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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC52
Full Name:
Spindle and centriole-associated protein 1
Alias:
Coiled-coil domain-containing protein 52;Spindle and centriole-associated protein
Type:
Mass (Da):
96264
Number AA:
855
UniProt ID:
Q8N0Z3
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
P
R
V
G
V
R
K
T
P
K
V
K
K
K
K
Site 2
T26
P
K
V
K
K
K
K
T
S
V
K
Q
E
W
D
Site 3
S27
K
V
K
K
K
K
T
S
V
K
Q
E
W
D
N
Site 4
T35
V
K
Q
E
W
D
N
T
V
T
D
L
T
V
H
Site 5
T40
D
N
T
V
T
D
L
T
V
H
R
A
T
P
E
Site 6
T45
D
L
T
V
H
R
A
T
P
E
D
L
V
R
R
Site 7
S58
R
R
H
E
I
H
K
S
K
N
R
A
L
V
H
Site 8
S93
N
L
E
K
R
R
L
S
I
M
K
E
I
L
S
Site 9
Y103
K
E
I
L
S
D
Q
Y
Q
M
Q
D
V
L
E
Site 10
T128
E
L
F
P
R
R
R
T
G
F
P
N
V
T
V
Site 11
T134
R
T
G
F
P
N
V
T
V
A
P
D
S
S
Q
Site 12
T152
V
V
N
Q
D
P
I
T
Q
S
I
F
N
E
S
Site 13
S154
N
Q
D
P
I
T
Q
S
I
F
N
E
S
V
I
Site 14
T176
V
D
G
E
E
E
G
T
V
N
S
Q
S
G
E
Site 15
S179
E
E
E
G
T
V
N
S
Q
S
G
E
S
E
N
Site 16
S181
E
G
T
V
N
S
Q
S
G
E
S
E
N
E
N
Site 17
S193
N
E
N
E
L
D
N
S
L
N
S
Q
S
N
T
Site 18
S196
E
L
D
N
S
L
N
S
Q
S
N
T
N
T
D
Site 19
S198
D
N
S
L
N
S
Q
S
N
T
N
T
D
R
F
Site 20
T200
S
L
N
S
Q
S
N
T
N
T
D
R
F
L
Q
Site 21
T202
N
S
Q
S
N
T
N
T
D
R
F
L
Q
Q
L
Site 22
T222
E
L
I
S
K
L
W
T
D
I
Q
Q
K
I
A
Site 23
S232
Q
Q
K
I
A
T
Q
S
Q
I
T
P
P
G
T
Site 24
T235
I
A
T
Q
S
Q
I
T
P
P
G
T
P
S
S
Site 25
T239
S
Q
I
T
P
P
G
T
P
S
S
A
L
S
S
Site 26
S241
I
T
P
P
G
T
P
S
S
A
L
S
S
G
E
Site 27
S242
T
P
P
G
T
P
S
S
A
L
S
S
G
E
Q
Site 28
S245
G
T
P
S
S
A
L
S
S
G
E
Q
R
A
A
Site 29
S246
T
P
S
S
A
L
S
S
G
E
Q
R
A
A
L
Site 30
T264
N
A
V
K
R
L
Q
T
R
L
Q
P
E
E
S
Site 31
S271
T
R
L
Q
P
E
E
S
T
E
T
L
D
S
S
Site 32
T274
Q
P
E
E
S
T
E
T
L
D
S
S
Y
V
V
Site 33
S277
E
S
T
E
T
L
D
S
S
Y
V
V
G
H
V
Site 34
Y279
T
E
T
L
D
S
S
Y
V
V
G
H
V
L
N
Site 35
S307
K
P
N
L
H
A
L
S
K
P
K
K
N
I
S
Site 36
S314
S
K
P
K
K
N
I
S
S
G
S
T
T
S
A
Site 37
S317
K
K
N
I
S
S
G
S
T
T
S
A
D
L
P
Site 38
T318
K
N
I
S
S
G
S
T
T
S
A
D
L
P
N
Site 39
T319
N
I
S
S
G
S
T
T
S
A
D
L
P
N
R
Site 40
S320
I
S
S
G
S
T
T
S
A
D
L
P
N
R
T
Site 41
S329
D
L
P
N
R
T
N
S
N
L
D
V
L
K
H
Site 42
Y348
V
E
H
E
M
E
E
Y
E
R
W
T
G
R
E
Site 43
T352
M
E
E
Y
E
R
W
T
G
R
E
V
K
G
L
Site 44
S361
R
E
V
K
G
L
Q
S
S
Q
G
L
T
G
F
Site 45
S362
E
V
K
G
L
Q
S
S
Q
G
L
T
G
F
T
Site 46
Y382
S
L
C
R
L
V
R
Y
L
K
E
S
E
I
Q
Site 47
S386
L
V
R
Y
L
K
E
S
E
I
Q
L
R
K
E
Site 48
T428
L
R
E
E
N
A
A
T
Q
A
R
L
Q
Q
Y
Site 49
S445
T
T
D
E
Q
L
I
S
L
T
H
A
I
K
N
Site 50
S465
N
R
Q
E
I
Q
A
S
E
S
G
A
T
G
R
Site 51
T470
Q
A
S
E
S
G
A
T
G
R
R
V
M
D
S
Site 52
S477
T
G
R
R
V
M
D
S
P
E
R
P
V
V
N
Site 53
S510
E
E
L
P
V
K
L
S
Q
V
P
D
P
P
D
Site 54
T537
F
E
P
A
V
L
L
T
P
P
R
Q
K
S
N
Site 55
S543
L
T
P
P
R
Q
K
S
N
L
K
F
S
P
L
Site 56
S548
Q
K
S
N
L
K
F
S
P
L
Q
D
V
L
R
Site 57
T557
L
Q
D
V
L
R
R
T
V
Q
T
R
P
A
P
Site 58
T569
P
A
P
R
L
P
P
T
V
E
I
I
E
K
E
Site 59
T588
E
K
T
L
P
I
D
T
D
I
Q
N
S
S
E
Site 60
T601
S
E
E
N
R
L
F
T
Q
R
W
R
V
S
H
Site 61
T617
G
E
D
L
E
N
K
T
Q
A
P
F
V
N
L
Site 62
S625
Q
A
P
F
V
N
L
S
Q
P
L
C
N
S
H
Site 63
S631
L
S
Q
P
L
C
N
S
H
S
N
T
Q
Q
S
Site 64
S633
Q
P
L
C
N
S
H
S
N
T
Q
Q
S
R
S
Site 65
T635
L
C
N
S
H
S
N
T
Q
Q
S
R
S
P
T
Site 66
S638
S
H
S
N
T
Q
Q
S
R
S
P
T
F
S
E
Site 67
S640
S
N
T
Q
Q
S
R
S
P
T
F
S
E
E
L
Site 68
T642
T
Q
Q
S
R
S
P
T
F
S
E
E
L
P
V
Site 69
S644
Q
S
R
S
P
T
F
S
E
E
L
P
V
L
G
Site 70
S661
Q
Q
L
R
T
N
E
S
L
I
Q
R
K
D
I
Site 71
T670
I
Q
R
K
D
I
M
T
R
I
A
D
L
T
L
Site 72
T676
M
T
R
I
A
D
L
T
L
Q
N
S
A
I
K
Site 73
S680
A
D
L
T
L
Q
N
S
A
I
K
A
H
M
N
Site 74
S708
R
E
L
N
K
Q
E
S
A
S
D
M
T
S
T
Site 75
S710
L
N
K
Q
E
S
A
S
D
M
T
S
T
F
P
Site 76
S714
E
S
A
S
D
M
T
S
T
F
P
V
A
Q
S
Site 77
T715
S
A
S
D
M
T
S
T
F
P
V
A
Q
S
L
Site 78
S721
S
T
F
P
V
A
Q
S
L
T
P
G
S
M
E
Site 79
T723
F
P
V
A
Q
S
L
T
P
G
S
M
E
E
R
Site 80
S726
A
Q
S
L
T
P
G
S
M
E
E
R
I
A
E
Site 81
S738
I
A
E
L
N
R
Q
S
M
E
A
R
G
K
L
Site 82
S760
K
L
V
G
L
N
L
S
P
P
M
S
P
V
Q
Site 83
S764
L
N
L
S
P
P
M
S
P
V
Q
L
P
L
R
Site 84
T774
Q
L
P
L
R
A
W
T
E
G
A
K
R
T
I
Site 85
S784
A
K
R
T
I
E
V
S
I
P
G
A
E
A
P
Site 86
S793
P
G
A
E
A
P
E
S
S
K
C
S
T
V
S
Site 87
S794
G
A
E
A
P
E
S
S
K
C
S
T
V
S
P
Site 88
S797
A
P
E
S
S
K
C
S
T
V
S
P
V
S
G
Site 89
T798
P
E
S
S
K
C
S
T
V
S
P
V
S
G
I
Site 90
S800
S
S
K
C
S
T
V
S
P
V
S
G
I
N
T
Site 91
S803
C
S
T
V
S
P
V
S
G
I
N
T
R
R
S
Site 92
T807
S
P
V
S
G
I
N
T
R
R
S
S
G
A
T
Site 93
S810
S
G
I
N
T
R
R
S
S
G
A
T
G
N
S
Site 94
S811
G
I
N
T
R
R
S
S
G
A
T
G
N
S
C
Site 95
T814
T
R
R
S
S
G
A
T
G
N
S
C
S
P
L
Site 96
S817
S
S
G
A
T
G
N
S
C
S
P
L
N
A
T
Site 97
S819
G
A
T
G
N
S
C
S
P
L
N
A
T
S
G
Site 98
S825
C
S
P
L
N
A
T
S
G
S
G
R
F
T
P
Site 99
S827
P
L
N
A
T
S
G
S
G
R
F
T
P
L
N
Site 100
T831
T
S
G
S
G
R
F
T
P
L
N
P
R
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation