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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO1H
Full Name:
Myosin-Ih
Alias:
Myosin-1H
Type:
Mass (Da):
119037
Number AA:
1032
UniProt ID:
Q8N1T3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
D
N
L
R
K
R
F
S
E
N
L
I
Y
T
Y
Site 2
Y42
R
F
S
E
N
L
I
Y
T
Y
I
G
T
L
L
Site 3
Y55
L
L
V
S
V
N
P
Y
Q
E
L
G
I
Y
T
Site 4
Y61
P
Y
Q
E
L
G
I
Y
T
V
S
Q
M
E
L
Site 5
T62
Y
Q
E
L
G
I
Y
T
V
S
Q
M
E
L
Y
Site 6
S64
E
L
G
I
Y
T
V
S
Q
M
E
L
Y
Q
G
Site 7
Y69
T
V
S
Q
M
E
L
Y
Q
G
V
N
F
F
E
Site 8
S104
N
N
H
F
I
L
I
S
G
E
S
G
A
G
K
Site 9
T154
E
A
F
G
N
A
R
T
L
R
N
D
N
S
S
Site 10
S160
R
T
L
R
N
D
N
S
S
R
F
G
K
Y
M
Site 11
S161
T
L
R
N
D
N
S
S
R
F
G
K
Y
M
D
Site 12
Y166
N
S
S
R
F
G
K
Y
M
D
I
Q
F
D
F
Site 13
S184
P
V
G
G
H
I
I
S
Y
L
I
E
K
S
R
Site 14
Y185
V
G
G
H
I
I
S
Y
L
I
E
K
S
R
V
Site 15
Y194
I
E
K
S
R
V
V
Y
Q
N
E
G
E
R
N
Site 16
Y206
E
R
N
F
H
I
F
Y
Q
L
L
A
G
G
E
Site 17
S218
G
G
E
E
E
R
L
S
Y
L
G
L
E
R
D
Site 18
Y219
G
E
E
E
R
L
S
Y
L
G
L
E
R
D
P
Site 19
Y229
L
E
R
D
P
Q
L
Y
K
Y
L
S
Q
G
H
Site 20
Y231
R
D
P
Q
L
Y
K
Y
L
S
Q
G
H
C
A
Site 21
S233
P
Q
L
Y
K
Y
L
S
Q
G
H
C
A
K
E
Site 22
S244
C
A
K
E
S
S
I
S
D
K
N
D
W
K
T
Site 23
T251
S
D
K
N
D
W
K
T
V
S
N
A
F
S
V
Site 24
S312
K
L
L
G
V
H
P
S
V
L
L
E
A
L
T
Site 25
T319
S
V
L
L
E
A
L
T
H
R
K
I
E
A
K
Site 26
T354
A
K
A
V
Y
G
R
T
F
T
W
L
V
N
K
Site 27
Y431
L
K
A
E
Q
A
E
Y
E
M
E
G
I
E
W
Site 28
Y443
I
E
W
E
P
I
K
Y
F
N
N
K
I
I
C
Site 29
S462
E
R
H
K
G
I
I
S
I
L
D
E
E
C
I
Site 30
T475
C
I
R
P
G
P
A
T
D
L
S
F
L
E
K
Site 31
S478
P
G
P
A
T
D
L
S
F
L
E
K
L
E
E
Site 32
Y537
E
K
N
N
D
L
L
Y
R
H
L
K
E
V
L
Site 33
S547
L
K
E
V
L
C
K
S
K
N
I
I
L
R
E
Site 34
T569
E
N
R
R
R
P
P
T
V
G
T
Q
F
K
N
Site 35
T572
R
R
P
P
T
V
G
T
Q
F
K
N
S
L
S
Site 36
S577
V
G
T
Q
F
K
N
S
L
S
S
L
L
E
T
Site 37
S579
T
Q
F
K
N
S
L
S
S
L
L
E
T
L
I
Site 38
T584
S
L
S
S
L
L
E
T
L
I
S
K
E
P
S
Site 39
S587
S
L
L
E
T
L
I
S
K
E
P
S
Y
I
R
Site 40
S591
T
L
I
S
K
E
P
S
Y
I
R
C
I
K
P
Site 41
Y592
L
I
S
K
E
P
S
Y
I
R
C
I
K
P
N
Site 42
Y618
L
I
R
H
Q
I
K
Y
L
G
L
M
E
H
L
Site 43
Y634
V
R
R
A
G
F
A
Y
R
R
K
Y
E
H
F
Site 44
Y638
G
F
A
Y
R
R
K
Y
E
H
F
L
Q
R
Y
Site 45
Y645
Y
E
H
F
L
Q
R
Y
K
S
L
C
P
D
T
Site 46
Y670
G
V
E
R
L
I
K
Y
I
G
Y
K
P
E
E
Site 47
Y678
I
G
Y
K
P
E
E
Y
K
L
G
K
T
K
I
Site 48
T696
F
P
R
T
L
F
A
T
E
D
A
F
E
F
S
Site 49
Y715
V
A
R
I
Q
A
T
Y
K
R
C
L
G
R
R
Site 50
Y724
R
C
L
G
R
R
E
Y
V
K
K
R
Q
A
A
Site 51
S766
K
F
I
K
G
F
I
S
R
N
K
P
L
C
P
Site 52
Y792
N
Y
I
L
N
L
R
Y
H
L
P
K
T
V
L
Site 53
T797
L
R
Y
H
L
P
K
T
V
L
D
K
S
W
L
Site 54
S802
P
K
T
V
L
D
K
S
W
L
R
P
P
G
I
Site 55
Y829
V
R
N
L
V
Q
K
Y
C
R
G
I
T
A
E
Site 56
T834
Q
K
Y
C
R
G
I
T
A
E
R
K
A
M
M
Site 57
Y858
F
R
G
R
K
D
G
Y
T
E
S
L
N
Q
P
Site 58
T859
R
G
R
K
D
G
Y
T
E
S
L
N
Q
P
F
Site 59
S861
R
K
D
G
Y
T
E
S
L
N
Q
P
F
V
N
Site 60
S885
P
K
V
L
Q
L
I
S
H
E
K
I
Q
Y
G
Site 61
Y891
I
S
H
E
K
I
Q
Y
G
V
P
V
I
K
Y
Site 62
Y898
Y
G
V
P
V
I
K
Y
D
R
K
G
F
K
A
Site 63
T913
R
Q
R
Q
L
I
L
T
Q
K
A
A
Y
V
V
Site 64
S938
Y
S
A
L
K
G
V
S
T
S
N
L
S
D
G
Site 65
T939
S
A
L
K
G
V
S
T
S
N
L
S
D
G
I
Site 66
S952
G
I
L
V
I
H
V
S
P
E
D
S
K
Q
K
Site 67
S956
I
H
V
S
P
E
D
S
K
Q
K
G
D
A
V
Site 68
T1009
E
G
T
I
V
F
D
T
G
L
E
E
Q
V
Y
Site 69
Y1016
T
G
L
E
E
Q
V
Y
K
N
K
N
G
Q
L
Site 70
T1024
K
N
K
N
G
Q
L
T
V
V
S
V
R
R
K
Site 71
S1027
N
G
Q
L
T
V
V
S
V
R
R
K
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation