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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP4X1
Full Name:
Cytochrome P450 4X1
Alias:
CYPIVX1
Type:
Mass (Da):
58875
Number AA:
509
UniProt ID:
Q8N118
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y76
L
E
E
I
I
E
K
Y
P
R
A
F
P
F
W
Site 2
Y98
F
C
I
Y
D
P
D
Y
A
K
T
L
L
S
R
Site 3
T101
Y
D
P
D
Y
A
K
T
L
L
S
R
T
D
P
Site 4
S104
D
Y
A
K
T
L
L
S
R
T
D
P
K
S
Q
Site 5
T106
A
K
T
L
L
S
R
T
D
P
K
S
Q
Y
L
Site 6
S110
L
S
R
T
D
P
K
S
Q
Y
L
Q
K
F
S
Site 7
Y112
R
T
D
P
K
S
Q
Y
L
Q
K
F
S
P
P
Site 8
S117
S
Q
Y
L
Q
K
F
S
P
P
L
L
G
K
G
Site 9
T141
F
Q
H
R
R
L
L
T
P
G
F
H
F
N
I
Site 10
S172
D
K
W
E
K
I
C
S
T
Q
D
T
S
V
E
Site 11
T173
K
W
E
K
I
C
S
T
Q
D
T
S
V
E
V
Site 12
T176
K
I
C
S
T
Q
D
T
S
V
E
V
Y
E
H
Site 13
Y181
Q
D
T
S
V
E
V
Y
E
H
I
N
S
M
S
Site 14
Y212
T
N
S
T
H
D
P
Y
A
K
A
I
F
E
L
Site 15
Y228
K
I
I
F
H
R
L
Y
S
L
L
Y
H
S
D
Site 16
Y232
H
R
L
Y
S
L
L
Y
H
S
D
I
I
F
K
Site 17
S241
S
D
I
I
F
K
L
S
P
Q
G
Y
R
F
Q
Site 18
Y245
F
K
L
S
P
Q
G
Y
R
F
Q
K
L
S
R
Site 19
S251
G
Y
R
F
Q
K
L
S
R
V
L
N
Q
Y
T
Site 20
Y257
L
S
R
V
L
N
Q
Y
T
D
T
I
I
Q
E
Site 21
S268
I
I
Q
E
R
K
K
S
L
Q
A
G
V
K
Q
Site 22
T278
A
G
V
K
Q
D
N
T
P
K
R
K
Y
Q
D
Site 23
Y283
D
N
T
P
K
R
K
Y
Q
D
F
L
D
I
V
Site 24
S292
D
F
L
D
I
V
L
S
A
K
D
E
S
G
S
Site 25
S297
V
L
S
A
K
D
E
S
G
S
S
F
S
D
I
Site 26
S300
A
K
D
E
S
G
S
S
F
S
D
I
D
V
H
Site 27
S302
D
E
S
G
S
S
F
S
D
I
D
V
H
S
E
Site 28
T312
D
V
H
S
E
V
S
T
F
L
L
A
G
H
D
Site 29
S354
R
G
I
L
G
D
G
S
S
I
T
W
D
Q
L
Site 30
S355
G
I
L
G
D
G
S
S
I
T
W
D
Q
L
G
Site 31
T357
L
G
D
G
S
S
I
T
W
D
Q
L
G
E
M
Site 32
T367
Q
L
G
E
M
S
Y
T
T
M
C
I
K
E
T
Site 33
S383
R
L
I
P
A
V
P
S
I
S
R
D
L
S
K
Site 34
S389
P
S
I
S
R
D
L
S
K
P
L
T
F
P
D
Site 35
T393
R
D
L
S
K
P
L
T
F
P
D
G
C
T
L
Site 36
S432
V
F
D
P
L
R
F
S
Q
E
N
S
D
Q
R
Site 37
S436
L
R
F
S
Q
E
N
S
D
Q
R
H
P
Y
A
Site 38
Y442
N
S
D
Q
R
H
P
Y
A
Y
L
P
F
S
A
Site 39
Y444
D
Q
R
H
P
Y
A
Y
L
P
F
S
A
G
S
Site 40
S448
P
Y
A
Y
L
P
F
S
A
G
S
R
N
C
I
Site 41
T486
P
D
P
T
R
P
L
T
F
P
N
H
F
I
L
Site 42
Y500
L
K
P
K
N
G
M
Y
L
H
L
K
K
L
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation