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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPG20
Full Name:
Spartin
Alias:
KIAA0610; Spastic paraplegia 20 (Troyer syndrome); Spastic paraplegia 20 protein; Spastic paraplegia 20, spartin; TAHCCP1; Trans-activated by hepatitis C virus core protein 1
Type:
Unknown function
Mass (Da):
72833
Number AA:
666
UniProt ID:
Q8N0X7
International Prot ID:
IPI00430622
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y45
Q
K
E
E
A
K
N
Y
Y
K
Q
G
I
G
H
Site 2
Y46
K
E
E
A
K
N
Y
Y
K
Q
G
I
G
H
L
Site 3
S58
G
H
L
L
R
G
I
S
I
S
S
K
E
S
E
Site 4
S60
L
L
R
G
I
S
I
S
S
K
E
S
E
H
T
Site 5
S61
L
R
G
I
S
I
S
S
K
E
S
E
H
T
G
Site 6
S64
I
S
I
S
S
K
E
S
E
H
T
G
P
G
W
Site 7
T67
S
S
K
E
S
E
H
T
G
P
G
W
E
S
A
Site 8
Y114
L
Q
E
V
P
K
L
Y
P
E
F
P
P
K
D
Site 9
S131
E
K
L
P
E
P
Q
S
F
S
S
A
P
Q
H
Site 10
S133
L
P
E
P
Q
S
F
S
S
A
P
Q
H
A
E
Site 11
T147
E
V
N
G
N
T
S
T
P
S
A
G
A
V
A
Site 12
S163
P
A
S
L
S
L
P
S
Q
S
C
P
A
E
A
Site 13
S165
S
L
S
L
P
S
Q
S
C
P
A
E
A
P
P
Site 14
T175
A
E
A
P
P
A
Y
T
P
Q
A
A
E
G
H
Site 15
Y183
P
Q
A
A
E
G
H
Y
T
V
S
Y
G
T
D
Site 16
T184
Q
A
A
E
G
H
Y
T
V
S
Y
G
T
D
S
Site 17
S186
A
E
G
H
Y
T
V
S
Y
G
T
D
S
G
E
Site 18
Y187
E
G
H
Y
T
V
S
Y
G
T
D
S
G
E
F
Site 19
S191
T
V
S
Y
G
T
D
S
G
E
F
S
S
V
G
Site 20
S195
G
T
D
S
G
E
F
S
S
V
G
E
E
F
Y
Site 21
S196
T
D
S
G
E
F
S
S
V
G
E
E
F
Y
R
Site 22
Y202
S
S
V
G
E
E
F
Y
R
N
H
S
Q
P
P
Site 23
S206
E
E
F
Y
R
N
H
S
Q
P
P
P
L
E
T
Site 24
S240
V
N
P
A
G
E
V
S
A
P
S
Y
P
G
Y
Site 25
S243
A
G
E
V
S
A
P
S
Y
P
G
Y
L
R
I
Site 26
T260
F
L
D
N
S
L
D
T
V
L
N
R
P
P
G
Site 27
Y276
L
Q
V
C
D
W
L
Y
P
L
V
P
D
R
S
Site 28
S283
Y
P
L
V
P
D
R
S
P
V
L
K
C
T
A
Site 29
S331
E
D
L
L
R
Q
M
S
D
L
R
L
Q
A
N
Site 30
S357
I
P
G
R
T
R
P
S
S
D
Q
L
K
E
A
Site 31
S358
P
G
R
T
R
P
S
S
D
Q
L
K
E
A
S
Site 32
S365
S
D
Q
L
K
E
A
S
G
T
D
V
K
Q
L
Site 33
T367
Q
L
K
E
A
S
G
T
D
V
K
Q
L
D
Q
Site 34
T392
R
G
K
R
A
K
D
T
S
S
E
E
V
N
L
Site 35
S393
G
K
R
A
K
D
T
S
S
E
E
V
N
L
S
Site 36
S394
K
R
A
K
D
T
S
S
E
E
V
N
L
S
H
Site 37
S400
S
S
E
E
V
N
L
S
H
I
V
P
C
E
P
Site 38
S420
P
K
E
L
P
E
W
S
E
K
V
A
H
N
I
Site 39
S454
K
A
I
Q
K
G
A
S
K
L
R
E
R
I
Q
Site 40
S470
E
E
K
P
V
E
V
S
P
A
V
T
K
G
L
Site 41
S524
G
S
K
L
V
P
E
S
L
K
K
D
K
D
G
Site 42
S533
K
K
D
K
D
G
K
S
P
L
D
G
A
M
V
Site 43
T551
S
S
V
Q
G
F
S
T
V
W
Q
G
L
E
C
Site 44
T574
V
S
A
E
T
V
Q
T
V
R
Y
K
Y
G
Y
Site 45
Y579
V
Q
T
V
R
Y
K
Y
G
Y
N
A
G
E
A
Site 46
Y581
T
V
R
Y
K
Y
G
Y
N
A
G
E
A
T
H
Site 47
Y628
G
H
T
L
L
E
D
Y
Q
I
V
D
N
S
Q
Site 48
S634
D
Y
Q
I
V
D
N
S
Q
R
E
N
Q
E
G
Site 49
T655
R
G
E
K
D
E
Q
T
K
E
V
K
E
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation