Site 60
S695
G
P
G
S
T
G
S
S
E
S
P
G
S
Q
G
Site 61
S697
G
S
T
G
S
S
E
S
P
G
S
Q
G
P
G
Site 62
S700
G
S
S
E
S
P
G
S
Q
G
P
G
S
P
E
Site 63
S705
P
G
S
Q
G
P
G
S
P
E
G
S
A
P
L
Site 64
S709
G
P
G
S
P
E
G
S
A
P
L
E
P
P
S
Site 65
S716
S
A
P
L
E
P
P
S
Q
Q
G
C
R
S
L
Site 66
S722
P
S
Q
Q
G
C
R
S
L
A
W
G
E
P
A
Site 67
S731
A
W
G
E
P
A
G
S
R
S
C
P
L
P
A
Site 68
S733
G
E
P
A
G
S
R
S
C
P
L
P
A
P
T
Site 69
S750
P
F
K
V
G
A
L
S
T
E
V
L
G
R
Q
Site 70
T751
F
K
V
G
A
L
S
T
E
V
L
G
R
Q
H
Site 71
S766
R
A
A
L
A
G
R
S
L
S
S
P
P
G
R
Site 72
S768
A
L
A
G
R
S
L
S
S
P
P
G
R
A
N
Site 73
S769
L
A
G
R
S
L
S
S
P
P
G
R
A
N
Q
Site 74
S785
P
G
R
P
R
K
P
S
L
G
A
I
L
D
G
Site 75
S794
G
A
I
L
D
G
P
S
P
E
P
G
Q
Q
L
Site 76
S808
L
G
Q
G
L
D
D
S
G
N
L
L
S
P
A
Site 77
S813
D
D
S
G
N
L
L
S
P
A
P
M
D
W
D
Site 78
S881
L
W
G
P
G
D
G
S
Q
P
P
S
P
P
V
Site 79
S885
G
D
G
S
Q
P
P
S
P
P
V
R
E
A
A
Site 80
T901
D
Q
A
L
H
R
L
T
A
A
S
V
V
R
D
Site 81
S904
L
H
R
L
T
A
A
S
V
V
R
D
N
E
Q
Site 82
T920
A
L
R
G
G
A
E
T
T
A
D
R
G
H
A
Site 83
T937
C
W
L
R
A
L
Q
T
S
K
V
S
S
A
P
Site 84
S938
W
L
R
A
L
Q
T
S
K
V
S
S
A
P
S
Site 85
S969
P
G
A
L
Q
V
C
S
S
E
P
A
E
P
P
Site 86
S970
G
A
L
Q
V
C
S
S
E
P
A
E
P
P
G
Site 87
T978
E
P
A
E
P
P
G
T
P
P
A
S
H
S
H
Site 88
S982
P
P
G
T
P
P
A
S
H
S
H
L
D
A
A
Site 89
S984
G
T
P
P
A
S
H
S
H
L
D
A
A
P
L
Site 90
S1004
S
K
G
L
Q
R
G
S
P
A
G
A
W
D
S
Site 91
S1011
S
P
A
G
A
W
D
S
D
Q
N
G
N
S
K
Site 92
S1017
D
S
D
Q
N
G
N
S
K
R
A
L
G
D
P
Site 93
T1026
R
A
L
G
D
P
A
T
P
T
E
G
P
R
R
Site 94
T1028
L
G
D
P
A
T
P
T
E
G
P
R
R
P
P
Site 95
S1043
P
R
P
P
C
R
L
S
M
G
R
R
H
K
L
Site 96
S1052
G
R
R
H
K
L
C
S
P
D
P
G
Q
A
N
Site 97
Y1068
S
E
G
S
D
H
D
Y
L
P
L
V
R
L
Q
Site 98
S1080
R
L
Q
E
A
P
G
S
F
R
L
D
A
P
F
Site 99
S1102
Q
E
R
L
C
R
A
S
P
F
A
V
H
R
A
Site 100
S1110
P
F
A
V
H
R
A
S
L
S
P
T
S
A
S
Site 101
S1112
A
V
H
R
A
S
L
S
P
T
S
A
S
L
P
Site 102
T1114
H
R
A
S
L
S
P
T
S
A
S
L
P
W
A
Site 103
S1132
P
G
V
G
Q
G
D
S
A
T
A
S
C
S
P
Site 104
T1134
V
G
Q
G
D
S
A
T
A
S
C
S
P
S
P
Site 105
S1136
Q
G
D
S
A
T
A
S
C
S
P
S
P
S
S
Site 106
S1138
D
S
A
T
A
S
C
S
P
S
P
S
S
G
S
Site 107
S1140
A
T
A
S
C
S
P
S
P
S
S
G
S
E
G
Site 108
S1142
A
S
C
S
P
S
P
S
S
G
S
E
G
P
G
Site 109
S1143
S
C
S
P
S
P
S
S
G
S
E
G
P
G
Q
Site 110
S1145
S
P
S
P
S
S
G
S
E
G
P
G
Q
V
D
Site 111
S1153
E
G
P
G
Q
V
D
S
G
R
G
S
D
T
E
Site 112
S1157
Q
V
D
S
G
R
G
S
D
T
E
A
S
E
G
Site 113
T1159
D
S
G
R
G
S
D
T
E
A
S
E
G
A
E
Site 114
S1162
R
G
S
D
T
E
A
S
E
G
A
E
G
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation