PhosphoNET

           
Protein Info 
   
Short Name:  MAML2
Full Name:  Mastermind-like protein 2
Alias:  KIAA1819; MAM2; Mam-2; MAM3; MAM-3; Mastermind-like 2; Mastermind-like 2 (Drosophila)
Type:  Transcription, coactivator/corepressor
Mass (Da):  124812
Number AA:  1153
UniProt ID:  Q8IZL2
International Prot ID:  IPI00064200
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016607     Uniprot OncoNet
Molecular Function:  GO:0003713     PhosphoSite+ KinaseNET
Biological Process:  GO:0007219  GO:0045944  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S34SVTPRVHSAIVERLR
Site 2S65YERGRAESSDRERES
Site 3S66ERGRAESSDREREST
Site 4S72SSDRERESTLQLLSL
Site 5T73SDRERESTLQLLSLV
Site 6S78ESTLQLLSLVQHGQG
Site 7S141HQQHLLNSSNNGGSG
Site 8S142QQHLLNSSNNGGSGG
Site 9S159GEQQPPASTPGDQRN
Site 10T160EQQPPASTPGDQRNS
Site 11S167TPGDQRNSALIALQG
Site 12S185RKQVVNLSPANSKRP
Site 13S189VNLSPANSKRPNGFV
Site 14S199PNGFVDNSFLDIKRI
Site 15S213IRVGENLSAGQGGLQ
Site 16S226LQINNGQSQIMSGTL
Site 17S230NGQSQIMSGTLPMSQ
Site 18T232QSQIMSGTLPMSQAP
Site 19S236MSGTLPMSQAPLRKT
Site 20T243SQAPLRKTNTLPSHT
Site 21T245APLRKTNTLPSHTHS
Site 22S248RKTNTLPSHTHSPGN
Site 23T250TNTLPSHTHSPGNGL
Site 24S252TLPSHTHSPGNGLFN
Site 25T272VKKEPGETLSCSKHM
Site 26S274KEPGETLSCSKHMDG
Site 27S276PGETLSCSKHMDGQM
Site 28Y293ENIFPNRYGDDPGEQ
Site 29T314QELFNELTNISVPPM
Site 30S317FNELTNISVPPMSDL
Site 31S322NISVPPMSDLELENM
Site 32S348NIDLGQQSQRSTPRP
Site 33S351LGQQSQRSTPRPSLP
Site 34T352GQQSQRSTPRPSLPM
Site 35S356QRSTPRPSLPMEKIV
Site 36S369IVIKSEYSPGLTQGP
Site 37T373SEYSPGLTQGPSGSP
Site 38S377PGLTQGPSGSPQLRP
Site 39S379LTQGPSGSPQLRPPS
Site 40S386SPQLRPPSAGPAFSM
Site 41S396PAFSMANSALSTSSP
Site 42S399SMANSALSTSSPIPS
Site 43S402NSALSTSSPIPSVPQ
Site 44S406STSSPIPSVPQSQAQ
Site 45S410PIPSVPQSQAQPQTG
Site 46T416QSQAQPQTGSGASRA
Site 47S426GASRALPSWQEVSHA
Site 48S462QHQPTNWSALPSSAG
Site 49S466TNWSALPSSAGPSPG
Site 50S467NWSALPSSAGPSPGP
Site 51S471LPSSAGPSPGPFGQE
Site 52S482FGQEKIPSPSFGQQT
Site 53S484QEKIPSPSFGQQTFS
Site 54T489SPSFGQQTFSPQSSP
Site 55S491SFGQQTFSPQSSPMP
Site 56S494QQTFSPQSSPMPGVA
Site 57S495QTFSPQSSPMPGVAG
Site 58Y513QSKVMANYMYKAGPS
Site 59Y515KVMANYMYKAGPSAQ
Site 60S538QQKPQDLSRSFINNP
Site 61S540KPQDLSRSFINNPHP
Site 62S573QANQQMPSVLPSQNK
Site 63S577QMPSVLPSQNKPSLL
Site 64Y586NKPSLLHYTQQQQQQ
Site 65S673QPAQSLPSQPLLRSP
Site 66S744GYMNSQQSLLNQQLM
Site 67S818TAQYSGGSSTISLNS
Site 68S822SGGSSTISLNSNQAL
Site 69S825SSTISLNSNQALANP
Site 70S847TPNSSLLSTSHGTRM
Site 71T958NVMITSNTTAPNWAS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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