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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NAGS
Full Name:
N-acetylglutamate synthase, mitochondrial
Alias:
AGAS; amino-acid acetyltransferase; ARGA; N-acetylglutamate synthase; NAT7
Type:
Amino Acid Metabolism - arginine and proline; Acetyltransferase; EC 2.3.1.1; Mitochondrial
Mass (Da):
58160
Number AA:
UniProt ID:
Q8N159
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0004042
GO:0003991
PhosphoSite+
KinaseNET
Biological Process:
GO:0006526
GO:0000050
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
R
L
R
G
R
G
G
T
G
G
A
R
R
L
S
Site 2
S32
T
G
G
A
R
R
L
S
C
G
A
R
R
R
A
Site 3
T43
R
R
R
A
A
R
G
T
S
P
G
R
R
L
S
Site 4
S44
R
R
A
A
R
G
T
S
P
G
R
R
L
S
T
Site 5
S50
T
S
P
G
R
R
L
S
T
A
W
S
Q
P
Q
Site 6
T51
S
P
G
R
R
L
S
T
A
W
S
Q
P
Q
P
Site 7
S54
R
R
L
S
T
A
W
S
Q
P
Q
P
P
P
E
Site 8
S70
Y
A
G
A
D
D
V
S
Q
S
P
V
A
E
E
Site 9
S72
G
A
D
D
V
S
Q
S
P
V
A
E
E
P
S
Site 10
S79
S
P
V
A
E
E
P
S
W
V
P
S
P
R
P
Site 11
S83
E
E
P
S
W
V
P
S
P
R
P
P
V
P
H
Site 12
S92
R
P
P
V
P
H
E
S
P
E
P
P
S
G
R
Site 13
S97
H
E
S
P
E
P
P
S
G
R
S
L
V
Q
R
Site 14
S100
P
E
P
P
S
G
R
S
L
V
Q
R
D
I
Q
Site 15
S116
F
L
N
Q
C
G
A
S
P
G
E
A
R
H
W
Site 16
S188
T
A
P
S
G
C
L
S
F
W
E
A
K
A
Q
Site 17
S269
G
E
T
A
A
R
R
S
V
L
L
D
S
L
E
Site 18
S280
D
S
L
E
V
T
A
S
L
A
K
A
L
R
P
Site 19
S302
N
T
G
G
L
R
D
S
S
H
K
V
L
S
N
Site 20
S303
T
G
G
L
R
D
S
S
H
K
V
L
S
N
V
Site 21
S308
D
S
S
H
K
V
L
S
N
V
N
L
P
A
D
Site 22
S341
R
L
I
V
D
V
L
S
R
L
P
H
H
S
S
Site 23
S348
S
R
L
P
H
H
S
S
A
V
I
T
A
A
S
Site 24
T356
A
V
I
T
A
A
S
T
L
L
T
E
L
F
S
Site 25
S367
E
L
F
S
N
K
G
S
G
T
L
F
K
N
A
Site 26
S382
E
R
M
L
R
V
R
S
L
D
K
L
D
Q
G
Site 27
S398
L
V
D
L
V
N
A
S
F
G
K
K
L
R
D
Site 28
Y407
G
K
K
L
R
D
D
Y
L
A
S
L
R
P
R
Site 29
S410
L
R
D
D
Y
L
A
S
L
R
P
R
L
H
S
Site 30
S417
S
L
R
P
R
L
H
S
I
Y
V
S
E
G
Y
Site 31
Y419
R
P
R
L
H
S
I
Y
V
S
E
G
Y
N
A
Site 32
S421
R
L
H
S
I
Y
V
S
E
G
Y
N
A
A
A
Site 33
Y424
S
I
Y
V
S
E
G
Y
N
A
A
A
I
L
T
Site 34
S448
Y
L
D
K
F
V
V
S
S
S
R
Q
G
Q
G
Site 35
S449
L
D
K
F
V
V
S
S
S
R
Q
G
Q
G
S
Site 36
S450
D
K
F
V
V
S
S
S
R
Q
G
Q
G
S
G
Site 37
S456
S
S
R
Q
G
Q
G
S
G
Q
M
L
W
E
C
Site 38
T470
C
L
R
R
D
L
Q
T
L
F
W
R
S
R
V
Site 39
Y485
T
N
P
I
N
P
W
Y
F
K
H
S
D
G
S
Site 40
S511
G
L
A
D
I
R
D
S
Y
E
L
V
N
H
A
Site 41
Y512
L
A
D
I
R
D
S
Y
E
L
V
N
H
A
K
Site 42
S524
H
A
K
G
L
P
D
S
F
H
K
P
A
S
D
Site 43
S530
D
S
F
H
K
P
A
S
D
P
G
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation