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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNC5B
Full Name:
Netrin receptor UNC5B
Alias:
Netrin receptor UNC5B; P53RDL1; P53-regulated receptor for death and life protein 1; Protein unc-5 homolog B; Unc-5 B; Unc-5 homolog 2; Unc-5 homolog B; UNC5H2
Type:
Receptor, misc.
Mass (Da):
103619
Number AA:
945
UniProt ID:
Q8IZJ1
International Prot ID:
IPI00328431
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
L
C
W
D
P
R
L
S
Q
A
G
T
D
S
G
Site 2
T341
G
G
R
D
C
S
G
T
L
L
D
S
K
N
C
Site 3
T408
R
N
C
R
D
F
D
T
D
I
T
D
S
S
A
Site 4
T411
R
D
F
D
T
D
I
T
D
S
S
A
A
L
T
Site 5
S413
F
D
T
D
I
T
D
S
S
A
A
L
T
G
G
Site 6
S414
D
T
D
I
T
D
S
S
A
A
L
T
G
G
F
Site 7
T418
T
D
S
S
A
A
L
T
G
G
F
H
P
V
N
Site 8
T428
F
H
P
V
N
F
K
T
A
R
P
S
N
P
Q
Site 9
S432
N
F
K
T
A
R
P
S
N
P
Q
L
L
H
P
Site 10
S440
N
P
Q
L
L
H
P
S
V
P
P
D
L
T
A
Site 11
T446
P
S
V
P
P
D
L
T
A
S
A
G
I
Y
R
Site 12
Y457
G
I
Y
R
G
P
V
Y
A
L
Q
D
S
T
D
Site 13
S462
P
V
Y
A
L
Q
D
S
T
D
K
I
P
M
T
Site 14
T469
S
T
D
K
I
P
M
T
N
S
P
L
L
D
P
Site 15
S471
D
K
I
P
M
T
N
S
P
L
L
D
P
L
P
Site 16
Y485
P
S
L
K
V
K
V
Y
S
S
S
T
T
G
S
Site 17
S486
S
L
K
V
K
V
Y
S
S
S
T
T
G
S
G
Site 18
S487
L
K
V
K
V
Y
S
S
S
T
T
G
S
G
P
Site 19
S488
K
V
K
V
Y
S
S
S
T
T
G
S
G
P
G
Site 20
T490
K
V
Y
S
S
S
T
T
G
S
G
P
G
L
A
Site 21
S492
Y
S
S
S
T
T
G
S
G
P
G
L
A
D
G
Site 22
T510
L
G
V
L
P
P
G
T
Y
P
S
D
F
A
R
Site 23
Y511
G
V
L
P
P
G
T
Y
P
S
D
F
A
R
D
Site 24
S513
L
P
P
G
T
Y
P
S
D
F
A
R
D
T
H
Site 25
T519
P
S
D
F
A
R
D
T
H
F
L
H
L
R
S
Site 26
S526
T
H
F
L
H
L
R
S
A
S
L
G
S
Q
Q
Site 27
S528
F
L
H
L
R
S
A
S
L
G
S
Q
Q
L
L
Site 28
S531
L
R
S
A
S
L
G
S
Q
Q
L
L
G
L
P
Site 29
S543
G
L
P
R
D
P
G
S
S
V
S
G
T
F
G
Site 30
S544
L
P
R
D
P
G
S
S
V
S
G
T
F
G
C
Site 31
S546
R
D
P
G
S
S
V
S
G
T
F
G
C
L
G
Site 32
T548
P
G
S
S
V
S
G
T
F
G
C
L
G
G
R
Site 33
Y581
Q
G
K
F
Y
E
M
Y
L
L
I
N
K
A
E
Site 34
T590
L
I
N
K
A
E
S
T
L
P
L
S
E
G
T
Site 35
S594
A
E
S
T
L
P
L
S
E
G
T
Q
T
V
L
Site 36
T599
P
L
S
E
G
T
Q
T
V
L
S
P
S
V
T
Site 37
S602
E
G
T
Q
T
V
L
S
P
S
V
T
C
G
P
Site 38
T651
G
H
W
E
E
V
V
T
L
D
E
E
T
L
N
Site 39
T659
L
D
E
E
T
L
N
T
P
C
Y
C
Q
L
E
Site 40
Y662
E
T
L
N
T
P
C
Y
C
Q
L
E
P
R
A
Site 41
S686
T
Y
V
F
T
G
E
S
Y
S
R
S
A
V
K
Site 42
S688
V
F
T
G
E
S
Y
S
R
S
A
V
K
R
L
Site 43
S690
T
G
E
S
Y
S
R
S
A
V
K
R
L
Q
L
Site 44
Y737
L
E
R
T
L
G
G
Y
L
V
E
E
P
K
P
Site 45
S750
K
P
L
M
F
K
D
S
Y
H
N
L
R
L
S
Site 46
Y751
P
L
M
F
K
D
S
Y
H
N
L
R
L
S
L
Site 47
S757
S
Y
H
N
L
R
L
S
L
H
D
L
P
H
A
Site 48
Y774
R
S
K
L
L
A
K
Y
Q
E
I
P
F
Y
H
Site 49
Y780
K
Y
Q
E
I
P
F
Y
H
I
W
S
G
S
Q
Site 50
T793
S
Q
K
A
L
H
C
T
F
T
L
E
R
H
S
Site 51
T795
K
A
L
H
C
T
F
T
L
E
R
H
S
L
A
Site 52
S800
T
F
T
L
E
R
H
S
L
A
S
T
E
L
T
Site 53
S803
L
E
R
H
S
L
A
S
T
E
L
T
C
K
I
Site 54
T804
E
R
H
S
L
A
S
T
E
L
T
C
K
I
C
Site 55
T831
L
H
T
T
L
A
E
T
P
A
G
S
L
D
T
Site 56
T838
T
P
A
G
S
L
D
T
L
C
S
A
P
G
S
Site 57
S869
I
R
Q
K
I
C
N
S
L
D
A
P
N
S
R
Site 58
S875
N
S
L
D
A
P
N
S
R
G
N
D
W
R
M
Site 59
S888
R
M
L
A
Q
K
L
S
M
D
R
Y
L
N
Y
Site 60
Y892
Q
K
L
S
M
D
R
Y
L
N
Y
F
A
T
K
Site 61
Y895
S
M
D
R
Y
L
N
Y
F
A
T
K
A
S
P
Site 62
T898
R
Y
L
N
Y
F
A
T
K
A
S
P
T
G
V
Site 63
S922
Q
D
D
G
D
L
N
S
L
A
S
A
L
E
E
Site 64
S925
G
D
L
N
S
L
A
S
A
L
E
E
M
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation