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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNTROB
Full Name:
Centrobin
Alias:
Centrobin; LYST-interacting protein 8
Type:
Cell cycle regulation
Mass (Da):
101253
Number AA:
903
UniProt ID:
Q8N137
International Prot ID:
IPI00295638
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005814
Uniprot
OncoNet
Molecular Function:
GO:0019904
PhosphoSite+
KinaseNET
Biological Process:
GO:0007099
GO:0051299
GO:0000910
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
T
S
A
D
S
P
S
S
P
L
G
A
Site 2
S9
A
T
S
A
D
S
P
S
S
P
L
G
A
E
D
Site 3
S10
T
S
A
D
S
P
S
S
P
L
G
A
E
D
L
Site 4
S19
L
G
A
E
D
L
L
S
D
S
S
E
P
P
G
Site 5
S21
A
E
D
L
L
S
D
S
S
E
P
P
G
L
N
Site 6
S22
E
D
L
L
S
D
S
S
E
P
P
G
L
N
Q
Site 7
S31
P
P
G
L
N
Q
V
S
S
E
V
T
S
Q
L
Site 8
S32
P
G
L
N
Q
V
S
S
E
V
T
S
Q
L
Y
Site 9
S36
Q
V
S
S
E
V
T
S
Q
L
Y
A
S
L
R
Site 10
Y39
S
E
V
T
S
Q
L
Y
A
S
L
R
L
S
R
Site 11
S41
V
T
S
Q
L
Y
A
S
L
R
L
S
R
Q
A
Site 12
S45
L
Y
A
S
L
R
L
S
R
Q
A
E
A
T
A
Site 13
T51
L
S
R
Q
A
E
A
T
A
R
A
Q
L
Y
L
Site 14
Y57
A
T
A
R
A
Q
L
Y
L
P
S
T
S
P
P
Site 15
S60
R
A
Q
L
Y
L
P
S
T
S
P
P
H
E
G
Site 16
T61
A
Q
L
Y
L
P
S
T
S
P
P
H
E
G
L
Site 17
S62
Q
L
Y
L
P
S
T
S
P
P
H
E
G
L
D
Site 18
S76
D
G
F
A
Q
E
L
S
R
S
L
S
V
G
L
Site 19
S78
F
A
Q
E
L
S
R
S
L
S
V
G
L
E
K
Site 20
S80
Q
E
L
S
R
S
L
S
V
G
L
E
K
N
L
Site 21
S101
K
H
I
F
E
M
E
S
V
R
G
Q
L
Q
T
Site 22
T108
S
V
R
G
Q
L
Q
T
M
L
Q
T
S
R
D
Site 23
T116
M
L
Q
T
S
R
D
T
A
Y
R
D
P
L
I
Site 24
Y118
Q
T
S
R
D
T
A
Y
R
D
P
L
I
P
G
Site 25
S128
P
L
I
P
G
A
G
S
E
R
R
E
E
D
S
Site 26
S135
S
E
R
R
E
E
D
S
F
D
S
D
S
T
A
Site 27
S138
R
E
E
D
S
F
D
S
D
S
T
A
T
L
L
Site 28
S140
E
D
S
F
D
S
D
S
T
A
T
L
L
N
T
Site 29
S154
T
R
P
L
Q
D
L
S
P
S
S
S
A
Q
A
Site 30
S156
P
L
Q
D
L
S
P
S
S
S
A
Q
A
L
E
Site 31
S157
L
Q
D
L
S
P
S
S
S
A
Q
A
L
E
E
Site 32
S158
Q
D
L
S
P
S
S
S
A
Q
A
L
E
E
L
Site 33
Y169
L
E
E
L
F
P
R
Y
T
S
L
R
P
G
P
Site 34
T170
E
E
L
F
P
R
Y
T
S
L
R
P
G
P
P
Site 35
S171
E
L
F
P
R
Y
T
S
L
R
P
G
P
P
L
Site 36
S192
G
L
R
D
A
L
D
S
E
H
T
R
R
K
H
Site 37
T230
A
A
D
R
K
K
D
T
M
I
E
Q
L
D
K
Site 38
T254
N
R
H
E
A
E
R
T
E
V
L
R
G
L
Q
Site 39
S286
T
R
L
E
Q
S
L
S
E
A
M
E
A
L
N
Site 40
S298
A
L
N
R
E
Q
E
S
A
R
L
Q
Q
R
E
Site 41
T308
L
Q
Q
R
E
R
E
T
L
E
E
E
R
Q
A
Site 42
S343
A
A
R
A
G
Q
L
S
E
H
R
E
L
E
T
Site 43
T361
A
L
E
E
E
R
Q
T
W
A
Q
Q
E
H
Q
Site 44
S391
L
E
R
E
K
E
K
S
Q
R
E
A
Q
A
A
Site 45
S410
H
Q
L
A
L
V
Q
S
E
V
R
R
L
E
G
Site 46
T421
R
L
E
G
E
L
D
T
A
R
R
E
R
D
A
Site 47
S434
D
A
L
Q
L
E
M
S
L
V
Q
A
R
Y
E
Site 48
Y440
M
S
L
V
Q
A
R
Y
E
S
Q
R
I
Q
L
Site 49
S442
L
V
Q
A
R
Y
E
S
Q
R
I
Q
L
E
S
Site 50
S449
S
Q
R
I
Q
L
E
S
E
L
A
V
Q
L
E
Site 51
T460
V
Q
L
E
Q
R
V
T
E
R
L
A
Q
A
Q
Site 52
S470
L
A
Q
A
Q
E
S
S
L
R
Q
A
A
S
L
Site 53
S476
S
S
L
R
Q
A
A
S
L
R
E
H
H
R
K
Site 54
Y521
Q
Q
Q
V
A
E
D
Y
E
L
R
L
A
R
E
Site 55
S569
D
E
A
N
Q
L
L
S
T
T
L
P
P
P
N
Site 56
T570
E
A
N
Q
L
L
S
T
T
L
P
P
P
N
P
Site 57
T571
A
N
Q
L
L
S
T
T
L
P
P
P
N
P
P
Site 58
S586
A
P
P
A
G
P
S
S
P
G
P
Q
E
P
E
Site 59
T601
K
E
E
R
R
V
W
T
M
P
P
M
A
V
A
Site 60
S647
L
L
G
P
S
F
Q
S
Q
H
S
F
Q
P
L
Site 61
S650
P
S
F
Q
S
Q
H
S
F
Q
P
L
E
P
K
Site 62
T661
L
E
P
K
P
D
L
T
S
S
T
A
G
A
F
Site 63
S662
E
P
K
P
D
L
T
S
S
T
A
G
A
F
S
Site 64
S663
P
K
P
D
L
T
S
S
T
A
G
A
F
S
A
Site 65
S728
P
Q
N
N
E
N
P
S
V
D
L
L
P
P
K
Site 66
T740
P
P
K
S
G
P
L
T
V
P
S
W
E
E
A
Site 67
S743
S
G
P
L
T
V
P
S
W
E
E
A
P
Q
V
Site 68
S778
F
R
V
P
E
P
P
S
S
H
S
Q
G
S
G
Site 69
S779
R
V
P
E
P
P
S
S
H
S
Q
G
S
G
P
Site 70
S781
P
E
P
P
S
S
H
S
Q
G
S
G
P
S
S
Site 71
S784
P
S
S
H
S
Q
G
S
G
P
S
S
G
S
P
Site 72
S787
H
S
Q
G
S
G
P
S
S
G
S
P
E
R
G
Site 73
S788
S
Q
G
S
G
P
S
S
G
S
P
E
R
G
G
Site 74
S790
G
S
G
P
S
S
G
S
P
E
R
G
G
D
G
Site 75
T799
E
R
G
G
D
G
L
T
F
P
R
Q
L
M
E
Site 76
S808
P
R
Q
L
M
E
V
S
Q
L
L
R
L
Y
Q
Site 77
Y814
V
S
Q
L
L
R
L
Y
Q
A
R
G
W
G
A
Site 78
Y830
P
A
E
D
L
L
L
Y
L
K
R
L
E
H
S
Site 79
S837
Y
L
K
R
L
E
H
S
G
T
D
G
R
G
D
Site 80
T839
K
R
L
E
H
S
G
T
D
G
R
G
D
N
V
Site 81
T851
D
N
V
P
R
R
N
T
D
S
R
L
G
E
I
Site 82
S853
V
P
R
R
N
T
D
S
R
L
G
E
I
P
R
Site 83
S865
I
P
R
K
E
I
P
S
Q
A
V
P
R
R
L
Site 84
T874
A
V
P
R
R
L
A
T
A
P
K
T
E
K
P
Site 85
T878
R
L
A
T
A
P
K
T
E
K
P
P
A
R
K
Site 86
S887
K
P
P
A
R
K
K
S
G
H
P
A
P
S
S
Site 87
S893
K
S
G
H
P
A
P
S
S
M
R
S
R
G
G
Site 88
S894
S
G
H
P
A
P
S
S
M
R
S
R
G
G
V
Site 89
S897
P
A
P
S
S
M
R
S
R
G
G
V
W
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation