KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF654
Full Name:
Zinc finger protein 654
Alias:
FLJ10997; FLJ21142; IQM1; Melanoma-associated antigen; Purkinje cell protein 4 like 1; Zinc finger 654; ZN654
Type:
Mass (Da):
65824
Number AA:
581
UniProt ID:
Q8IZM8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S75
A
L
E
E
I
N
C
S
S
S
S
I
S
F
E
Site 2
S76
L
E
E
I
N
C
S
S
S
S
I
S
F
E
N
Site 3
S77
E
E
I
N
C
S
S
S
S
I
S
F
E
N
G
Site 4
S78
E
I
N
C
S
S
S
S
I
S
F
E
N
G
N
Site 5
S80
N
C
S
S
S
S
I
S
F
E
N
G
N
S
D
Site 6
S86
I
S
F
E
N
G
N
S
D
S
K
D
L
E
V
Site 7
S88
F
E
N
G
N
S
D
S
K
D
L
E
V
E
T
Site 8
T95
S
K
D
L
E
V
E
T
L
T
A
S
S
E
G
Site 9
T97
D
L
E
V
E
T
L
T
A
S
S
E
G
N
K
Site 10
S134
E
N
V
I
E
N
G
S
P
N
N
S
L
N
N
Site 11
S138
E
N
G
S
P
N
N
S
L
N
N
V
F
K
P
Site 12
T147
N
N
V
F
K
P
L
T
E
C
G
D
D
Y
E
Site 13
Y153
L
T
E
C
G
D
D
Y
E
E
E
E
D
E
E
Site 14
Y163
E
E
D
E
E
G
D
Y
E
E
D
D
Y
D
L
Site 15
Y168
G
D
Y
E
E
D
D
Y
D
L
N
Q
E
T
S
Site 16
Y191
V
C
H
P
K
D
I
Y
A
T
D
Q
E
G
N
Site 17
T222
F
L
N
K
H
A
M
T
V
H
P
T
D
L
N
Site 18
T233
T
D
L
N
V
R
Q
T
V
M
K
W
S
K
G
Site 19
Y264
D
H
L
N
R
H
S
Y
P
N
V
Y
F
C
L
Site 20
S291
Q
L
A
Q
H
T
K
S
H
R
T
F
Q
A
Q
Site 21
S300
R
T
F
Q
A
Q
C
S
F
P
E
C
H
E
L
Site 22
Y315
F
E
D
L
P
L
L
Y
E
H
E
A
Q
H
Y
Site 23
Y322
Y
E
H
E
A
Q
H
Y
L
S
K
T
P
E
S
Site 24
S324
H
E
A
Q
H
Y
L
S
K
T
P
E
S
S
A
Site 25
T326
A
Q
H
Y
L
S
K
T
P
E
S
S
A
Q
P
Site 26
S329
Y
L
S
K
T
P
E
S
S
A
Q
P
S
E
T
Site 27
S330
L
S
K
T
P
E
S
S
A
Q
P
S
E
T
I
Site 28
S334
P
E
S
S
A
Q
P
S
E
T
I
L
W
D
V
Site 29
T343
T
I
L
W
D
V
Q
T
D
S
N
P
N
Q
E
Site 30
S345
L
W
D
V
Q
T
D
S
N
P
N
Q
E
K
D
Site 31
S353
N
P
N
Q
E
K
D
S
S
S
N
E
K
Q
T
Site 32
S354
P
N
Q
E
K
D
S
S
S
N
E
K
Q
T
I
Site 33
S355
N
Q
E
K
D
S
S
S
N
E
K
Q
T
I
S
Site 34
S362
S
N
E
K
Q
T
I
S
L
P
V
S
T
S
K
Site 35
S366
Q
T
I
S
L
P
V
S
T
S
K
S
R
K
E
Site 36
S368
I
S
L
P
V
S
T
S
K
S
R
K
E
S
T
Site 37
S370
L
P
V
S
T
S
K
S
R
K
E
S
T
E
P
Site 38
S374
T
S
K
S
R
K
E
S
T
E
P
K
T
C
I
Site 39
T379
K
E
S
T
E
P
K
T
C
I
E
S
M
E
K
Site 40
S390
S
M
E
K
K
T
D
S
L
V
Q
N
G
N
E
Site 41
S399
V
Q
N
G
N
E
R
S
D
D
T
V
S
N
I
Site 42
T402
G
N
E
R
S
D
D
T
V
S
N
I
S
L
I
Site 43
S404
E
R
S
D
D
T
V
S
N
I
S
L
I
D
Q
Site 44
S407
D
D
T
V
S
N
I
S
L
I
D
Q
K
M
P
Site 45
S420
M
P
D
I
E
P
N
S
E
N
N
C
S
S
S
Site 46
S425
P
N
S
E
N
N
C
S
S
S
D
I
V
N
G
Site 47
S427
S
E
N
N
C
S
S
S
D
I
V
N
G
H
S
Site 48
T439
G
H
S
E
I
E
Q
T
P
L
V
S
S
D
P
Site 49
T452
D
P
A
L
K
I
D
T
N
R
I
R
T
E
N
Site 50
T457
I
D
T
N
R
I
R
T
E
N
G
S
I
L
P
Site 51
S461
R
I
R
T
E
N
G
S
I
L
P
S
V
V
P
Site 52
S465
E
N
G
S
I
L
P
S
V
V
P
Q
E
H
N
Site 53
T473
V
V
P
Q
E
H
N
T
L
P
V
S
Q
A
P
Site 54
S477
E
H
N
T
L
P
V
S
Q
A
P
S
K
P
N
Site 55
S481
L
P
V
S
Q
A
P
S
K
P
N
L
T
S
E
Site 56
T486
A
P
S
K
P
N
L
T
S
E
H
T
S
Y
G
Site 57
S487
P
S
K
P
N
L
T
S
E
H
T
S
Y
G
L
Site 58
S491
N
L
T
S
E
H
T
S
Y
G
L
I
L
T
K
Site 59
Y492
L
T
S
E
H
T
S
Y
G
L
I
L
T
K
P
Site 60
S507
Y
V
R
P
L
P
P
S
Y
L
D
E
R
Y
L
Site 61
Y508
V
R
P
L
P
P
S
Y
L
D
E
R
Y
L
S
Site 62
Y513
P
S
Y
L
D
E
R
Y
L
S
M
P
K
R
R
Site 63
S515
Y
L
D
E
R
Y
L
S
M
P
K
R
R
K
F
Site 64
T524
P
K
R
R
K
F
L
T
D
R
V
D
A
C
S
Site 65
S531
T
D
R
V
D
A
C
S
D
Q
D
N
V
Y
K
Site 66
Y537
C
S
D
Q
D
N
V
Y
K
K
S
V
K
R
L
Site 67
S540
Q
D
N
V
Y
K
K
S
V
K
R
L
R
C
G
Site 68
T570
L
A
Q
K
K
C
Q
T
L
F
G
F
D
S
D
Site 69
S576
Q
T
L
F
G
F
D
S
D
D
E
S
A
_
_
Site 70
S580
G
F
D
S
D
D
E
S
A
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation