KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LGI3
Full Name:
Leucine-rich repeat LGI family member 3
Alias:
LGI1-like protein 4;Leucine-rich glioma-inactivated protein 3
Type:
Mass (Da):
61704
Number AA:
548
UniProt ID:
Q8N145
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
F
C
L
M
L
Q
V
S
A
K
R
P
P
K
T
Site 2
T36
S
A
K
R
P
P
K
T
P
P
C
P
P
S
C
Site 3
S42
K
T
P
P
C
P
P
S
C
S
C
T
R
D
T
Site 4
S44
P
P
C
P
P
S
C
S
C
T
R
D
T
A
F
Site 5
Y116
T
G
L
S
H
L
Q
Y
L
F
I
E
N
N
D
Site 6
S171
D
L
D
L
R
G
N
S
L
N
C
D
C
K
V
Site 7
Y196
N
T
T
V
A
P
I
Y
C
A
S
P
P
R
F
Site 8
S199
V
A
P
I
Y
C
A
S
P
P
R
F
Q
E
H
Site 9
Y264
C
T
I
L
K
W
D
Y
V
E
R
Q
L
R
D
Site 10
Y272
V
E
R
Q
L
R
D
Y
D
R
I
P
A
P
S
Site 11
Y304
A
Q
L
F
G
G
S
Y
I
Y
H
W
D
P
N
Site 12
T316
D
P
N
T
T
R
F
T
R
L
Q
D
I
D
P
Site 13
Y342
F
R
I
D
G
D
W
Y
F
A
V
A
D
S
S
Site 14
S355
S
S
K
A
G
A
T
S
L
Y
R
W
H
Q
N
Site 15
Y357
K
A
G
A
T
S
L
Y
R
W
H
Q
N
G
F
Site 16
T377
L
H
P
W
H
R
D
T
D
L
E
F
V
D
G
Site 17
S393
G
K
P
R
L
I
V
S
S
S
S
Q
A
P
V
Site 18
Y402
S
S
Q
A
P
V
I
Y
Q
W
S
R
T
Q
K
Site 19
S435
H
F
R
A
G
R
D
S
Y
L
C
L
S
R
Y
Site 20
Y436
F
R
A
G
R
D
S
Y
L
C
L
S
R
Y
I
Site 21
S440
R
D
S
Y
L
C
L
S
R
Y
I
G
D
S
K
Site 22
S446
L
S
R
Y
I
G
D
S
K
I
L
R
W
E
G
Site 23
S457
R
W
E
G
T
R
F
S
E
V
Q
A
L
P
S
Site 24
S464
S
E
V
Q
A
L
P
S
R
G
S
L
A
L
Q
Site 25
S485
R
R
Y
L
A
L
G
S
D
F
S
F
T
Q
I
Site 26
Y493
D
F
S
F
T
Q
I
Y
Q
W
D
E
G
R
Q
Site 27
Y518
Q
A
P
R
A
F
C
Y
M
P
A
G
D
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation