KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CHPF
Full Name:
Chondroitin sulfate synthase 2
Alias:
Chondroitin glucuronyltransferase II; Chondroitin-polymerizing factor; EC 2.4.1.175; EC 2.4.1.226; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II
Type:
Transferase
Mass (Da):
85495
Number AA:
775
UniProt ID:
Q8IZ52
International Prot ID:
IPI00465319
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0032580
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0050510
GO:0047238
GO:0046872
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S48
G
P
P
Q
P
G
D
S
E
L
P
P
R
G
N
Site 2
T56
E
L
P
P
R
G
N
T
N
A
A
R
R
P
N
Site 3
S64
N
A
A
R
R
P
N
S
V
Q
P
G
A
E
R
Site 4
Y91
W
E
P
R
V
L
P
Y
H
P
A
Q
P
G
Q
Site 5
Y108
K
K
A
V
R
T
R
Y
I
S
T
E
L
G
I
Site 6
S110
A
V
R
T
R
Y
I
S
T
E
L
G
I
R
Q
Site 7
S126
L
L
V
A
V
L
T
S
Q
T
T
L
P
T
L
Site 8
T129
A
V
L
T
S
Q
T
T
L
P
T
L
G
V
A
Site 9
T140
L
G
V
A
V
N
R
T
L
G
H
R
L
E
R
Site 10
T152
L
E
R
V
V
F
L
T
G
A
R
G
R
R
A
Site 11
T204
L
V
P
D
T
T
Y
T
E
A
H
G
L
A
R
Site 12
Y225
L
A
S
A
A
H
L
Y
L
G
R
P
Q
D
F
Site 13
T238
D
F
I
G
G
E
P
T
P
G
R
Y
C
H
G
Site 14
Y242
G
E
P
T
P
G
R
Y
C
H
G
G
F
G
V
Site 15
S272
G
C
R
N
D
I
V
S
A
R
P
D
E
W
L
Site 16
Y300
G
D
H
E
G
V
H
Y
S
H
L
E
L
S
P
Site 17
S301
D
H
E
G
V
H
Y
S
H
L
E
L
S
P
G
Site 18
S306
H
Y
S
H
L
E
L
S
P
G
E
P
V
Q
E
Site 19
T348
A
R
A
E
L
E
R
T
Y
Q
E
I
Q
E
L
Site 20
Y349
R
A
E
L
E
R
T
Y
Q
E
I
Q
E
L
Q
Site 21
S383
P
V
G
I
P
A
P
S
R
P
A
S
R
F
E
Site 22
S387
P
A
P
S
R
P
A
S
R
F
E
V
L
R
W
Site 23
Y396
F
E
V
L
R
W
D
Y
F
T
E
Q
H
A
F
Site 24
S404
F
T
E
Q
H
A
F
S
C
A
D
G
S
P
R
Site 25
S409
A
F
S
C
A
D
G
S
P
R
C
P
L
R
G
Site 26
Y437
L
E
E
L
N
R
R
Y
H
P
A
L
R
L
Q
Site 27
Y452
K
Q
Q
L
V
N
G
Y
R
R
F
D
P
A
R
Site 28
T464
P
A
R
G
M
E
Y
T
L
D
L
Q
L
E
A
Site 29
T473
D
L
Q
L
E
A
L
T
P
Q
G
G
R
R
P
Site 30
T482
Q
G
G
R
R
P
L
T
R
R
V
Q
L
L
R
Site 31
S492
V
Q
L
L
R
P
L
S
R
V
E
I
L
P
V
Site 32
Y549
A
L
T
L
L
L
L
Y
E
P
R
Q
A
Q
R
Site 33
S602
L
R
L
M
D
L
L
S
K
K
H
P
L
D
T
Site 34
T609
S
K
K
H
P
L
D
T
L
F
L
L
A
G
P
Site 35
T621
A
G
P
D
T
V
L
T
P
D
F
L
N
R
C
Site 36
T666
P
P
E
L
G
R
D
T
G
R
F
D
R
Q
A
Site 37
S675
R
F
D
R
Q
A
A
S
E
A
C
F
Y
N
S
Site 38
Y684
A
C
F
Y
N
S
D
Y
V
A
A
R
G
R
L
Site 39
S695
R
G
R
L
A
A
A
S
E
Q
E
E
E
L
L
Site 40
S704
Q
E
E
E
L
L
E
S
L
D
V
Y
E
L
F
Site 41
T735
L
Q
R
Y
R
A
Q
T
C
S
A
R
L
S
E
Site 42
S737
R
Y
R
A
Q
T
C
S
A
R
L
S
E
D
L
Site 43
S741
Q
T
C
S
A
R
L
S
E
D
L
Y
H
R
C
Site 44
Y745
A
R
L
S
E
D
L
Y
H
R
C
L
Q
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation