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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPUSD2
Full Name:
RNA pseudouridylate synthase domain-containing protein 2
Alias:
RUSD2
Type:
Mass (Da):
61311
Number AA:
545
UniProt ID:
Q8IZ73
International Prot ID:
IPI00150963
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0009982
PhosphoSite+
KinaseNET
Biological Process:
GO:0001522
GO:0006139
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
R
V
L
G
H
W
R
Y
D
L
R
R
P
S
F
Site 2
S23
R
Y
D
L
R
R
P
S
F
T
R
T
W
S
G
Site 3
T25
D
L
R
R
P
S
F
T
R
T
W
S
G
D
K
Site 4
T27
R
R
P
S
F
T
R
T
W
S
G
D
K
G
P
Site 5
S29
P
S
F
T
R
T
W
S
G
D
K
G
P
M
A
Site 6
T38
D
K
G
P
M
A
E
T
V
S
T
Q
V
G
T
Site 7
S40
G
P
M
A
E
T
V
S
T
Q
V
G
T
E
G
Site 8
T41
P
M
A
E
T
V
S
T
Q
V
G
T
E
G
G
Site 9
S52
T
E
G
G
L
R
A
S
H
Q
Q
N
G
D
A
Site 10
S68
G
D
A
K
V
E
L
S
P
G
P
P
K
P
A
Site 11
S90
P
V
G
G
E
H
P
S
A
A
A
P
G
P
G
Site 12
T106
H
K
K
R
R
G
A
T
R
E
R
V
V
P
P
Site 13
T119
P
P
P
K
K
R
R
T
G
V
S
F
G
D
E
Site 14
S122
K
K
R
R
T
G
V
S
F
G
D
E
H
F
A
Site 15
S132
D
E
H
F
A
E
T
S
Y
Y
F
E
G
G
L
Site 16
Y133
E
H
F
A
E
T
S
Y
Y
F
E
G
G
L
R
Site 17
Y134
H
F
A
E
T
S
Y
Y
F
E
G
G
L
R
K
Site 18
Y145
G
L
R
K
V
R
P
Y
Y
F
D
F
R
T
Y
Site 19
Y146
L
R
K
V
R
P
Y
Y
F
D
F
R
T
Y
C
Site 20
S161
K
G
R
W
V
G
H
S
L
L
H
V
F
S
T
Site 21
S167
H
S
L
L
H
V
F
S
T
E
F
R
A
Q
P
Site 22
Y178
R
A
Q
P
L
A
Y
Y
E
A
A
V
R
A
G
Site 23
T210
D
N
D
F
L
R
N
T
V
H
R
H
E
P
P
Site 24
T219
H
R
H
E
P
P
V
T
A
E
P
I
R
L
L
Site 25
S278
H
R
L
D
R
L
T
S
G
V
L
M
F
A
K
Site 26
Y306
D
R
Q
L
E
K
E
Y
V
C
R
V
E
G
E
Site 27
T346
P
R
G
K
P
C
E
T
V
F
Q
R
L
S
Y
Site 28
S352
E
T
V
F
Q
R
L
S
Y
N
G
Q
S
S
V
Site 29
Y353
T
V
F
Q
R
L
S
Y
N
G
Q
S
S
V
V
Site 30
S358
L
S
Y
N
G
Q
S
S
V
V
R
C
R
P
L
Site 31
T366
V
V
R
C
R
P
L
T
G
R
T
H
Q
I
R
Site 32
Y389
P
I
L
N
D
P
I
Y
N
S
V
A
W
G
P
Site 33
S391
L
N
D
P
I
Y
N
S
V
A
W
G
P
S
R
Site 34
S397
N
S
V
A
W
G
P
S
R
G
R
G
G
Y
I
Site 35
Y403
P
S
R
G
R
G
G
Y
I
P
K
T
N
E
E
Site 36
T407
R
G
G
Y
I
P
K
T
N
E
E
L
L
R
D
Site 37
S436
D
L
C
E
G
D
L
S
P
G
L
T
D
S
T
Site 38
T440
G
D
L
S
P
G
L
T
D
S
T
A
P
S
S
Site 39
S442
L
S
P
G
L
T
D
S
T
A
P
S
S
E
L
Site 40
T443
S
P
G
L
T
D
S
T
A
P
S
S
E
L
G
Site 41
S446
L
T
D
S
T
A
P
S
S
E
L
G
K
D
D
Site 42
S447
T
D
S
T
A
P
S
S
E
L
G
K
D
D
L
Site 43
T477
A
A
P
Q
E
L
D
T
I
A
L
A
S
E
K
Site 44
Y523
M
F
L
H
A
L
R
Y
K
G
P
G
F
E
Y
Site 45
Y530
Y
K
G
P
G
F
E
Y
F
S
P
M
P
A
W
Site 46
S532
G
P
G
F
E
Y
F
S
P
M
P
A
W
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation