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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AIM1L
Full Name:
Absent in melanoma 1-like protein
Alias:
Absent in melanoma 1-like; Aim1l; Beta/gamma crystallin domain-containing protein 2; Beta-gamma crystallin domain containing 2; Crybg2; FLJ38020
Type:
Mass (Da):
68650
Number AA:
UniProt ID:
Q8N1P7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
E
L
R
T
P
G
T
K
W
S
P
Q
G
I
Site 2
S11
R
T
P
G
T
K
W
S
P
Q
G
I
G
S
L
Site 3
S17
W
S
P
Q
G
I
G
S
L
R
R
V
V
W
D
Site 4
Y25
L
R
R
V
V
W
D
Y
S
T
P
E
I
S
L
Site 5
S26
R
R
V
V
W
D
Y
S
T
P
E
I
S
L
F
Site 6
T27
R
V
V
W
D
Y
S
T
P
E
I
S
L
F
S
Site 7
S31
D
Y
S
T
P
E
I
S
L
F
S
E
E
G
L
Site 8
T46
K
G
E
Q
V
K
L
T
E
A
L
K
N
S
Q
Site 9
T82
P
K
P
L
F
E
D
T
P
Y
I
L
E
P
G
Site 10
Y84
P
L
F
E
D
T
P
Y
I
L
E
P
G
E
Y
Site 11
Y91
Y
I
L
E
P
G
E
Y
P
T
S
E
A
W
G
Site 12
S94
E
P
G
E
Y
P
T
S
E
A
W
G
T
S
D
Site 13
T99
P
T
S
E
A
W
G
T
S
D
P
S
V
G
S
Site 14
S100
T
S
E
A
W
G
T
S
D
P
S
V
G
S
L
Site 15
S103
A
W
G
T
S
D
P
S
V
G
S
L
K
P
M
Site 16
S106
T
S
D
P
S
V
G
S
L
K
P
M
R
L
G
Site 17
S116
P
M
R
L
G
C
P
S
V
E
K
P
G
E
P
Site 18
Y128
G
E
P
R
A
V
V
Y
E
A
P
G
F
Q
G
Site 19
S137
A
P
G
F
Q
G
R
S
W
E
V
S
R
D
I
Site 20
S141
Q
G
R
S
W
E
V
S
R
D
I
Y
N
L
Q
Site 21
Y145
W
E
V
S
R
D
I
Y
N
L
Q
Q
P
E
D
Site 22
S153
N
L
Q
Q
P
E
D
S
Q
S
P
H
L
A
S
Site 23
S155
Q
Q
P
E
D
S
Q
S
P
H
L
A
S
V
G
Site 24
Y174
L
G
G
C
W
V
G
Y
E
K
E
G
F
R
G
Site 25
Y184
E
G
F
R
G
H
Q
Y
L
L
E
E
G
E
Y
Site 26
Y191
Y
L
L
E
E
G
E
Y
P
D
W
S
H
W
G
Site 27
T205
G
G
Y
D
E
L
L
T
S
L
R
V
I
R
T
Site 28
S206
G
Y
D
E
L
L
T
S
L
R
V
I
R
T
D
Site 29
T212
T
S
L
R
V
I
R
T
D
F
G
D
P
A
V
Site 30
Y273
V
G
F
S
G
E
Q
Y
V
L
E
K
G
V
Y
Site 31
Y280
Y
V
L
E
K
G
V
Y
R
N
C
E
D
W
G
Site 32
S291
E
D
W
G
A
G
N
S
T
L
A
S
L
Q
P
Site 33
S311
E
H
D
L
H
F
V
S
K
I
Q
L
F
S
R
Site 34
S317
V
S
K
I
Q
L
F
S
R
P
D
F
L
G
D
Site 35
S327
D
F
L
G
D
H
F
S
F
E
D
D
Q
A
A
Site 36
S338
D
Q
A
A
L
P
A
S
F
R
P
Q
S
C
R
Site 37
S343
P
A
S
F
R
P
Q
S
C
R
V
H
G
G
S
Site 38
S350
S
C
R
V
H
G
G
S
W
I
L
F
D
E
T
Site 39
S367
E
G
D
Q
H
I
L
S
E
G
E
F
P
T
L
Site 40
S392
L
G
S
L
Q
K
V
S
L
H
F
S
E
P
S
Site 41
S396
Q
K
V
S
L
H
F
S
E
P
S
I
F
L
Y
Site 42
S416
E
G
K
E
I
E
L
S
R
E
V
R
S
L
Q
Site 43
S433
G
F
N
N
H
V
L
S
V
R
I
K
G
G
I
Site 44
S468
I
T
N
W
L
T
Y
S
G
T
Q
R
V
G
S
Site 45
T470
N
W
L
T
Y
S
G
T
Q
R
V
G
S
L
Y
Site 46
S475
S
G
T
Q
R
V
G
S
L
Y
P
I
K
Q
R
Site 47
Y477
T
Q
R
V
G
S
L
Y
P
I
K
Q
R
R
V
Site 48
Y485
P
I
K
Q
R
R
V
Y
F
R
L
W
N
A
A
Site 49
Y525
A
G
G
S
C
I
W
Y
Y
E
D
G
L
L
K
Site 50
Y526
G
G
S
C
I
W
Y
Y
E
D
G
L
L
K
N
Site 51
S540
N
Q
M
A
P
T
M
S
L
Q
V
I
G
P
P
Site 52
T565
E
S
R
L
P
R
Q
T
W
S
I
S
E
S
G
Site 53
S567
R
L
P
R
Q
T
W
S
I
S
E
S
G
H
I
Site 54
S569
P
R
Q
T
W
S
I
S
E
S
G
H
I
C
S
Site 55
S576
S
E
S
G
H
I
C
S
Q
M
F
E
G
Q
I
Site 56
Y592
D
V
K
G
G
R
G
Y
D
R
D
H
V
V
L
Site 57
S608
E
P
D
E
D
R
A
S
Q
I
W
T
I
H
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation